A5086479688- Traditional Chinese Medicine Analysis
- Pharmacological Effects of Natural Compounds
- Metabolomics and Mass Spectrometry Studies
- Ginseng Biological Effects and Applications
- Connexins and lens biology
- Forensic Toxicology and Drug Analysis
- Flowering Plant Growth and Cultivation
- Cardiac Imaging and Diagnostics
- Phytochemistry and Biological Activities
- Mass Spectrometry Techniques and Applications
- Ion channel regulation and function
- Stress Responses and Cortisol
- Natural product bioactivities and synthesis
- Powdery Mildew Fungal Diseases
- Advanced MRI Techniques and Applications
- Magnolia and Illicium research
- Cardiac Ischemia and Reperfusion
- Tryptophan and brain disorders
- Polysaccharides and Plant Cell Walls
- Phytochemicals and Antioxidant Activities
- Food Drying and Modeling
- Nicotinic Acetylcholine Receptors Study
- Neurological Disease Mechanisms and Treatments
- Drug-Induced Hepatotoxicity and Protection
Guangzhou University of Chinese Medicine
2023-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2024
Zunyi Medical University
2022-2024
China Academy of Chinese Medical Sciences
2022
Jiangxi University of Traditional Chinese Medicine
2022
Hypericin is widely utilized for its precise antidepressant properties, but exact mechanism remains unclear. Gap junctions, which were predominantly expressed in astrocytes the central nervous system, are concerned with pathogenesis of depression. However, role hypericin gap junctional dysfunction depression has rarely been investigated. Here, we found that junctions ultra-structurally broadened chronic unpredictable stress (CUS) rat model depression, while repaired junctions. Suppression by...
In myocardial ischemia, optimizing the metabolic phenotype to improve cardiac function is critical. Naoxintong capsules (NXT) are widely prescribed in Chinese medicine for treatment of cerebrovascular and cardiovascular diseases. this study, a rat model infarction was established by ligation left anterior descending coronary artery. The structure heart were evaluated using echocardiography. pathological changes myocardium volume collagen fraction (CVF) examined hematoxylin-eosin (HE)...
Dispensing granule, an innovative preparations of traditional Chinese medicine (TCM) decoction. The convenience carrying and using makes this herbal product more attractive in clinical practice. However, the consistency quality efficacy such granules after constituting into a decoction compared with decoctions is subject controversy. In present study, BXHPT (Banxia Houpo Tang) was evaluated as typical TCM. Consistency dispensing performed by chemical analysis assessment biological activity....
Du-Zhi pill (DZP) is widely used as a Chinese medicine in treating cerebral ischemia. UHPLC-Q-TOF-MS/MS techniques were to detect and identify the metabolites rat brain samples of normal middle artery occlusion (MCAO) model rats administered with DZP. It was tentatively found that 43 prototypes 93 could be identified samples. Normal MCAO contained 19 prototype components. Eight components only detected samples, while 16 determined 47 had been rats, 86 placed rats. There 40 common both Seven...
Objective: The study aimed to analyze the core active compounds and potential mechanism of Shuganning injection (SGNI) through network pharmacology with biological experiments. Methods: Active targets SGNI were screened from Traditional Chinese Medicine Systems Pharmacology Database Analysis Platform (TCMSP) Targetnet database, whereas liver disease-related identified Genecards Online Mendelian Inheritance in Man databases. “compound-target” “protein-protein interaction” networks...
Du-Zhi pill (DZP) is a traditional Chinese medicine (TCM) formula with remarkable clinical efficacy in the treatment of stroke. By exploring components DZP, absorbed prototype constituents and metabolites plasma, urine feces are great significance clarifying effective substances this prescription. Herein, reliable method using ultra-performance liquid chromatography coupled quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS) was established order to conduct comprehensive analysis...
In the present study, thin-layer drying has been applied to improve efficiency and perfume production from E. rutaecarpa. Thus, effects of kinetics temperature on quality rutaecarpa for essential oil were studied. Seven kinds mathematical models, such as Midilli et al., Overhults al. Lewis model verify relationship between moisture ratio time in process. The could simulate process very well. oils obtained before after different extracted via steam distillation, components identified with...