- Uterine Myomas and Treatments
- Endometriosis Research and Treatment
- Minimally Invasive Surgical Techniques
- Intestinal and Peritoneal Adhesions
- Hernia repair and management
- Gynecological conditions and treatments
- Endometrial and Cervical Cancer Treatments
- Pelvic and Acetabular Injuries
- Surgical Sutures and Adhesives
- Surgical Simulation and Training
- Pelvic floor disorders treatments
- Respiratory Support and Mechanisms
- Ovarian cancer diagnosis and treatment
- Colorectal Cancer Surgical Treatments
- Anorectal Disease Treatments and Outcomes
- Abdominal Surgery and Complications
- Soft tissue tumor case studies
- Augmented Reality Applications
- Cardiovascular and Diving-Related Complications
- Chemotherapy-induced organ toxicity mitigation
- Carcinogens and Genotoxicity Assessment
- Cardiac Arrest and Resuscitation
- Appendicitis Diagnosis and Management
- BRCA gene mutations in cancer
- Ureteral procedures and complications
Berlin Center for Epidemiology and Health Research
2015-2022
Center for Special Minimally Invasive and Robotic Surgery
2014
Pius Hospital Oldenburg
2009-2013
Klinik für Frauenheilkunde
2010
Heidelberg University
2010
Justus-Liebig-Universität Gießen
2010
Background: Intra-abdominal adhesions arise after more than 50% of all abdominal operations and are an important source postoperative complications.They attach normally separated organs to each other can cause major problems for the affected patients by giving rise small bowel obstruction, chronic pelvic pain, dyspareunia, infertility, higher complication rates in subsequent operations.They also a frequent medicolegal conflict.Thus, every physician should be familiar with their mechanism...
This study aims to evaluate the number of cases occult uterine malignancies in all LASH surgeries at MIC clinic (Berlin) and verify how operative technique affects prognosis disease.Data 10,731 patients who underwent a standardized surgery with electric power morcellation between 1998 April 30, 2014 were retrospectively analyzed. Main indication for was symptomatic myomas (81.3 %).No intra-operative complication caused by use morcellator. In total, six sarcomas (0.06 %), including four...
Abstract Background The DNA damage by platinum cytostatics is thought to be the main cause of their cytotoxicity. Therefore measurement induced cis- and carboplatin should reflect sensitivity cancer cells toward chemotherapeutics. Methods in primary ovarian carcinomas was determined alkaline comet assay. In parallel, reduction cell viability measured fluorescein diacetate (FDA) hydrolysis Results While assay isolated showed a high degree after 24 h treatment, revealed no cytotoxicity that...
A clinical trial is a prospective study designed to establish the safety and efficacy of investigational devices in humans, accordance with strict guidelines Food Drug Administration (FDA; USA) or European Medicines Agency (EMA; Europe). Before first-in-human initiated, preclinical studies product are mandatory, results should be sufficient indicate that device acceptably safe for proposed evaluation human subjects. The present paper describes an experience trials, highlighting ways avoiding...
Laparoscopic sacropexy was found to be a safe and efficacious surgical treatment for genital prolapse with low rate of perioperative complications favorable anatomic results.
Background and Objectives:The aim of this study was to evaluate postoperative patient satisfaction in women after laparoscopic supracervical hysterectomy (LASH).Methods:A retrospective by a mailed questionnaire among 2334 who underwent via LASH at the MIC-Klinik, Berlin, between 1998 2004 conducted. Indications for were uterus myomatosus, adenomyosis uteri, disorders bleeding, genital descensus. The operation technique standardized remained consistent throughout observation period. Pearson's...
Endometriosis is a heterogeneous disease characterized by range of different presentations. It usually diagnosed when patients present with pain and/or infertility, but it has also been in asymptomatic patients. Because the diagnostic approaches and diverse therapies, time to diagnosis can vary considerably definitive may be delayed, some cases not being for several years. have many unmet needs. A systematic registration follow-up endometriosis could useful obtain an insight into course...
Although myomectomy is widely accepted in women of childbearing age who wish to retain their fertility, the extent which myomas affect fertility and whether removal improves this remain unclear. This study aimed elucidate favourable surgical approach with uterine infertility. retrospective, follow-up was carried out three centres Germany. Data on had undergone via laparoscopy, laparotomy or conversion 2000-04 were collected analysed. Fertility outcome after assessed by postal questionnaire a...
We conducted a prospective randomized single blind – subject study in the University Clinic of Gynecology Pius-Hospital Oldenburg. The primary objective ADBEE was to assess safety and manageability ADBLOCK when used as an adjunct laparoscopic surgery for myomas women wishing improve pregnancy outcomes. population included 32 aged between 18–45 years, good general health condition, who have not completed their family planning are undergoing ('virgin') myomectomy with aim patients were 2...
Background: Over the past decades, our knowledge and understanding of adhesions adhesion-related complications has increasingly grown it become evident that have significant implications for patients, physicians healthcare system. The question arises whether this resulted in greater awareness problems among practicing appropriate patient education on topic daily practice. following article provides a brief overview important subject adhesions, discusses current patients doctors addresses...
In female patients presenting a tumor of the lower abdominal wall especially after cesarian section, an endometriotic as well aggressive desmoid should be considered. Symptoms in correlation with monthly period can facilitate presurgical differentiation between endometriosis and fibromatosis. Ultrasound reveals typical location both tumors its remarkable sonographic appearance. clinical practice, fibromatosis is very rare disease. We present case 25-year-old pregnant discuss diagnostic...
To perform hysterectomy in uterus myomatosus, there are several surgical techniques. For a uterine weight of >1000 g, after caesarean section and nullipara per vaginam, the most common technique for patients is laparotomiam. A new endoscopical developed to treat such avoid laparotomy described this case report: laparoscopic combined (LACH) using change-over technique. Adhesiolysis, preparation ureters bladder morcellation 2480 g were performed minimally-invasive two steps, from one side...
Background and Objective . The aim of this study was to assess the subjective outcome following laparoscopic sacropexy. Methods We performed a retrospective cohort among women treated for descensus with sacropexy between January 2000 December 2007. 310 patients received questionnaires during followup assessing major pre- postoperative symptoms overall satisfaction. Results 214 (69%) responded questionnaire. Mean 24.5 months. number back or lower abdominal pain, foreign body sensation in...
<b><i>Background and Aims:</i></b> This controlled trial with II-1 evidence compared the safety efficacy of new laparoscopic-assisted combined hysterectomy (LACH) standard surgical technique vaginal (LAVH) in general patients displaying risk factors (large uterus, nulliparity, prior caesarean section). <b><i>Methods:</i></b> From June 2007 to September 2008, 101 underwent a at Clinic Gynaecology, Obstetrics Gynaecological Oncology Pius...
Hysterectomy now belongs to standard gynecological procedures. Moreover, a shift towards laparoscopic techniques is ever more apparent as they provide many advantages such less traumatization and shorter convalescence. Large uteri are still mentioned contraindications for hysterectomy even though those patients might benefit from the lower morbidity associated with minimal invasive techniques. In this study, largest reported so far, we analyzed intraoperative postoperative complications well...
Objective:Safe and reliable access systems are crucial in laparoscopy, trocar dislodgement is still a common frustrating problem. Wall emphysema can occur besides the risky prolongation of surgical procedure. Wall-anchoring components provide better hold device. This comparative analysis assesses frequency time-sparing effect on intervention 3 different systems, including an innovation field access-providing systems.Methods:Patients who underwent laparoscopy for various gynecological...
Today, even though minimally invasive approaches have become standard worldwide, large uteri are still mainly removed by means of open abdominal approaches. The present case describes the successful removal largest uterus ever reported (4065 g) laparoscopy-assisted supracervical hysterectomy (LASH). We combined LASH with changeover technique which allows a better access and view. further explain how this approach for safe any size.