A5030701249- Receptor Mechanisms and Signaling
- Cardiac Fibrosis and Remodeling
- Cardiac Ischemia and Reperfusion
- Cardiac electrophysiology and arrhythmias
- Phosphodiesterase function and regulation
- Adipose Tissue and Metabolism
- Conducting polymers and applications
- Phytochemistry and Biological Activities
- Science and Education Research
- Electrochemical sensors and biosensors
- Botanical Research and Applications
- Cardiomyopathy and Myosin Studies
- Cardiac Arrest and Resuscitation
- Renal function and acid-base balance
- Heart Failure Treatment and Management
- Muscle metabolism and nutrition
- Education Pedagogy and Practices
- Electrospun Nanofibers in Biomedical Applications
- Medicinal Plants and Neuroprotection
- Saffron Plant Research Studies
- Ion channel regulation and function
- Estrogen and related hormone effects
- Pharmacological Effects and Assays
- Bone Tissue Engineering Materials
- Renin-Angiotensin System Studies
Universidade Federal de Sergipe
2021-2024
Universidade Federal de São Paulo
2023
Cedars-Sinai Smidt Heart Institute
2023
Cedars-Sinai Medical Center
2023
The search for new biomaterials has increased continuously in recent years and, this context, the application of polypyrrole (PPy) as a promising material function been reported result positive responses, such bioactivity and biocompatibility. In study, PPy was obtained through modifications/adaptations made methodologies previous papers, which focused mainly on conductive properties. use additives synthesis significantly improves biomedical area, depends directly diversity structural...
S-Limonene (s-Lim) is a monocyclic monoterpene found in variety of plants and has been shown to present antioxidant cardioprotective activity experimental models myocardial infarction. The aim this study was evaluate the potential mechanism by which s-Lim exerts its antiarrhythmic effect, focusing on blockade β-adrenoceptor (β-AR) effects various vivo vitro parameters, including electrocardiogram (ECG) measurements, left ventricular developed pressure (LVDP), β-adrenergic pathway, sarcomeric...
Naringin is a flavonoid glycoside found in citrus fruits and grapes with wide range of therapeutic actions. We aimed to study the inotropic effect naringin on rat-isolated atria, dissecting intracellular mechanisms involved this response. Concentration-response curves (0.003-6 mM) were obtained before after pre-incubation selective antagonists. Our results showed that presented biphasic response, positive at low middle concentrations (0.003-2.0 mM), negative high (above 3 mM). Pre-incubation...
A indústria tem forte interesse sobre a Genipa americana L. para produção de corante partir do extrato ou suco fruto. Atualmente, tem-se utilizado o formulação agentes e loções corporais antioxidantes, tintura alimentícia tatuagem produtos antileucemicos. Estas novas tecnologias estão embasadas em sua composição quimica com presença flavonóides e, principalmente, iridóide genipin. O estudo teve por finalidade apresentar estado da arte atividade biológica uso jenipapeiro. Observou-se trabalho...
Plants are important sources of secondary metabolites responsible for various biological activities. In this research, was evaluated the effect action ethyl acetate fraction Syzygium cumini leaves (Sc-AcOEt) in antimicrobial activity, contractile and electrical effects isolated rat hearts chemical characterization. Antimicrobial activity assessed using disk-diffusion method determination minimum inhibitory concentration. The were tested Langendorf method. characterization through...
A celulose é um biopolímero com elevado potencial de aplicação em áreas como a têxtil, alimentos e farmacêutica. Porém, baixa solubilidade água dificulta tais aplicações, o que pode ser contornado via modificações na estrutura, incluindo oxidação medida por N-oxil-2,2,6,6-tetrametilpiperidina (TEMPO). Além aprimorar solubilidade, as abrem oportunidades obtenção novos materiais, dentre os quais hidrogéis, podem aplicados adsorventes, curativos ou carreadores fármacos. O presente trabalho...