- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Mindfulness and Compassion Interventions
- Healthcare professionals’ stress and burnout
- Schizophrenia research and treatment
- COVID-19 and Mental Health
- Neural dynamics and brain function
- Digital Mental Health Interventions
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neural and Behavioral Psychology Studies
- Mental Health Treatment and Access
- Neurotransmitter Receptor Influence on Behavior
- Patient-Provider Communication in Healthcare
- Cancer survivorship and care
- Medical Malpractice and Liability Issues
- Psychosomatic Disorders and Their Treatments
- Medical Education and Admissions
- Mental Health via Writing
- Sleep and Wakefulness Research
- Stress Responses and Cortisol
- Family Support in Illness
- Tryptophan and brain disorders
- Neuroscience and Neuropharmacology Research
- Empathy and Medical Education
- Workplace Violence and Bullying
Harvard University
2023-2025
Massachusetts General Hospital
2023-2025
Athinoula A. Martinos Center for Biomedical Imaging
2023-2025
Texas Tech University
2019-2025
University Memory and Aging Center
2021-2022
University of California, San Francisco
2015-2022
Maastricht University
2021
National University Hospital
2020-2021
National University of Singapore
2021
Beijing Anding Hospital
1988
Burnout, depression, and anxiety are highly prevalent among medical students, which often leads to their attrition. We aim assess the inter-relationships of burnout, symptoms with dropout intention Chinese undergraduates using network analysis.A total 3,648 were recruited through snowball sampling. Learning burnout scale, 9-item Patient Health Questionnaire (PHQ-9), General Anxiety Disorder Scale (GAD-7) was used symptoms, respectively. EBICglasso model estimate network. compared based on...
Abstract Jhanas are profound states of mind achieved through advanced meditation, offering valuable insights into the nature consciousness and tools to enhance well-being. Yet, its neurophenomenology remains limited due methodological difficulties rarity meditation practitioners. We conducted a highly exploratory study investigate jhanas in an intensively sampled adept meditator case (4 hr 7T fMRI collected 27 sessions) who performed jhana rated specific aspects experience immediately...
Meditation has been integral to human culture for millennia, deeply rooted in various spiritual and contemplative traditions. While the field of science made significant steps toward understanding effects meditation on health well-being, there little study advanced meditative states, including those achieved through intense concentration absorption. We refer these types states as concentrative absorption (ACAM), characterized by with object leading heightened attention, clarity, energy,...
Abstract Advanced meditation such as jhana can produce various altered states of consciousness (jhanas) and cultivate rewarding psychological qualities including joy, peace, compassion, attentional stability. Mapping the neurobiological substrates inform development application advanced to enhance well‐being. Only two prior studies have attempted investigate neural correlates meditation, rarity adept practitioners has largely restricted size extent these studies. Therefore, examining...
The doctor–patient relationship (DPR) is essential in the process of medical consultations and treatments. Poor DPR may lead to poor outcomes, violence against doctors, a negative perception healthcare system. Little known about how affected during this novel coronavirus disease 2019 (COVID-19) pandemic. This cross-sectional study aimed explore COVID-19 There were 1,903 participants China (95% response rate) who recruited pandemic online via convenience snowball sampling. Several...
A high attrition rate in medical students has exacerbated the physician shortage China. However, few studies have explored risk factors of dropout intention postgraduates. This study compared prevalence and mental distress between non-medical postgraduates China investigated for intention. also impact postgraduates' perception Chinese healthcare environment on their status intention.This cross-sectional was conducted using online questionnaires from October 2020 to April 2021. Convenience...
Abstract Objective To assess the quality of doctor-patient relationship (DPR) in China and possible influencing factors during COVID-19 period from patient’s perspective. Methods An online survey was carried out nationwide March 12, 2020 to 30, via a convenience sampling strategy. Patients who met inclusion criteria were invited complete questionnaire regarding DPR, including sociodemographic information, Patient-Doctor Relationship Questionnaire (PDRQ-9), for DPR pandemic. Results A total...
Anxiety frequently occurs with major depressive disorder (MDD) but to a different extent in the various subtypes. Psychotic depression (PMD) is severe subtype of MDD that under-identified and under-studied. We investigated prevalence related risk factors anxiety PMD patients. A total 1718 first episode drug naïve patients were recruited. Measures included Hamilton Depression Scale (HAMD), Clinical Global Impression-Severity scale (CGI-S), (HAMA), positive symptom Positive Negative Syndrome...
Advanced meditation has been associated with long- and short-term psychological changes such as bliss, profound insight, transformation of well-being. However, most advanced neuroimaging analyses have implemented primarily spatially-localized approaches, focusing on discrete regional in activity rather than distributed dynamics. The present study uses a geometric eigenmode decomposition ultrahigh field-strength 7T functional magnetic resonance imaging (fMRI) data from an intensely sampled...
Background Despite the high prevalence of mental stress among physicians, reliable screening tools are scarce. This study aimed to evaluate capability Physician Well-Being Index (PWBI) in identifying distress and adverse consequences Chinese physicians.
Abstract There is growing scientific interest in advanced meditation, and particularly the Theravada Buddhist concentrative absorption meditation known as jhana (ACAM-J). ACAM-J includes a series of eight consecutive meditative states, which are radically altered states consciousness. The neuroscience ACAM-J, specifically brain reorganization, remains underspecified part due to difficulty finding studying expert meditators challenges related laboratory investigation ACAM-J. Using nonlinear...
Background: There are few studies about stigma associated with mental disorders among non-mental health professionals in general hospitals China. This study seeks to explore the health-related and desire for social distance of Hunan Province Methods: The was carried out 1123 six by using a questionnaire case vignette describing either schizophrenia, depression or generalized anxiety disorder (GAD). Questions attitudes participants other people towards individuals disorders, willingness...
Structural and task-based functional studies associate emotion reading with frontotemporal brain networks, though it remains unclear whether connectivity (FC) alone predicts ability. The predominantly salience semantic appraisal (SAN) networks are selectively impacted in neurodegenerative disease syndromes like behavioral-variant dementia (bvFTD) semantic-variant primary progressive aphasia (svPPA). Accurate identification diminishes some of these patients, but investigating the source this...
Study objective To investigate the association between family cancer caregivers’ unmet daily needs and emotional states of depression, anxiety stress across their care recipient’s treatment phases. Method A cross-sectional study design self-report questionnaires were used. Family caregivers (N = 237) patients in ambulatory clinics recruited from May to December 2017, completed a sociodemographic medical questionnaire, Depression Anxiety Stress Scale Needs Assessment Caregivers-Cancer Scale....
Abnormal thyroid function in major depressive disorder (MDD) has been studied extensively, but the results still remain inconsistent. In China, few large-scale studies have investigated differences levels of hormones between patients with MDD and healthy controls (HCs). this retrospective, cross-sectional study, 535 998 HCs were included. We compared (FT3, FT4, TSH) two groups, as well distribution within outside normal ranges. The showed that all three significantly lower than HCs, which...
Abstract The outbreak of the novel coronavirus disease 2019 (COVID-19) has posed a great impact on people’s mental health, especially for undergraduate students. This study aimed to compare health conditions and academic burnout between medical non-medical undergraduates in China when COVID-19 pandemic is mitigating. A cross-sectional online survey was conducted among 4,972 October 2020 April 2021, basically under control. included basic demographics information standardized scales evaluate...
Background: Doctor-patient relationship (DPR) is very important for patient outcomes, especially during a public health emergency like the COVID-19 pandemic. However, few studies have evaluated DPR and related sentiments from medical professionals' perspectives. Thus, aim of study to provide better understanding perspectives pandemic in China. Methods: A total 979 professionals, including doctors, nurses, technicians, other workers completed series questionnaires evaluate their attitudes...
Loss of warmth is well-documented in behavioral variant frontotemporal dementia (bvFTD) and semantic primary progressive aphasia (svPPA) at a group level, has been linked to salience (SN) semantic-appraisal (SAN) network atrophy. However, clinical observations individual patients show much greater heterogeneity, thus measuring this variability identifying the underlying neurologic mechanisms critical step for understanding symptom profile any one patient. We used reliable change indexes with...
Abstract The intrinsic connectivity of the salience network (SN) plays an important role in social behavior, however directional influence that individual nodes have on each other has not yet been fully determined. In this study, we used spectral dynamic causal modeling to characterize effective patterns SN for 44 healthy older adults and patients with behavioral variant frontotemporal dementia (bvFTD) who focal dysfunction. We examined relationship connections individuals' socioemotional...
Background Workplace violence in healthcare settings is a significant public concern that profoundly impacts workers. However, there dearth of knowledge regarding the prevalence workplace and its correlation with suicidal ideation among undergraduate medical students China during their clinical training. The objective this study was to evaluate inflicted by patients or family members/visitors assess association students.
Abstract WHOQOL-AGE is a promising quality of life (QOL) tool that has not been fully validated in Asia. The present study aimed to verify its factor structure and psychometric properties among community-dwelling older adults Singapore. This was cross-sectional used data ( N = 593) from the Community Health Intergenerational interviewed between 2018 2021. Confirmatory analysis (CFA) examine WHOQOL-AGE, Cronbach’s alpha coefficients were employed internal consistency. Spearman’s rho...
Network neuroscience is an interdisciplinary field, which can be used to understand the brain by examining connections between its constituent elements. In recent years, application of network approaches study intricate nature structural and functional relationships within human has yielded unique insights into organization. this review, we begin defining providing overview common metrics that describe topology networks. We then present a detailed limited but growing body literature...