Neurofeedback training (NFT) of the alpha rhythm has been used for several decades but is still controversial in regards to its trainability and effects on working memory.Alpha frontoparietal region are associated with either intelligence or memory healthy subjects also related pathological states.In this study, NFT performances were explored.Fifty participants recruited randomly assigned into a group receiving 8-12-Hz amplitude (Alpha) random 4-Hz from range 7 20 Hz (Ctrl).Three sessions...

Health care researchers have recently developed several home-based sleep monitoring systems and mobile applications that support healthy by a user's environment, activities, or quality. This study describes the design evaluation of an electrooculogram (EOG)-based system for automatic monitoring. Compared with polysomnogram electroencephalogram recordings, EOG has advantage easy placement can be operated users themselves. We also intelligent eye mask is user friendly measuring stage Two...

A distinct high-voltage rhythmic spike (HVRS) discharge characterized by a barrage of negative spikes oscillating at 5-12 Hz was observed in chronically implanted Long Evans rats. Spontaneous HVRS discharges were exhibited 90% 40 rats and occurred during sudden arrest ongoing behavior (immobility) with occasional facial/whisker twitching. However, the function remains inconclusive to date has been associated alpha tremor/mu rhythm, attentive mu wave, absence seizure. To elucidate rats,...

Background and Purpose— Thermal stimulation (TS) is commonly used in orthopedic rehabilitation, but the role of TS facilitation sensorimotor recovery hemiplegic patients remains unknown. This study addressed issue intervention functional outcomes. Methods— Forty-six stroke survivors were randomly assigned to standard rehabilitation treatment plus (30 minutes daily for 6 weeks). Twenty-nine completed experiment. Six measures, including Brunnstrom stage, modified motor assessment scale,...

In this study, a wearable actigraphy recording device with low sampling rate (1 Hz) for power saving and data reduction high accuracy wake-sleep scoring method the assessment of sleep were developed.The developed recorder was successfully applied to overnight recordings 81 subjects simultaneous polysomnography (PSG) measurements. The total length reached 639.8 h. A based on concept movement density evaluation adaptive windowing proposed. Data from good (N = 43) poor 16) efficiency (SE) in...

Abstract Peroxisome proliferator‐activated receptors γ coactivator‐1α (PGC‐1α) may regulate the mitochondrial antioxidant defense system under many neuropathological settings. However, exact role of PGC‐1α in ischemic brain damage is still debate. Based on an experimental model transient global ischemia (TGI), this study evaluated hypothesis that activation signaling pathway protects hippocampal CA1 neurons against delayed neuronal death after TGI. In Sprague‐Dawley rats, significantly...

A considerable portion of epilepsy cannot be well treated by available therapies nowadays. Brain stimulation with closed-loop seizure control has recently been proposed as an innovative and effective alternative. portable wireless online controller in freely moving rats was developed shown several aspects advantages, including the following: 1) high accuracy real-time detection (92-99% during wake-sleep states); 2) low cost; 3) power consumption. The latency not greater than 0.6 s after...

To explore the role of autonomic nervous system in initiation sleep-wake transitions. Changes cardiovascular variability during transitions adult male Wistar-Kyoto rats on their normal daytime sleep were analyzed. A 6-h sleep-wakefulness recording session was performed. Electroencephalogram and electromyogram (EMG) signals subjected to continuous power spectral analysis, from which mean frequency electroencephalogram (MPF) EMG quantified. Active waking (AW), quiet (QS), paradoxical (PS)...

Abstract Delayed neuronal cell death occurs in the vulnerable CA1 subfield of hippocampus after transient global ischemia (TGI). We demonstrated previously, based on an experimental model TGI, that significantly increased content oxidized proteins hippocampal neuron was observed as early 30 min followed by augmentation PGC‐1α expression at 1 hr, well up‐regulation mitochondrial uncoupling protein 2 (UCP2) and superoxide dismutases (SOD2). Using same animal model, present study investigated...

The role of the autonomic nervous system in spontaneous hypertension during each stage sleep-wake cycle remains unclear. present study attempted to evaluate differences cardiac modulations among spontaneously hypertensive rats (SHR), normotensive Wistar-Kyoto (WKY), and Sprague-Dawley (SD) across cycles. Continuous power spectral analysis electroencephalogram, electromyogram, heart rate variability was performed unanesthetized free moving daytime sleep. Frequency-domain stationary R-R...

To explore whether spontaneous hypertension is associated with a change in sleep pattern rats.Adult male spontaneously hypertensive rats (SHR) were compared to normotensive Wistar-Kyoto (WKY) on their normal daytime pattern.Ten WKY and 10 SHR.All had electrodes implanted for polygraphic recordings. Weeks later, 5-hour sleep-weakfulness recording session was analyzed.Electroencephalogram electromyogram signals subjected continuous power spectral analysis, from which mean frequency of the...

The worldwide prevalence of epilepsy is approximately 1%, and 25% patients cannot be treated sufficiently by available therapies. Brain stimulation with closed-loop seizure control has recently been proposed as an innovative effective alternative. In this paper, a portable brain computer interface for was developed shown several aspects advantages, including high detection rate (92-99% during wake-sleep states), low false (1.2-2.5%), small size. electrical latency not greater than 0.6 s...

In recent years, an increasing number of people suffer from sleep disorders. Polysomnography (PSG) is commonly used in hospitals or centers to diagnose disorders because it continuously and simultaneously records multiple physiological signals during sleep. However, the excessive wired connections for conventional PSG often a problem that leads disturbance. Due high cost bulky body, traditional systems are not suitable recording at home. This paper proposes design implementation modularized...

Summary Purpose: Lamotrigine (LTG) is an effective clinical treatment for epilepsy associated with absence seizures. However, the impact of LTG administration in studies employing various animal models remains controversial. This study aimed to clarify outcomes on seizures and comorbid anxiety depression disorders Long‐Evans rats spontaneous spike‐wave discharges (SWDs). Methods: (10 mg/kg) or water vehicle was chronically administered perorally (twice daily 35 days). Cortical activities...

Objective: In this paper, the genetic fuzzy inference system based on expert knowledge for automatic sleep staging was developed. Methods: Eight features, including temporal and spectrum analyses of EEG EMG signals, were utilized as input variables. The rules sets constructed distributions feature values at different stages. Three experiments designed to develop evaluate proposed system. PSGs 32 healthy subjects 16 with insomnia included in experiment method. Finally, a complete scoring...

Paroxysmal 5- to 12-Hz high-voltage rhythmic spike (HVRS) activities, which are accompanied by whisker twitching (WT), found in Long Evans rats, but the function of these HVRS activities is still debated. In four major functional hypotheses discharges, i.e., alpha tremor, attention/mu rhythm, idling/mu and absence seizure, first two emphasize WT behavior bouts. Whisker movement primarily determined activation intrinsic extrinsic muscles. To clarify role simultaneous recording from cortex...

Study Objective:To clarify the cortical evoked responses in primary somatosensory cortex of rat under states waking, slow-wave sleep (SWS), paradoxical (PS), and spike-wave discharges (SWDs), which are associated with absence seizure.