- Heart Rate Variability and Autonomic Control
- Non-Invasive Vital Sign Monitoring
- EEG and Brain-Computer Interfaces
- Sleep and Wakefulness Research
- Neuroscience of respiration and sleep
- Obstructive Sleep Apnea Research
- Cardiac electrophysiology and arrhythmias
- Heart rate and cardiovascular health
- Blood Pressure and Hypertension Studies
- Cardiac Health and Mental Health
- Memory and Neural Mechanisms
- Sleep and related disorders
- Stress Responses and Cortisol
- Sleep and Work-Related Fatigue
- Neuroscience and Neuropharmacology Research
- Circadian rhythm and melatonin
- Mental Health Research Topics
- Ophthalmology and Visual Health Research
- Virtual Reality Applications and Impacts
- Cardiovascular and exercise physiology
- Phonocardiography and Auscultation Techniques
- Advanced Chemical Sensor Technologies
- Eating Disorders and Behaviors
- Cardiovascular Syncope and Autonomic Disorders
- Impact of Technology on Adolescents
National Yang Ming Chiao Tung University
2016-2025
Taipei City Hospital
2012-2025
Ministry of Health and Welfare
2015-2025
Bali Psychiatric Center
2023-2024
Taipei Veterans General Hospital
1996-2023
Mackay Medical College
2023
National Yang Ming University Hospital
2012-2021
National Taipei University
2008-2020
Taipei Medical University
2018
National Central University
2016
To clarify the influence of gender on sympathetic and parasympathetic control heart rate in middle-aged subjects subsequent aging process, variability (HRV) was studied normal populations women ( n = 598) men 472) ranging age from 40 to 79 yr. These groups were divided into eight strata at 5-yr intervals clinically diagnosed as having no hypertension, hypotension, diabetic neuropathy, or cardiac arrhythmia. Frequency-domain analysis short-term, stationary R-R performed, which reveals...
Recent animal studies have supported that Lactobacillus plantarum PS128 (PS128) can reduce the severity of anxiety and depression. However, previous did not focus on sleep quality mood humans. This study determines whether reduces depressive symptoms, regulates autonomic nervous system function, improves quality. Forty participants between 20 40 years age with self-reported insomnia were randomly assigned to two groups, a group placebo group, in double-blind trial. Participants took capsules...
Objectives To evaluate the applicability of changes in spectra systemic arterial pressure and heart rate signals prediction patient outcome an adult intensive care unit (ICU). compare prognostic predictability this method with Acute Physiology Chronic Health Evaluation II (APACHE II) scoring system. Design Prospective data collection from 52 ICU patients. Setting Adult at a large, university-affiliated, medical center. Patients Consecutive patients who were admitted to due noncardiac...
We applied simultaneous spectral analysis of electroencephalographic (EEG) and systemic arterial pressure signals in Sprague-Dawley rats to monitor the status consciousness cardiovascular functions during intravenous anesthesia with propofol assess their correlations plasma concentration. Our results support hypothesis that a 'threshold' concentration (1.7-1.8 micrograms/ml) exists for anesthesia. This threshold level, we further showed, may be attained by both i.v. bolus injection...
The aim of the study was to analyse, while controlling for identified covariates, effects morningness-eveningness on sleep quality shift nurses.Shift nurses had greater difficulty falling asleep or staying asleep, thus resulting in higher rates retiring from hospital. Existing research has addressed manpower demand and personal preferences assignment; however, concept endogenous rhythms is rarely considered.This analysis included 137 between ages 21-58. Nurses completed Horne Ostberg...
Bipolar II (BPII) depression is commonly misdiagnosed as unipolar (UD); however, an objective and reliable tool to differentiate between these disorders lacking. Whether cardiac autonomic function can be used a biomarker distinguish BPII from UD unknown.We recruited 116 591 physically healthy patients with UD, respectively, 421 volunteers aged 20-65 years. Interviewer self-reported measures of depression/anxiety severity were obtained. Cardiac was evaluated by heart rate variability (HRV)...
Global smartphone penetration has led to unprecedented addictive behaviors. To develop a use/non-use pattern by mobile application (App) in order identify problematic use, total of 79 college students were monitored the App for 1 month. The App-generated parameters included daily frequency, duration and median per epoch. We introduced two other parameters, root mean square successive differences (RMSSD) Similarity Index, explore similarity use non-use between participants. non-use-median...
Before caring for patients, video instruction is commonly used undergraduate medical students, and 360° virtual reality (VR) videos have gained increasing interest in clinical education. Therefore, the effect of immersive VR learning compared with two-dimensional (2D) skills acquisition should be evaluated. This randomized, intervention-controlled trial was aimed to assess whether improves students' effectiveness reduces cognitive load history taking physical examination (H&P) training. From...
Objective Executive function correlates with the parasympathetic nervous system (PNS) based on static heart rate variability (HRV) measurements. Our study advances this understanding by employing dynamic assessments of PNS to explore and quantify its relationship inhibitory control (IC).Methods We recruited 31 men aged 20–35 years. monitored their electrocardiogram (ECG) signals during administration Conners’ Continuous Performance Test-II (CCPT-II) a weekly basis over 2 weeks. HRV analysis...
Background: Peri‐operative hymodynamic instability is one of the major concerns for anesthesiologists when performing general anesthesia individuals with autonomic dysfunction. The purpose this study was to examine potential usage pre‐operative measurement heart rate variability (HRV) in identifying which individuals, or without diabetes, may be at risk blood pressure (BP) during anesthesia. Methods: We studied 46 patients diabetes and 87 ASA class II III undergoing elective surgery....
The aim of this study is to examine the relationship between changes in self-reported sleep symptoms and cardiac sympathovagal activity among women with postmenopausal insomnia (PI) who received auricular acupressure (AA) therapy.A pretest/posttest design was conducted at Taipei Veterans General Hospital, Taiwan, from August 2008 July 2009. Forty-five (mean ± SD age, 56.2 5.4 years) PI (4.9 3.5 years insomnia) an AA therapy course on five points every night before going for 4 weeks. Heart...
Objective Decreased heart rate variability (HRV) has been reported in generalized anxiety disorder (GAD), but the results are mixed. Little is known about impact of comorbid major depression (MD) on HRV GAD patients. Both issues necessitate further investigation. Methods Twenty unmedicated, physically healthy patients, 20 patients with a secondary diagnosis MD, 40 MD and 60 matched controls were recruited. We used Hamilton Anxiety Rating Scale Depression to assess severity, respectively....
Decreased heart rate variability (HRV) has been proposed in bipolar disorder. To date, there no adequate study that investigated resting HRV unmedicated patients with disorder the manic state.To examine whether mania is associated decreased HRV, 61 and 183 healthy volunteers aged 20-65 years were recruited for this case-control analysis. The Young Mania Rating Scale (YMRS), Clinical Global Impression-Severity, Hamilton Depression (HAM-D), Anxiety (HAM-A) used clinical ratings. Cardiac...
The role of the autonomic nervous system in spontaneous hypertension during each stage sleep-wake cycle remains unclear. present study attempted to evaluate differences cardiac modulations among spontaneously hypertensive rats (SHR), normotensive Wistar-Kyoto (WKY), and Sprague-Dawley (SD) across cycles. Continuous power spectral analysis electroencephalogram, electromyogram, heart rate variability was performed unanesthetized free moving daytime sleep. Frequency-domain stationary R-R...
Electroencephalogram (EEG) signals give important information about the vigilance states of a subject. Therefore, this study constructs real-time EEG-based system for detecting drowsy driver. The proposed uses novel six channels active dry electrode to acquire EEG non-invasively. In addition, it TMS320VC5510 DSP chip as algorithm processor, and MSP430F149 controller achieve portable system. This implements stationary wavelet transform extract two features signal: integral zero crossings...