Shen‐Kou Tsai

ORCID: 0000-0003-1560-4387
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About
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Research Areas
  • Anesthesia and Pain Management
  • Anesthesia and Sedative Agents
  • Congenital Heart Disease Studies
  • Cardiac Valve Diseases and Treatments
  • Nausea and vomiting management
  • Cardiovascular and Diving-Related Complications
  • Airway Management and Intubation Techniques
  • Cardiac, Anesthesia and Surgical Outcomes
  • Anesthesia and Neurotoxicity Research
  • Tracheal and airway disorders
  • Aortic Disease and Treatment Approaches
  • Infective Endocarditis Diagnosis and Management
  • Cardiac Structural Anomalies and Repair
  • Cardiac Ischemia and Reperfusion
  • Cardiac and Coronary Surgery Techniques
  • Pain Management and Opioid Use
  • Atrial Fibrillation Management and Outcomes
  • Coronary Artery Anomalies
  • Pericarditis and Cardiac Tamponade
  • Retinal Diseases and Treatments
  • Pain Mechanisms and Treatments
  • Vascular anomalies and interventions
  • Pediatric Pain Management Techniques
  • Cardiac Arrhythmias and Treatments
  • Flavonoids in Medical Research

Cheng Hsin General Hospital
1970-2023

National Taiwan University
1998-2023

Chinese Medical Association
2021

Sichuan University
2017

University of Alabama at Birmingham
2008

National Yang Ming Chiao Tung University
1998-2006

Taipei Veterans General Hospital
1985-2006

National Taiwan University Hospital
1999-2006

Buddhist Tzu Chi General Hospital
2006

Mackay Memorial Hospital
2004-2006

Pruritus is a common side effect of intrathecal morphine injection for postoperative pain control. Its incidence especially high in patients undergoing cesarean delivery. We investigated the effectiveness ondansetron preventing morphine-induced pruritus such patients. included 60 consecutive nonbreastfeeding women who were scheduled elective After administration spinal anesthesia with bupivacaine and 0.15 mg injection, randomly divided into three groups. Group 1 received placebo (normal...

10.1097/00000539-200007000-00032 article EN Anesthesia & Analgesia 2000-07-01

Retinal ischemia-associated ocular disorders are vision threatening. This study examined whether the flavonoid baicalein is able to protect against retinal ischemia/reperfusion.Using rats, intraocular pressure was raised 120 mmHg for 60 min induce ischemia. In vitro, an ischemic-like insult, namely oxidative stress, established by incubating dissociated cells with 100 μM ascorbate and 5 FeSO4 (iron) 1 h. The rats or had been pretreated (in vivo: 0.05 0.5 nmol; in vitro: μM), vehicle (1%...

10.1089/jop.2012.0179 article EN Journal of Ocular Pharmacology and Therapeutics 2013-03-28

Pruritus is a common side effect of intrathecal morphine injection for postoperative pain control. Its incidence especially high in patients undergoing cesarean delivery. We investigated the effectiveness ondansetron preventing morphine-induced pruritus such patients. included 60 consecutive nonbreastfeeding women who were scheduled elective After administration spinal anesthesia with bupivacaine and 0.15 mg injection, randomly divided into three groups. Group 1 received placebo (normal...

10.1213/00000539-200007000-00032 article EN Anesthesia & Analgesia 2000-07-01

Abstract We have reported recently that intrathecal (i.t.) injection of interleukin‐1β (IL‐1β), at a dose 100 ng, induces inducible nitric oxide synthase (iNOS) expression and (NO) production in the spinal cord results thermal hyperalgesia rats. This study further examines role mitogen‐activated protein kinase (MAPK) i.t. IL‐1β‐mediated iNOS–NO cascade nociceptive signal transduction. All rats were implanted with an catheter either or without additional microdialysis probe. Paw withdrawal...

10.1111/j.1471-4159.2005.03226.x article EN Journal of Neurochemistry 2005-06-22

Botulinum toxin type A (BTX-A®) has been widely used in many clinical disorders including migraine, cervical dystonia, etc. The use of BTX-A neuropathic pain, however, is uncommon, and the application anti-nociceptive effect botulinum emerging. Here we report a case an 80-year-old man who suffered from severe pain post-herpetic neuralgia which was refractory to usual therapies. However, this dramatically relieved by multiple injection relief lasted 52 days.

10.1111/j.1526-4637.2006.00100.x article EN Pain Medicine 2006-01-01

In Brief Dexamethasone is an effective antiemetic drug, but its mechanism of action unclear. We designed this study to investigate the direct dexamethasone in medulla cats. By using oscillographic vomiting model, decerebrated cats received microinjections 100 nL (1 μg, n = 7; 0.1 7) into bilateral nuclei tractus solitarii, which led a significant prolongation latency 6.4 ± 1.1 min versus 28.2 4.9 min, P < 0.05; 6.7 27.1 5.0 0.05) first emetic episode and significantly decreased frequency...

10.1213/01.ane.0000130003.68288.c7 article EN Anesthesia & Analgesia 2004-09-01

We compared live/real time three‐dimensional transesophageal echocardiography (3D TEE) with real two‐dimensional (2D in the assessment of individual mitral valve (MV) segment/scallop prolapse and associated chordae rupture 18 adult patients a flail MV undergoing surgery for regurgitation. 2D TEE was able to diagnose prolapsing correctly only 9 when surgery. In three these, diagnosed an additional not confirmed at remaining nine patients, surgical findings were missed by TEE. On other hand 3D...

10.1111/j.1540-8175.2008.00832.x article EN Echocardiography 2008-10-23

Thirteen patients already scheduled for surgery repair of prosthetic paravalvular regurgitation underwent intraoperative real time two-dimensional transesophageal echocardiography (2D TEE) and live/real three-dimensional (3D TEE). In all patients, 3D TEE was able to provide more information regarding the location size defect as compared 2D TEE. resulted in a accurate localization an estimation that correlated much closely with surgical findings when Our preliminary results demonstrate...

10.1111/j.1540-8175.2009.01022.x article EN Echocardiography 2009-09-01

In Brief We report a case of permanent paraplegia in an 81-yr-old patient who had thoracic epidural catheterization performed under general anesthesia for abdominal surgery. The needle was introduced at the T9-10 interspace, and 3 passes were made to locate space with loss-of-resistance-to-air technique. During postoperative pump infusion, unaware progressive motor sensory impairment. Sensory loss below T11 no movement either lower extremity identified 8 h after Magnetic resonance imaging...

10.1213/01.ane.0000130391.62612.3e article EN Anesthesia & Analgesia 2004-08-01

Abstract Objective: To evaluate the safety and feasibility of transcatheter closure atrial septal defect (ASD) without balloon sizing. Methods: A total 243 patients (group I), aged 2.1–76 years (median 22 years), underwent ASD The maximal diameter was measured on transesophageal echocardiographic (TEE) images. size device selected generally 4–6 mm 5–8 larger than diameter, if &lt;14 ≥14 mm, respectively. results in group I were compared with those 271 II, median age 11 years) who sizing...

10.1002/ccd.21308 article EN Catheterization and Cardiovascular Interventions 2007-11-05

Background: Antioxidants effectively reduce ischemia-reperfusion (IR) injury. The cardioprotective effects of luteolin, a flavonoid that exhibits antioxidant properties and is widely available in many fruits vegetables, were examined rats subjected to myocardial IR Methods Results: Rats ischemia or reperfusion injury evaluate the antiarrhythmic luteolin. Myocardial infarct size was determined histochemically with triphenyltetrazolium chloride staining left ventricle. Luteolin administered...

10.1253/circj.cj-10-0381 article EN Circulation Journal 2010-12-20

BackgroundPerioperative monitoring of mitral valve (MV) anatomy, function, and pathology is essential for surgical management different MV disease.

10.1093/ejechocard/jep173 article EN European Journal of Echocardiography 2009-11-21

Ruptured sinus of Valsalva aneurysms (RSVA) can be associated with ventricular septal defects or isolated lesions. Surgical repair has been the traditional treatment for RSVA. The results transcatheter closure RSVA in 4 patients are reported.From 2003 to 2004, (2 males and 2 females) aged from 18 years 47 were identified. diagnosis was made based on a combination several imaging modalities. drainage site right ventricle 2, atrium remaining 2. All underwent general anesthesia transesophageal...

10.1253/circj.70.1043 article EN Circulation Journal 2006-01-01

Objectives This study assessed the ability of live/real time three‐dimensional transesophageal echocardiography (3 DTEE ) in measuring (1) atrial septal defect ( ASD maximum dimension, area, and adjacent rim size, (2) occluder left right disk (3) length contact between LA aorta, (4) assessing device related complications such as residual shunt, embolization, encroachment upon cardiac structures. Materials Methods 3DTEE images acquired during percutaneous closure by A mplatzer S eptal O...

10.1111/echo.12106 article EN Echocardiography 2013-01-22

Nausea and vomiting are major adverse effects during spinal anesthesia for cesarean delivery. Stimulation of the P6 (Neiguan) acupoint is a traditional Chinese acupuncture technique used effective antiemetic purposes. In this study, we evaluated effect acupressure in parturients randomized, double-blind, controlled trial, 110 scheduled elective delivery were enrolled study. Thirty minutes before initiation anesthesia, randomized to bands or placebo bilaterally on nausea observed over study...

10.1213/01.ane.0000195553.82409.00 article EN Anesthesia & Analgesia 2006-02-14

The combination intrathecal fentanyl (25 μg) and bupivacaine (2.5 mg) provides effective labor analgesia for approximately 90 minutes. purpose of this prospective, randomized, double-blinded investigation was to determine if the addition morphine (150 would prolong analgesia. By using combined spinal epidural technique, 95 healthy primiparous laboring women in early received 2 mL one two study solutions, either FB (n = 48): mg); or FBM 47): plus μg). mean duration significantly longer group...

10.1097/00000539-200103000-00022 article EN Anesthesia & Analgesia 2001-03-01

Implications Intraoperative transesophageal echocardiography can be useful to diagnose pulmonary venous anastomotic stenoses during lung transplantation.

10.1213/00000539-200009000-00010 article EN Anesthesia & Analgesia 2000-09-01

The combination intrathecal fentanyl (25 μg) and bupivacaine (2.5 mg) provides effective labor analgesia for approximately 90 minutes. purpose of this prospective, randomized, double-blinded investigation was to determine if the addition morphine (150 would prolong analgesia. By using combined spinal epidural technique, 95 healthy primiparous laboring women in early received 2 mL one two study solutions, either FB (n = 48): mg); or FBM 47): plus μg). mean duration significantly longer group...

10.1213/00000539-200103000-00022 article EN Anesthesia & Analgesia 2001-03-01
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