- Bipolar Disorder and Treatment
- Schizophrenia research and treatment
- Tryptophan and brain disorders
- Heart Rate Variability and Autonomic Control
- Pharmacological Effects and Toxicity Studies
- Treatment of Major Depression
- Functional Brain Connectivity Studies
- Genetics and Neurodevelopmental Disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Neurotransmitter Receptor Influence on Behavior
- Obsessive-Compulsive Spectrum Disorders
- Mental Health Research Topics
- Autism Spectrum Disorder Research
- Electroconvulsive Therapy Studies
- Epilepsy research and treatment
- Neural and Behavioral Psychology Studies
- Mental Health Treatment and Access
- Sleep and related disorders
- Attention Deficit Hyperactivity Disorder
- Child and Adolescent Psychosocial and Emotional Development
- Transcranial Magnetic Stimulation Studies
- Substance Abuse Treatment and Outcomes
- Sexual function and dysfunction studies
- EEG and Brain-Computer Interfaces
- Eating Disorders and Behaviors
Tri-Service General Hospital
2015-2024
National Defense Medical Center
2015-2024
Counseling Center
2014-2024
Tri-Service General Hospital Beitou Branch
2014-2024
Cheng Hsin General Hospital
2020
National Defense Medical College
2019
Taipei Tzu Chi Hospital
2016-2018
Far Eastern Memorial Hospital
2017
National Cheng Kung University Hospital
2016
Kaohsiung Veterans General Hospital
2015-2016
Objective:Emerging evidence suggests that inflammation and neurodegeneration underlies bipolar disorder. To investigate biological markers of cytokines brain-derived neurotrophic factor between I, II, other specified disorder with short duration hypomania may support the association inflammatory dysregulation and, more specifically, provide for patients were similar to II from a marker perspective.
<b><i>Background:</i></b> Chronic periodontitis and gingivitis are associated with various diseases; however, their impact on dementia is yet to be elucidated. This study aimed at investigating the association between chronic gingivitis, risk of developing dementia. <b><i>Methods:</i></b> A total 2,207 patients, newly diagnosed January 1, 2000 December 31, 2000, were selected from National Health Insurance Research Database Taiwan, along 6,621...
Allergic diseases, such as bronchial asthma, allergic rhinitis, atopic dermatitis, and psychiatric disorders, are major health issues. There have been reports that diseases were associated with depression or anxiety disorders. This study aimed to investigate the association between these risk of developing overall disorders in patients from Taiwan.This cohort used database Taiwan National Health Insurance Program. A total 186,588 enrolled patients, 46,647 subjects who had suffered 139,941...
Abstract There were several studies about the psychiatric and mental health issues related to severe adult respiratory syndrome (SARS) outbreak in 2003, however, association between SARS overall risk of disorders suicides has, as yet, be studied Taiwan. The aim this study is examine whether associated with suicide. A total 285 patients 2850 controls without (1:10) matched for sex, age, insurance premium, comorbidities, residential regions, level medical care, index date selected February 25...
Posttraumatic stress disorder (PTSD) is a trauma-induced mental characterized by fear extinction abnormalities, which involve biological dysfunctions among circuit areas in the brain. Oxytocin (OXT) neuropeptide that regulates sexual reproduction and social interaction has recently earned specific attention due to its role adjusting neurobiological behavioral correlates of PTSD; however, mechanism this achieved remains unclear. The present study aimed examine whether effects OXT on traumatic...
The efficacy of fronto-temporal transcranial direct current stimulation in treating auditory verbal hallucinations and other psychopathological symptoms schizophrenia patients has been examined a small number clinical trials with limited sample sizes, but the results are mixed. Fronto-temporal also demonstrated to enhance patients' insight into their mental illness an open-label pilot study. investigation aimed investigate therapeutic effects on severity hallucinations, symptoms, large...
Poor insight is prevalent in patients with schizophrenia and has been associated acute illness severity, medication non-adherence poor treatment outcomes. Paradoxically, high various undesirable outcomes, including low self-esteem, depression subjective quality of life (QoL) schizophrenia. Despite the growing body studies conducted Western countries supporting pernicious effects improved psychosis, which bases on level self-stigma, are unclear non-Western societies. The current study...
Low-dose dextromethorphan (DM) might have anti-inflammatory and neurotrophic effects mechanistically remote from an NMDA receptor. In a randomized, double-blind, controlled 12 week study, we investigated whether add-on reduced cytokine levels benefitted opioid-dependent patients undergoing methadone maintenance therapy (MMT). Patients were randomly assigned to group: DM60 (60mg/day dextromethorphan; n = 65), DM120 (120mg/day or placebo (n 66). Primary outcomes the dose required, plasma...
This study aimed to investigate the association between adults with ADHD and risk of developing dementia.Utilizing National Health Insurance Research Database Taiwan, patients were identified compared age- gender-matched controls (1:3).Of participants, 37 (5.48%) developed dementia 81 (4.0%) in control group. Cox proportional hazards regression analysis revealed that participants more likely develop dementia. The crude hazard ratio (HR) is 3.418 (95% confidence interval [CI] = [2.289,...
Introduction Children and adolescents with autism spectrum disorder (ASD) may be particularly vulnerable to the impact of traumatic events, yet association between ASD risk developing acute stress post-traumatic (PTSD) remains uncertain. This study aims investigate this association, addressing gap in large-scale evidence on subject. Methods Conducted as a retrospective matched cohort study, data was sourced from National Health Insurance Research Database (NHIRD) Taiwan, spanning January 1,...
Objective Decreased heart rate variability (HRV) has been reported in generalized anxiety disorder (GAD), but the results are mixed. Little is known about impact of comorbid major depression (MD) on HRV GAD patients. Both issues necessitate further investigation. Methods Twenty unmedicated, physically healthy patients, 20 patients with a secondary diagnosis MD, 40 MD and 60 matched controls were recruited. We used Hamilton Anxiety Rating Scale Depression to assess severity, respectively....
Decreased heart rate variability (HRV) has been proposed in bipolar disorder. To date, there no adequate study that investigated resting HRV unmedicated patients with disorder the manic state.To examine whether mania is associated decreased HRV, 61 and 183 healthy volunteers aged 20-65 years were recruited for this case-control analysis. The Young Mania Rating Scale (YMRS), Clinical Global Impression-Severity, Hamilton Depression (HAM-D), Anxiety (HAM-A) used clinical ratings. Cardiac...