- Neuroendocrine regulation and behavior
- Sexual function and dysfunction studies
- Stress Responses and Cortisol
- Obsessive-Compulsive Spectrum Disorders
- Posttraumatic Stress Disorder Research
- Eating Disorders and Behaviors
- Attention Deficit Hyperactivity Disorder
- Tryptophan and brain disorders
- Infant Health and Development
- Child Abuse and Trauma
- Diabetes and associated disorders
- Restless Legs Syndrome Research
- Neuroscience and Neuropharmacology Research
- Psychosomatic Disorders and Their Treatments
- Psychopathy, Forensic Psychiatry, Sexual Offending
- Treatment of Major Depression
- Mental Health and Psychiatry
- Attachment and Relationship Dynamics
- Smoking Behavior and Cessation
- Personality Disorders and Psychopathology
- Parkinson's Disease Mechanisms and Treatments
- Empathy and Medical Education
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Autism Spectrum Disorder Research
- Genetics and Neurodevelopmental Disorders
National Defense Medical Center
2009-2024
Tri-Service General Hospital Songshan Branch
2014-2023
Tri-Service General Hospital
2008-2021
ORCID
2021
Posttraumatic stress disorder (PTSD) is a trauma-induced mental characterized by fear extinction abnormalities, which involve biological dysfunctions among circuit areas in the brain. Oxytocin (OXT) neuropeptide that regulates sexual reproduction and social interaction has recently earned specific attention due to its role adjusting neurobiological behavioral correlates of PTSD; however, mechanism this achieved remains unclear. The present study aimed examine whether effects OXT on traumatic...
Traumatic experience may lead to various psychological sequelae including the unforgettable trauma-associated memory as seen in posttraumatic stress disorder (PTSD), with a mechanism of impaired fear extinction due biological imbalance among hypothalamic-pituitary-adrenal (HPA) axis and circuit areas such medial prefrontal cortex (mPFC), hippocampus, amygdala. Recently sociability PTSD patients received great attention involvement oxytocin (OXT) mediation is worth being investigated. This...
Inflammation has been considered important in the pathogenesis of schizophrenia. Increasing evidence reveals that patients with schizophrenia have abnormal expression cytokines, which are related to development metabolic abnormalities. Metabolic abnormality become a critical issue, though its longitudinal relationship disorder, such as antipsychotics influence, is unclear. We aimed investigate whether abnormalities parameters and cytokine levels acute exacerbated schizophrenic existed,...
Somnambulism consists of variously complex behaviors that may result in harm to self or others. Many different medications have been reported induce somnambulism, and a few them are newer antidepressants. A 40-year-old woman with history major depression who experienced new onset somnambulism for successive 3 nights, whereas the antidepressant mirtazapine was increased from 30 45 mg/d. The notable sleepwalking symptoms terminated dramatically on first night after withdrawal mirtazapine....
Abstract Background This study aimed to investigate the association between posttraumatic stress disorder and risk of developing erectile dysfunction. Methods In this population-based retrospective cohort study, we used Taiwan’s National Health Insurance Research Database analyze patients who were newly diagnosed with (PTSD) 2000 2013, a 1:3 ratio by age index year matched in non-PTSD comparison group, for Results total, 5 out 1079 PTSD group developed dysfunction, 3 3237 (47.58 vs. 9.03 per...
Bipolar disorder (BD) and attention-deficit/hyperactivity (ADHD) have been associated with the use of cigarettes, but little is known about impact subthreshold symptoms BD or ADHD on course nicotine dependence. Identifying links essential for elucidating pathway supporting development prevention strategies adolescents.Participants (n = 3322) aged 15-17 years completed Chinese version Self-Report Scale Mood Disorder Questionnaire. The modified Fagerström Tolerance Questionnaire was to measure...
Objectives: Methylphenidate (MPH) is highly effective in controlling the symptoms of attention-deficit/hyperactivity disorder (ADHD), but some children with ADHD either do not respond to, or tolerate, treatment. Dextromethorphan (DM) a neuroprotective agent which has been used treatment neuropsychiatric disorders. This clinical trial had examined effect DM on use MPH ADHD. Methods: randomized double-blind evaluated 44 male outpatients, aged between 6 and 12 years, diagnosis The study...
Abstract BACKGROUND: This study aimed to investigate the association between posttraumatic stress disorder and risk of developing erectile dysfunction. METHODS: In this population-based, retrospective cohort study, we used Taiwan’s National Health Insurance Research Database analyze patients who were newly diagnosed with (PTSD) 2000 2013, a 1:3 ratio by age, index year matched in non-PTSD comparison group, for RESULTS: total, five out 1,079 PTSD developed dysfunction, three 3,237 group...