A5036236318- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Cardiovascular and exercise physiology
- Dementia and Cognitive Impairment Research
- Transcranial Magnetic Stimulation Studies
- Obstructive Sleep Apnea Research
- Neonatal Respiratory Health Research
- Non-Invasive Vital Sign Monitoring
- Heart Rate Variability and Autonomic Control
- Long-Term Effects of COVID-19
- Neural and Behavioral Psychology Studies
- COVID-19 and Mental Health
- Alzheimer's disease research and treatments
- Neurogenetic and Muscular Disorders Research
- Intensive Care Unit Cognitive Disorders
- Asthma and respiratory diseases
- Cystic Fibrosis Research Advances
- Cardiac Arrest and Resuscitation
- Attention Deficit Hyperactivity Disorder
- Physical Education and Gymnastics
- Cardiac Health and Mental Health
- Amyotrophic Lateral Sclerosis Research
- Angiogenesis and VEGF in Cancer
- Neurological Disease Mechanisms and Treatments
- Youth, Drugs, and Violence
Universidade Federal de Santa Catarina
2015-2024
Sunnybrook Hospital
2019-2024
Sunnybrook Research Institute
2017-2024
University of Toronto
2023-2024
Sunnybrook Health Science Centre
2017-2024
Polydoro Ernani de São Thiago University Hospital
2024
Universidad Mariana
2023
Ministério da Saúde
2023
Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina
2023
National Council for Scientific and Technological Development
2009-2023
<h3>Importance</h3> Apathy, characterized by diminished will or initiative and one of the most prevalent neuropsychiatric symptoms in individuals with Alzheimer disease, is associated significant caregiver burden, excess disability, increased medical costs, mortality. <h3>Objective</h3> To measure whether methylphenidate compared placebo decreases severity apathy disease. <h3>Design, Setting, participants</h3> This multicenter randomized placebo-controlled clinical trial was conducted from...
OBJETIVO: Descrever o padrão respiratório e movimento toracoabdominal de indivíduos saudáveis considerando a idade sexo. MÉTODOS: Foram estudados 104 com idades entre 20-39, 40-59 60-80 anos, 41 homens 63 mulheres, índice massa corporal valores espirométricos normais. A pletismografia respiratória por indutância foi utilizada para mensurar, durante repouso em decúbito dorsal, as seguintes variáveis: volume corrente (Vc), frequência (f), ventilação minuto (VE), razão tempo inspiratório total...
Optoelectronic plethysmography (OEP) is an innovative method of indirect measurement pulmonary ventilation, capable breath-by-breath, three-dimensional, real time assessment absolute lung volumes and their variations in the three compartments chest wall (pulmonary rib cage, abdominal abdomen). OEP allows variables breathing pattern, asynchrony, contribution each compartment hemithorax to tidal volume.To review literature on following aspects related OEP: history, operating principle,...
This study compared the passive stiffness of wrist flexors and strength extensors in three different positions (30 degrees flexion, neutral, 30 extension) between children with cerebral palsy (CP) typically developing (TD) comparison children. It also examined associations these characteristics manual function CP. Eleven spastic hemiplegic CP (six females, five males; mean age 8y 5mo [SD 1y 8mo], range 6-11y) 11 TD children, matched for sex, took part this study. Passive muscles was measured...
Eccentric cycling may present an interesting alternative to traditional exercise rehabilitation for patients with advanced COPD, because of the low ventilatory cost associated lengthening muscle actions. However, due damage and soreness typically eccentric exercise, there has been reluctance in using this modality clinical populations. This study assessed feasibility applying protocol, based on progressive overload, six severe COPD aim minimizing side effects maximizing compliance. Over 5...
BACKGROUND: The mechanisms underlying breathing exercises have not been fully elucidated. OBJECTIVES: To evaluate the impact of four on (diaphragmatic breathing, inspiratory sighs, sustained maximal inspiration and intercostal exercise) pattern thoracoabdominal motion in healthy subjects. METHOD: Fifteen subjects both sexes, aged 23±1.5 years old with normal pulmonary function tests, participated study. were evaluated using optoelectronic plethysmography system a supine position trunk...
Optoelectronic plethysmography (OEP) has been used to measure changes in chest wall volume and its compartments. However, literature lacks research on reliability. The purpose of this study was evaluate the intra-rater inter-rater reliability OEP. Thirty-two healthy subjects were evaluated at rest during submaximal exercise a cycle ergometer. following variables assessed: (VCW); percentage contribution pulmonary rib cage (V(rcp)%), abdominal (V(rca)%), (V(rc)%) abdomen (Vab%); end-expiratory...
Chest wall volumes and breathing patterns of 13 male COPD patients were evaluated at rest during inspiratory loaded (ILB). The sternocleidomastoid (SMM) abdominal muscle activity was also evaluated. main compartment responsible for the tidal volume ILB abdomen. During exhibited, in addition to increases ratio time total respiratory cycle minute ventilation, (p<0.05) chest by an increase abdomen as a result improvement end without changing on expiratory volume. SMM increased 63.84% 1.94% ILB....
The effects of non-invasive ventilation (NIV) on the breathing pattern and thoracoabdominal motion patients with amyotrophic lateral sclerosis (ALS) are unknown.1) To analyze influence NIV chest wall volumes assessed by optoelectronic plethysmography in ALS 2) to compare these parameters supine sitting positions those healthy individuals (without NIV).Nine were evaluated position using NIV. In addition, nine both positions. Statistical analysis was performed paired Student t-test or Wilcoxon...
The measurement of maximal respiratory pressure (MRP) is a procedure widely used in clinical practice to evaluate muscle strength through the inspiratory (P(Imax)) and expiratory (P(Emax)). Its applications include diagnostic procedures evaluating responses interventions. However, there great variability equipment procedures. Understanding impacts characteristics different interfaces can augment repeatability this method help establish applicable predictive equations. aim study was influence...
While transcranial direct current stimulation (tDCS) can enhance aspects of memory in patients with mild cognitive impairment (MCI) and Alzheimer disease (AD), there has been wide variability both the placement tDCS electrodes treatment response. This study compared effects bifrontal (anodal over dorsolateral prefrontal cortices), bitemporal temporal sham on performance MCI AD.Seventeen diagnosed or AD received 3 sessions anodal (bifrontal, bitemporal, 2 mA for 20 minutes; sham) random...
INTRODUÇÃO E OBJETIVO: O teste de esforço com protocolo rampa é descrito como o que mais se adéqua à condição física indivíduos insuficiência cardíaca (IC). Porém, não há padronização descrita sobre incrementos velocidade e inclinação. Este estudo teve objetivo descrever resultados encontrados a partir da aplicação um adaptado para IC, classes II III New York Heart Association (NYHA). MÉTODOS: 41 média idade 46,37 ± 8,98 anos fração ejeção 31,51 9,45% fizeram análise gases expirados em...
Background: The manovacuometer is a simple and non-invasive test to measure respiratory muscle strength. Guidelines recommend the use of digital due its high accuracy. Aims: purpose this study was assess test-retest reliability concurrent validity developed at Federal University Minas Gerais (UFMG, Belo Horizonte, Brazil). Methods: 30 healthy subjects were assessed (20-30 years old, normal body mass index pulmonary function) using UFMG MicroRPM ® (Micro Medical, UK). following variables...
BackgroundPrevious trials have shown improvements in both apathy and cognition with methylphenidate (MPH).ObjectivesTo assess whether changes correlated the Apathy Dementia Methylphenidate Trial 2 (ADMET 2).ParticipantsMild to moderate AD patients clinically significant randomized MPH (20 mg/day) or placebo for 6 months.MeasurementsApathy was measured Neuropsychiatric Inventory-apathy (NPI-A) domain. Cognition using Mini-Mental State Exam (MMSE), Hopkins Verbal Learning (immediate [HVLT-I],...
OBJETIVO: Avaliar a influência das posições prona e supina em recém-nascidos prematuros pós-síndrome do desconforto respiratório, respirando espontaneamente estado de sono ativo, sobre variáveis padrão movimento toracoabdominal saturação periférica da hemoglobina pelo oxigênio. MÉTODOS: Estudo quase experimental. Doze com peso > 1.000 g no momento estudo foram estudados nas duas posições, ordem randomizada. A pletismografia respiratória por indutância foi utilizada para avaliação...
FUNDAMENTO: O limiar anaeróbico (LA) fornece informações sobre a capacidade funcional na insuficiência cardíaca (IC). Porém, determinação visual do LA por métodos ventilatórios é subjetiva, ficando suscetível à diferença entre examinadores. OBJETIVOS: Avaliar reprodutibilidade intraexaminador e interexaminadores em indivíduos com IC leve moderada pelos visual-gráfico V-slope. Comparar correlacionar os resultados encontrados. MÉTODOS: Após realização de teste ergoespirométrico esteira,...
Abstract Background Transcranial direct current stimulation (tDCS) is a non-invasive type of brain that uses electrical currents to modulate neuronal activity. A small number studies have investigated the effects tDCS on cognition in patients with Mild Cognitive Impairment (MCI) and Alzheimer’s disease (AD), demonstrated variable effects. Emerging evidence suggests most effective when applied active circuits. Aerobic exercise known increase cortical excitability improve network connectivity....