Background: Flap necrosis caused by inadequate blood supply is a common postoperative complication in reconstructive surgery. Because putative stem cell population within the adipose tissue has been found to possess angiogenic potential, authors sought determine whether these cells might selectively induce neovascularization and increase viability of random pattern skin flaps. Methods: Adipose-derived were isolated from inguinal fat pads ICR mice expanded ex vivo for three passages. After...

A number of surgical techniques have been developed to promote periodontal tissue regeneration. Bone marrow–derived stem cells also shown In this study, we sought determine whether adipose-derived (ASCs) can regeneration as well. ASCs were isolated from a Wistar rat, passaged twice, mixed with platelet-rich plasma (PRP) obtained inbred rats, and implanted into the defect that had generated in test rats. Tissue specimens harvested after 2, 4, 8 weeks for histological analysis. Rats received...

Objective: The relationship between the wound contraction and levels of α-smooth muscle actin (α-SMA) has been revealed in different studies. We aimed to investigate effects mesenchymal stem cells (MSCs), mainly bone-marrow-derived (BSCs) adipose-derived (ASCs), find out α-SMA, fibroblast growth factor (FGF), transforming beta, vascular endothelial (VEGF) on an vivo acute healing model after application MSCs. Approach: Four circular skin defects were formed dorsum Fisher rats (n=20). applied...

Plastic surgeons have sought to improve nasolabial folds, jowls, jaw lines, and cervical contour with face-lifting procedures that are abundant in the literature. The retaining ligaments of face support facial soft tissue normal anatomic position, resisting gravitational change. As this ligamentous system attenuates, fat descends into plane between superficial deep fascia, stigmata age develop. In study, surgical correction plication musculoaponeurotic (SMAS) reposition structures descended...

Background: Advances in the treatment of reperfusion injury have created an opportunity for plastic surgeons to apply these treatments flaps and implanted tissues. The authors examined direct indirect effects adipose-derived stem cells on ischemia-reperfusion a skin flap model determine vivo differentiation endothelial cells; levels vascular growth factor (VEGF), transforming factor-β, fibroblast factor; ultrastructural changes apparent with scanning electron microscopy clarify initial...

Background: Perforator flaps, now used in various parts of the body, serve as a crucial option for reconstruction defects hand region, often caused by tumor resections, trauma, or burns. Understanding anatomy perforators allows design flaps closer to defect, improving tissue compatibility without requiring sacrifice major arteries. Methods: The study was conducted on 22 hands from 11 cadavers fixed 10% formaldehyde solution. radial and ulnar arteries were dissected distal third forearm....

Color and texture match is crucial in reconstruction of facial tissue defects. Between March 1997 July 2000, island flaps based on the parietal, anterofrontal, centrofrontal, posterofrontal, superior auricular branches superficial temporal artery were used defects localized different regions face 28 patients. According to size location defect, flap was selected. There 15 male patients 13 female patients, with ages ranging between 19 74 years. In six flaps, venous congestion observed. Because...

Cesarean scar pregnancy is a very rare form of and life-threatening situation. It has become an important serious problem over the last 10 years, as result worldwide increase in cesarean births. In this retrospective series, diagnosis pregnancy, management, treatment methods, risk factors, possibility subsequent normal are discussed, case descriptions presented.

High-flow nasal cannula therapy has been shown to be useful in the treatment of patients with acute respiratory failure caused by severe syndrome-coronavirus disease-2. The ROX index can help predict success high-flow coronavirus disease-19-related failure. However, timing ROX- assessment is still unclear protect from complications due early or delayed intubation.To evaluate relation between patterns within first 48 hours and rates. secondary aim was determine other possible predictors...

Background: Cross-face nerve grafting combined with functional muscle transplantation has become the standard in reconstructing an emotionally controlled smile complete irreversible facial palsy. However, efficacy of this procedure depends on ability regenerating axons to breach two coaptations and reinnervate endplates denervated muscle. The current study tested hypothesis that adipose-derived stem cells would enhance axonal regeneration through a cross-facial graft thereby recovery...

In Brief The split-thickness skin graft (STSG) donor sites have been treated with various and plenty of dressing techniques materials. An ideal STSG site should antibacterial, hemostatic, promoting epidermal healing properties. We performed a prospective study to evaluate the effect oxidized regenerated cellulose on healing. Between January 2002 2005, 40 patients who were operated in any kind reconstructive operations included study. One half wound was covered other same patient fine mesh...

In Brief The main aim of the treatment fingertip amputations with no indication replantation was to establish functional and esthetic construction. critical point in utilization bone nail tissue as a graft for reconstruction choose flap that is sufficiently vascular nourish these grafts. We have performed homodigital artery flaps cover nailbed grafts taken from amputation restore function an acceptable result. venous insufficiency increased probability failure should be into consideration....

Angiogenetic potential has been reported for bone marrow-derived stem cells (BSCs) and adipose-derived (ASCs). The superficial femoral artery, vein, fascia were used as a vascular crane prefabrication model of skin graft to flap. BSCs or ASCs injected before the adaptation depending on group. prefabricated grafts then transferred inguinal region in every 7 days observe viability. In experiment part I (n = 18), critical time was found be 1 week. II 12), control assays performed same animal...

Plastic surgeons have sought to improve nasolabial folds, jowls, jaw lines, and cervical contour with face-lifting procedures that are abundant in the literature. The retaining ligaments of face support facial soft tissue normal anatomic position, resisting gravitational change. As this ligamentous system attenuates, fat descends into plane between superficial deep fascia, stigmata age develop. In study, surgical correction plication musculoaponeurotic (SMAS) reposition structures descended...