A5080812533- Blood Pressure and Hypertension Studies
- Cardiovascular Health and Disease Prevention
- Heart Rate Variability and Autonomic Control
- Nutrition and Health Studies
- Thermoregulation and physiological responses
- Diabetes and associated disorders
- Diabetes Management and Research
- Cardiovascular and exercise physiology
- Cerebrovascular and Carotid Artery Diseases
- Hormonal Regulation and Hypertension
- Cardiovascular Syncope and Autonomic Disorders
- Acute Ischemic Stroke Management
- Cardiovascular Disease and Adiposity
- Systemic Sclerosis and Related Diseases
- Venous Thromboembolism Diagnosis and Management
- Traumatic Brain Injury and Neurovascular Disturbances
- Infrared Thermography in Medicine
- Obstructive Sleep Apnea Research
- Social Issues in Poland
- Diet and metabolism studies
- Hemodynamic Monitoring and Therapy
- Climate Change and Health Impacts
- Polish Legal and Social Issues
- Nutritional Studies and Diet
- Circadian rhythm and melatonin
Gdańsk Medical University
2014-2024
Gdańsk University of Technology
2016
Nicolaus Copernicus University
2016
Tottori University
2005
Mayo Clinic
2005
University of Iowa
2005
WinnMed
2005
University of Gdańsk
2004
Huta Stalowa Wola (Poland)
2004
Kyoto Pharmaceutical University
2004
The mechanisms mediating the more striking age related increase in cardiovascular disease women than men are poorly understood. We tested hypothesis that aging has a greater impact on sympathetic traffic men. Muscle nerve activity (MSNA), blood pressure, and heart rate were measured 120 healthy males 96 females aged 20 to 72 years. MSNA increased with both sexes, but explained 53% of variance female subjects only 8% male subjects. Both slope intercept regression lines significantly different...
A wide range of definitions is used to distinguish subjects in whom blood pressure (BP) falls at night (dippers) from their counterparts (nondippers). In an attempt standardize the definition nondipping, we determined nocturnal BP fall and night-day ratio by 24-hour ambulatory monitoring 4765 normotensive 2555 hypertensive 10 99 years old. all combined, systolic/diastolic corresponding averaged (+/- SD) -16.7 +/- 11.0/ -13.6 8.1 mm Hg 87.2 8.0%/83.1 9.6%, respectively. subjects, 95th...
Carotid-femoral pulse wave velocity (PWV) has been shown to be a powerful predictor of cardiovascular morbidity and mortality. Sympathetic neural mechanisms may have stiffening influence on arterial mechanical properties. The relationship between direct measures sympathetic traffic PWV in healthy humans not previously studied. We, therefore, tested the hypothesis that is independently linked muscle nerve activity (MSNA) normal individuals.We measured MSNA (microneurography), (Complior...
Off-label treatment is the use of a drug approved for marketing, outside registration in terms indication, age group, dose or route administration. Despite constant appearance new preparations on market, SmPCs guidelines current clinical problem. It believed that it based needs patients unmet by classical therapy methods. This work focuses off-label inflammatory dermatoses such as atopic dermatitis, psoriasis, acne vulgaris and rosacea. Publications this subject, available PubMed, Google...
Pulsatility index (PI) is defined as the difference between peak systolic flow and minimum diastolic velocity, divided by mean velocity recorded throughout cardiac cycle. It a non-invasive method of assessing vascular resistance with use Doppler ultrasonography. was first introduced in 1974 Gosling King also known Index. PI examining macrocirculation has variety clinical applications. For instance, diabetic patients, it been measured on common carotid, middle cerebral or renal arteries to...
Although headache is regarded a symptom of hypertension, its relation to blood pressure, especially in mild and moderate not clear. Thus, the aim study was investigate whether patients with hypertension may be attributed simultaneous elevations pressure.Ambulatory pressure monitoring (ABPM) performed (mean age 48 +/- 10 years, n = 150, 92 men, 58 women) classified, according their office as stage 1 -2 hypertensives (JNC VI). Headache periods were recorded patients' diaries.Headaches...
OBJECTIVE Cerebrovascular reactivity impairment was reported as a marker of cerebral microangiopathy in long-term type 1 diabetes. Intima-media complex thickening reflects early stages macroangiopathy The analysis the relationship between these variables and other microangiopathic complications might serve beneficial indicator for prophylaxis patients. RESEARCH DESIGN AND METHODS Vasomotor reserve (VMRr) breath-holding index (BHI) middle artery were measured with transcranial Doppler 59...
Metabolic memory refers to the long-term effects of achieving early glycemic control and adverse implications high blood glucose levels, including development progression diabetes complications. Our study aimed investigate whether phenomenon metabolic plays a role in immune profile young patients with uncomplicated type 1 (T1D). The group included 67 mean age 15.1 ± 2.3 years minimum disease duration 1.2 years. consisted 27 healthy children adolescents Patients were divided into three groups...
This study aimed to evaluate the earliest changes in structure and function of peripheral microcirculation using capillaroscopy transcutaneous oxygen pressure measurement children adolescents with type 1 diabetes mellitus at baseline during post-occlusive reactive hyperemia (PORH) duration. Sixty-seven patients (T1D), aged 8 18 years, twenty-eight age- sex-matched healthy subjects were included analysis. Diabetic divided into subgroups based on median disease The differed chronological age,...
Introduction. Insomnia may increase risk of cardiovascular events. There is little data available reporting the prevalence and clinical relevance insomnia in patients with essential hypertension. Therefore, aim study was to investigate relationship between different biochemical parameters hypertension patients. Methods. Four hundred thirty‐two (mean age: 47±13 years; 253 male, 179 female) were screened for using Athens Scale (AIS). Several variables including age, sex, known duration...
The aim of our study was to evaluate the vasodilatory effect l-arginine infusion on skin microcirculation and assess relationship between this presence microangiopathy in patients with type 1 diabetes.Capillaroscopy performed before after 48 diabetic (26 women 22 men; age, 39.8 ± 6.3 years) 24 volunteers free any chronic disease (13 11 38.0 6.7 years). reactivity, as expressed by percentage area covered capillaries (coverage) distance (distance), reactivity microangiopathic complications...
We evaluated the relationship between pretreatment IL-6 and hsCRP levels, symptom severity functional outcome of patients with acute ischemic stroke (AIS) treated IV-thrombolysis.IL-6 samples were obtained from 83 consecutively Caucasian AIS prior to initiation IV-thrombolysis. Severity symptoms was assessed using National Institutes Health Stroke Scale (NIHSS), whereas modified Rankin (mRS). The commercially available sets enzymatic immune tests used estimate concentrations inflammatory...
Smoking is an important risk factor for cardiovascular disease. Sympathetic responses to cigarette smoking may be implicated in the link between and We tested hypothesis that sympathetic neural are age dependent.We examined effects of sham on muscle nerve activity, blood pressure heart rate 14 normotensive middle-aged (49 +/- 4 years) 12 young (29 habitual smokers matched body mass index (25 2 kg/m2 both groups).Sham had no significant effect drive, or either group. Cigarette increased...
Acute hypoxia exerts strong effects on the cardiovascular system. Heart-generated pulsatile cerebrospinal fluid motion is recognised as a key factor ensuring brain homeostasis. We aimed to assess changes in heart-generated coupling between blood pressure (BP) and subarachnoid space width (SAS) oscillations during hypoxic exposure.Twenty participants were subjected controlled decrease oxygen saturation (SaO2 = 80%) for five minutes. BP heart rate (HR) measured using continuous finger-pulse...
Obstructive sleep apnea (OSA) is associated with elevated risk of cardiovascular events. The early stages vascular complications can be visualized by means ultrasound. Intima-media thickness (IMT) correlates the presence factors diseases such as hypertension, diabetes, tobacco smoking, or hyperlipidemia. However, little known whether OSA itself may cause IMT thickening. study group was composed 28 patients (6 women, 22 men; mean age = 53.8 years, BMI 27.1 kg/m2, AHI 22.4/h) who had no...
The sense of coherence is a tool for confronting the challenges posed by life. It constitutes general human orientation, which expressed through conviction that outside stimuli can be explained; there are resources allowing people to cope with coming perceived as worthwhile involvement. created based on three correlated elements: comprehensibility, manageability, and meaningfulness.The aim this study establish level among nursing managers, compare results found in other groups employees,...
The aim of this study was to analyze the relationship between immunological markers and dysfunction cutaneous microcirculation in young patients with type 1 diabetes. group consisted 46 diabetes no associated complications. Microvascular function assessed use nail fold capillaroscopy before after implementing post-occlusive reactive hyperemia. This evaluation then repeated 12 months. Patients were divided into two subgroups according their baseline median coverage (defined as ratio capillary...
Abstract The U.S. Food and Drug Administration designed the trough-to-peak ratio as an instrument for evaluation of long-acting antihypertensive drugs, but ratios are usually reported without accounting interindividual variability. This study investigated how would be affected by intraindividual variability smoothing diurnal blood pressure profiles. ambulatory was recorded on placebo in 143 hypertensive patients (diastolic conventional measurement >95 mm Hg). After 2 months, recordings...