A5071444345- Gold and Silver Nanoparticles Synthesis and Applications
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
- Advanced biosensing and bioanalysis techniques
- Nanoparticles: synthesis and applications
- Plasmonic and Surface Plasmon Research
- Biosensors and Analytical Detection
- Photoacoustic and Ultrasonic Imaging
- Nanocluster Synthesis and Applications
- Nanomaterials for catalytic reactions
- Extracellular vesicles in disease
- Microfluidic and Bio-sensing Technologies
- Advanced Nanomaterials in Catalysis
- Protein Interaction Studies and Fluorescence Analysis
- Advanced Sensor and Energy Harvesting Materials
- RNA Interference and Gene Delivery
- Quantum Dots Synthesis And Properties
- Dendrimers and Hyperbranched Polymers
- Conducting polymers and applications
- Advanced Biosensing Techniques and Applications
- Orbital Angular Momentum in Optics
- Luminescence and Fluorescent Materials
- Surface Modification and Superhydrophobicity
- Random lasers and scattering media
- Advanced Cellulose Research Studies
Nanjing Institute of Technology
2024
University of Memphis
2015-2024
Guilin University of Technology
2022-2024
Taizhou University
2024
Dalian Medical University
2020-2023
Memphis Health Center
2015-2020
State Key Laboratory of Chemobiosensing and Chemometrics
2015-2017
Hunan University
2015-2017
Dongfeng General Hospital
2014
Hubei University of Medicine
2014
Due to strong electric fields at the surface, absorption and scattering of electromagnetic radiation by noble metal nanoparticles are strongly enhanced. These unique properties provide potential designing novel optically active reagents for simultaneous molecular imaging photothermal cancer therapy. It is desirable use agents that in near-infrared (NIR) region spectrum minimize light extinction intrinsic chromophores native tissue. Gold nanorods with suitable aspect ratios (length divided...
Noble metal nanostructures attract much interest because of their unique properties, including large optical field enhancements resulting in the strong scattering and absorption light. The enhancement photothermal properties noble nanoparticles arises from resonant oscillation free electrons presence light, also known as localized surface plasmon resonance (LSPR). can either radiate light (Mie scattering), a process that finds great utility imaging fields, or be rapidly converted to heat...
Currently a popular area in nanomedicine is the implementation of plasmonic gold nanoparticles for cancer diagnosis and photothermal therapy, attributed to intriguing optical properties nanoparticles. The surface plasmon resonance, unique phenomenon (noble metal) leads strong electromagnetic fields on particle consequently enhances all radiative such as absorption scattering. Additionally, strongly absorbed light converted heat quickly via series nonradiative processes. In this review, we...
Gold nanoparticles with unique optical properties may be useful as biosensors in living whole cells. Using a simple and inexpensive technique, we recorded surface plasmon resonance (SPR) scattering images SPR absorption spectra from both colloidal gold conjugated to monoclonal anti-epidermal growth factor receptor (anti-EGFR) antibodies after incubation cell cultures nonmalignant epithelial line (HaCaT) two malignant oral lines (HOC 313 clone 8 HSC 3). Colloidal are found dispersed...
Noble metal nanoparticles are capable of confining resonant photons in such a manner as to induce coherent surface plasmon oscillation their conduction band electrons, phenomenon leading two important properties. Firstly, the confinement photon nanoparticle's dimensions leads large increase its electromagnetic field and consequently great enhancement all radiative properties, absorption scattering. Moreover, by photon's wavelength small dimensions, there exists enhanced imaging resolving...
Human oral cancer cells are found to assemble and align gold nanorods conjugated anti-epidermal growth factor receptor (anti-EGFR) antibodies. Immnoconjugated nanospheres were shown previously exhibit strong Rayleigh (Mie) scattering useful for imaging. In the present letter, molecules near on give a Raman spectrum that is greatly enhanced (due high surface plasmon field of nanorod assembly in which their extended fields overlap), sharp homogeneous environment), polarized anisotropic...
Laser photothermal therapy of cancer with the use gold nanoparticles immunotargeted to molecular markers on cell surface has been shown be an effective modality selectively kill cells at much lower laser powers than those needed for healthy cells. To elucidate minimum light dosimetry required induce death, destruction two cancerous lines and a noncancerous line treated antiepidermal growth factor receptor (anti-EGFR) antibody-conjugated is studied, numerical heat transport model used...
The targeted delivery of nanoparticles to solid tumors is one the most important and challenging problems in cancer nanomedicine, but detailed mechanisms design principles are still not well understood. Here we report quantitative tumor uptake studies for a class elongated gold nanocrystals (called nanorods) that covalently conjugated tumor-targeting peptides. A major advantage using as "tracer" accumulated other organs can be quantitatively determined by elemental mass spectrometry (gold...
Photo-thermal therapy (PTT) is a minimally-invasive in which photon energy converted into heat to kill cancer. Gold nanoparticles absorb light strongly and convert quickly efficiently, thereby making them superior contrast agents for PTT. This gold nanoparticle-assisted PTT called PPTT has showed great popularity success recent years. The present review starts with the outline of optical properties that base followed by description synthesis several gold-based have been used including...
Resonant electron oscillations on the surface of noble metal nanoparticles (Au, Ag, Cu) create plasmon resonance (SPR) that greatly enhances absorption and Rayleigh (Mie) scattering light by these particles. By adjusting size shape particles from spheres to rods, SPR can be tuned visible near-infrared region (NIR) where biologic tissues are relatively transparent. Further, gold nanorods enhance Raman adsorbed molecules. These unique properties make especially attractive as optical sensors...
Exosomes are a potential source of cancer biomarkers. Probing tumor-derived exosomes can offer non-invasive way to diagnose cancer, assess progression, and monitor treatment responses. Novel molecular methods would facilitate exosome analysis accelerate basic clinical research. Methods: A standard gold-coated glass microscopy slide was used develop miniaturized affinity-based device capture in target-specific manner with the assistance low-cost 3-D printing technology. Gold nanorods coated...
Abstract Background and Objective Laser photothermal therapy (PTT) is practiced at the moment using short laser pulses. The use of plasmonic nanoparticles as contrast agents can decrease energy by optical property improve tumor selectivity molecular probes on particle surface. In this study, we aim selective efficient PTT exploiting nonlinear properties aggregated spherical gold conjugated to anti‐epidermal growth factor receptor (anti‐EGFR) antibodies NIR Study Design/Materials Methods...
The carbon layer and iron of magnetic carbons play an important role in Cr(<sc>vi</sc>) removal from solutions with initial pH 7 2.
Nanotechnology-based photothermal therapy has emerged as a promising treatment for cancer during the past decade. However, heterogeneous laser heating and limited light penetration can lead to incomplete tumor cell eradication. Here, we developed method overcome these limitations by combining chemotherapy with using paclitaxel-loaded gold nanorods. Paclitaxel was loaded nanorods high density (2.0 × 10(4) paclitaxel per nanorod) via nonspecific adsorption, followed stabilization poly(ethylene...
We present the synthesis and application of a new type dual magnetic plasmonic nanostructures for magnetic-field-guided drug delivery combined photothermal photodynamic cancer therapy. Near-infrared-absorbing gold nanopopcorns containing self-assembled iron oxide cluster core were prepared via seed-mediated growth method. The hybrid are superparamagnetic show great conversion efficiency (η = 61%) under near-infrared irradiation. Compact stable nanocomplexes photothermal–photodynamic therapy...
Magnetic–plasmonic core–shell nanomaterials offer a wide range of applications across science, engineering, and biomedical disciplines. However, the ability to synthesize understand magnetic–plasmonic nanoparticles with tunable sizes shapes remains very limited. This work reports experimental computational studies on synthesis properties iron oxide–gold three different (sphere, popcorn, star) controllable (70 250 nm). The were synthesized via seed-mediated growth method in which newly formed...
This review introduces and discusses synthetic approaches, magnetic optical properties of iron oxide–gold core–shell nanoparticles in different shapes.