A5068066174- Sulfur-Based Synthesis Techniques
- Organoselenium and organotellurium chemistry
- Chemical Synthesis and Reactions
- Synthesis and Catalytic Reactions
- Radical Photochemical Reactions
- Multicomponent Synthesis of Heterocycles
- Asymmetric Synthesis and Catalysis
- Synthesis and biological activity
- Synthesis and Biological Evaluation
- Catalytic Cross-Coupling Reactions
- Crystallization and Solubility Studies
- Vanadium and Halogenation Chemistry
- Selenium in Biological Systems
- Organoboron and organosilicon chemistry
- Organic Chemistry Cycloaddition Reactions
- Synthesis of Indole Derivatives
- Polyoxometalates: Synthesis and Applications
- X-ray Diffraction in Crystallography
- Catalytic C–H Functionalization Methods
- Pesticide Residue Analysis and Safety
- Catalytic Alkyne Reactions
- Genetics, Aging, and Longevity in Model Organisms
- Axial and Atropisomeric Chirality Synthesis
- Phenothiazines and Benzothiazines Synthesis and Activities
- Antibiotics Pharmacokinetics and Efficacy
Universidade Federal do Pampa
2016-2024
Universidade Federal de Santa Catarina
2009-2023
Universidade Federal do Rio Grande do Sul
2021
University of Perugia
2014
Universidade Federal de Santa Maria
2008
Universidade de São Paulo
2008
Key aspects for the development of a greener synthesis and use organoselenium compounds.
Herein, we describe a solvent- and metal-free method for the synthesis of 3-chalcogenyl-indoles from indoles diorganyl dichalcogenides using an equivalent amount DMSO as oxidant, under catalysis by molecular iodine. This mild eco-friendly approach allowed preparation wide range 3-selenyl- 3-sulfenyl-indoles in good to excellent yields.
Herein, we report a solvent- and metal-free methodology for the alkoxy-chalcogenylation of styrenes, using molecular iodine as catalyst, DMSO stoichiometric oxidant, different nucleophiles under microwave irradiation. This eco-friendly approach afforded desired products in good to excellent yields only 10 min. In addition, same protocol, carried out cyclization reaction relevant molecules, such lapachol derivatives.
We have developed a green and efficient protocol for the chalcogenation of bicyclic arenes by using I 2 /DMSO as catalytic system under solvent‐ metal‐free conditions. This allows access to several chalcogenated through C(sp )–H bond functionalization, in good excellent yields microwave irradiation or conventional heating.
Herein, we report an efficient, quick and eco-friendly new method for the synthesis of a variety selenol esters. This novel solvent-free methodology gave good to excellent isolated yields desired products after just 2 min under microwave irradiation. Furthermore, by using same green approach, were also able synthesize selenocarbonates bearing interesting functionalities.
Abstract The preparation of biologically relevant 3‐selenylindoles by a greener protocol using catalytic amount K 2 CO 3 and ethanol as biosolvent in system open to air was explored. Through this easy approach, with different functionalities were obtained good yields radical pathway.
Herein, we report a new and solvent-free methodology for the preparation of vinyl thioethers from terminal alkynes thiols, using magnetite (Fe3O4) nanoparticles as recyclable catalyst. With this greener method, desired were achieved in good yields with stereoselectivity. In addition, catalyst was easily recovered simple external magnet reused further catalytic reactions without significant loss activity up to fifth cycle.
Abstract We report an efficient, fast, and environmentally friendly method for the synthesis of a wide range thiol esters using stable diorganoyl disulfides acyl chlorides, CuO nanoparticles [pmim]Br as reductive system. This gave good to excellent isolated yields desired products after only three minutes microwave irradiation. Furthermore, by same green approach, we were also able synthesize thiocarbonates bearing interesting functionalities.
Abstract Background A liquid chromatography (LC) stability-indicating method was developed and validated for the quantitative determination of bilastine in coated tablets. Objective The procedure specificity, linearity, robustness, precision, accuracy. Plackett-Burmann experimental design used to determine robustness method. Method Chromatographic separation performed on a Shim-pack® RP-18 column with fluorescence detection. degradation products formed under oxidative conditions were...
Background: In this review we focus on the environmentally friendly processes used for preparation of organoselenium compounds with biological and/or pharmacological properties. regard, methods most commonly applied are alternative energy sources (microwave and ultrasound), reactions carried out under metal solvent-free conditions, catalytic processes, that involve sustainable solvents (ionic liquids, glycerol, PEG-400, ethanol water). The relevance synthesized is also highlighted....
Abstract A straightforward methodology for the synthesis of symmetrical thiosulfonates through direct oxidative coupling thiols is reported. Dibutyl diselenide was suitably applied as a catalyst selective conversion into respective in good yields. Moreover, mechanistic studies revealed radical reaction pathway preparation target products.
Abstract This study demonstrates a direct and regioselective selenylation protocol of unprotected uracils with diorganoyl diselenides using equivalent amount DMSO as oxidant minimum solvent, under catalysis by molecular iodine. methodology tolerates broad scope functional groups to provide several 5‐organoseleno‐substituted uracil derivatives in good excellent yields.
The addition of electrophilic selenium species to alkenes with the formation a seleniranium intermediate, that reacts nucleophiles, is one most useful method for new carbon-selenium bonds.1 Several reagents have been used purpose prepare or generate species, highlighting catalytic system I2/DMSO under solvent-free conditions.2 This was successfully employed alcoxy-chalcogenylation using non-chiral diselenides.3 Herein, we reported study about employment this in asymmetric alcoxi-selenyation...