A5047366093- Sulfur-Based Synthesis Techniques
- Radical Photochemical Reactions
- Catalytic C–H Functionalization Methods
- Organoselenium and organotellurium chemistry
- Chemical Synthesis and Reactions
- Innovative Microfluidic and Catalytic Techniques Innovation
- Synthesis of Indole Derivatives
- Oxidative Organic Chemistry Reactions
- Multicomponent Synthesis of Heterocycles
- Nanomaterials for catalytic reactions
- Catalytic Alkyne Reactions
- Synthetic Organic Chemistry Methods
- Synthesis and Characterization of Pyrroles
- Electrochemical Analysis and Applications
- Synthesis and Biological Evaluation
- Asymmetric Hydrogenation and Catalysis
- Synthesis of Organic Compounds
- Vanadium and Halogenation Chemistry
- Analytical Chemistry and Chromatography
- Fluorine in Organic Chemistry
- Electrocatalysts for Energy Conversion
- Microfluidic and Capillary Electrophoresis Applications
- Porphyrin and Phthalocyanine Chemistry
- Synthesis and Biological Activity
- Nanoplatforms for cancer theranostics
Universidade Federal de São Carlos
2022-2024
Cardiff University
2018-2023
Universidade Federal de Minas Gerais
2023
Universidade Federal de Santa Catarina
2014-2022
Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina
2020-2021
Universidade Federal de Santa Maria
2010-2019
Herein, we describe a solvent- and metal-free method for the synthesis of 3-chalcogenyl-indoles from indoles diorganyl dichalcogenides using an equivalent amount DMSO as oxidant, under catalysis by molecular iodine. This mild eco-friendly approach allowed preparation wide range 3-selenyl- 3-sulfenyl-indoles in good to excellent yields.
Herein, electrochemical annulations involving mediators and mediator-free conditions have been discussed. Also, the use of sacrificial electrodes has explored.
This feature article presents an overview of continuous flow chemistry, including photoflow and electroflow technologies in the preparation active pharmaceutical ingredients (APIs) fine chemical intermediates.
Anhydrous CeCl3 was successfully used as a catalyst for the synthesis of several 3-sulfenyl indoles in good to excellent yields through reaction indole with N-(alkylthio) and N-(arylthio)phthalimides DMF.
Abstract Electrochemistry is now regarded as one of the most efficient ways to synthesize highly functionalized moieties, such those difunctionalized vicinal alkene family, from simpler and more commercially available substrates. These transformations usually involve transition‐metal catalysts, hypervalent iodine reagents, or photocatalysts form new bonds often generate unwanted by‐products. Herein, we have outline examples electrochemical difunctionalization reactions that do not require a...
Abstract Achieving advances in the development of clean and efficient synthetic routes has become an important aim research. In recent years, search for new sustainable methodologies, notably environmentally benign procedures, gained attention scientific community. Electrosynthesis is a tool that been extensively studied due to its potential application chemical transformations it adheres principles green chemistry. Organochalogen compounds form class molecules, since many them have...
Herein, we report an eco-friendly, electrosynthetic approach for the intramolecular oxyselenylation of allyl-naphthol/phenol derivatives.
We outline examples of electrochemical alkyne functionalization reactions in connection with green and sustainable chemistry that proceed excellent atom economy.
In this review we target sp, sp<sup>2</sup>and sp<sup>3</sup>carbon fluorination, chlorination, bromination and iodination reactions using electrolysis as a redox medium. Mechanistic insights substrate reactivity are also discussed.
Herein, we report an electrochemical oxidative C(sp 2 )–H selenylation of activated arenes. The reaction proceeds in undivided cell at Pt‐electrodes the presence KI as supporting electrolyte, which could suffer oxidation anode. Using this benign, atom‐economic protocol, desired selenylated products were obtained regioselectively good to excellent yields by using a half molar equiv. diselenides.
We report an electrochemical oxidative intramolecular cyclization reaction between 2-alkynylphenol derivatives and different diselenides species to generate a wide variety of substituted-benzo[b]furans. Driven by the galvanostatic electrolysis assembled in undivided cell, it provided efficient transformation into oxidant-, base-, metal-free conditions open system at room temperature. With satisfactory functional group compatibility, products were obtained good excellent yields.
Electrosynthesis reactions have become an important field of study due to the increasing demand for sustainable and environmentally friendly chemical processes. Using a divided cell in electrosynthesis has shown promising results selectivity, efficiency, scalability. In this review, we discuss principles advantages using cells reactions, focusing on their application producing organic compounds. We also consider several factors that influence performance cells, such as choice electrode...
Abstract A facile and expedient iodocyclization of 4‐(2‐prop‐1‐ynylphenyl)‐1 H ‐pyrroles towards the synthesis polysubstituted 3 ‐benzo[ e ]indoles is reported. The transformation was optimized best results were obtained by using iodine (1.2 equiv,) in dichloromethane, potassium carbonate as base. starting 1,2,3,4‐tetrasubstituted pyrroles efficiently means a nickel(II) chloride‐promoted four‐component (nitromethane, amine, 2‐alkynylbenzaldehyde ethyl acetoacetate) reaction. Further...
This review presents significant and selected examples of organic synthesis methods that use visible-light-promoted photoarylation reactions without the need for additional photocatalysts.
Ce(OTf)3 was successfully employed as catalyst for the activation of hydroxyl group in Friedel–Crafts reaction aromatic compounds with propargylic alcohols nitromethane. The products were obtained good to excellent yields.
Anhydrous CeCl3 was successfully used as catalyst for the synthesis of several 3-propargyl indoles in good yields through reaction indole with propargyl alcohols nitromethane.
A novel and efficient SeCl2-mediated chalcogenative cyclization strategy toward 3-selenophen-3-yl-1H-indoles from readily available conveniently substituted propargyl indoles is described. It entails an unprecedented selenirenium-induced 1,2-indolyl shift prompted by the electrophilic addition of SeCl2 to triple bond indole, followed through intermediacy a 1-seleno-1,3-diene. The reaction takes place at room temperature shows excellent selectivity, broad substrate scope, wide functional...
Anhydrous CeCl3 was successfully employed as catalyst for the synthesis of (Z)-2-Arylsulfanyl allylic alcohols from propargylic and thiols under solvent free conditions. The products were obtained in good to excellent yields.