A5054114129- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Orthopedic Infections and Treatments
- Hip disorders and treatments
- Bone fractures and treatments
- Hip and Femur Fractures
- Pelvic and Acetabular Injuries
- Shoulder Injury and Treatment
- Knee injuries and reconstruction techniques
- Musculoskeletal synovial abnormalities and treatments
- Spine and Intervertebral Disc Pathology
- Sarcoma Diagnosis and Treatment
- Bone Tumor Diagnosis and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Shoulder and Clavicle Injuries
- Nerve Injury and Rehabilitation
- Meta-analysis and systematic reviews
- Bone and Joint Diseases
- Osteoarthritis Treatment and Mechanisms
- Sports injuries and prevention
- Trauma and Emergency Care Studies
- Lower Extremity Biomechanics and Pathologies
- Health Sciences Research and Education
- Medical Education and Admissions
- Cardiac tumors and thrombi
University of California, Los Angeles
2018-2025
Los Angeles Medical Center
2024
UCLA Medical Center
2022
Brown University
2022
Park University
2022
University of California System
2021
University of Washington
2014-2018
Northwest Hospital
2018
University of Washington Medical Center
2017
Seattle Public Library
2017
Postoperative blood product transfusions in elderly hip fracture patients cause concern for morbidity and mortality. The purpose of this study was to identify predictors short-term sequelae postoperative transfusion following geriatric surgery.We queried the American College Surgeons National Surgical Quality Improvement Program (ACS NSQIP) (⩾65 years) who sustained operative femoral neck, intertrochanteric, subtrochanteric fractures 2016. Multivariate regression used determine risk-adjusted...
This study investigated prognostic factors in nonmetastatic high-grade extremity osteosarcoma and the prognosis following resection of subsequent pulmonary metastases, with emphasis on effect chemotherapy-induced tumor necrosis.We reviewed 111 consecutive patients treated preoperative chemotherapy surgical resection, additional review 36 who had metastases resected.The overall 5-year survival rate was 53%. In resected primary tumors, tumor-free margin (P < .001) increasing necrosis (> 90%...
Determination of muscle viability during debridement is a subjective process with significant consequences. Evaluating color, consistency, contractility, and capacity to bleed (the 4 Cs) was established by study performed half century ago. This work reinvestigates the utility Cs using current histopathologic techniques.After institutional review board approval, 36 biopsies were prospectively collected at level-1 trauma center from 20 patients undergoing for open fracture (81%), compartment...
History Soft tissue injuries are an intrinsic component of any fracture. Treatment these soft is challenging, but integral element fracture care. The initial evaluation a patient with orthopaedic trauma must include detailed assessment the envelope. timing and method fixation directly influenced by degree to overlying tissues have been shown direct effect on postoperative function [5, 8, 13, 14, 17]. Various classification systems proposed help communicate, classify, guide treatment...
Much work has been done to develop tumor-targeting antibodies by selecting a phage antibody library on cancer cell lines. However, when tumor cells are removed from their natural environment, they may undergo genetic and epigenetic changes yielding different surface antigens than those seen in actual cases of cancer. We developed strategy that allows selection against situ both fresh frozen paraffin-embedded tissues using laser capture microdissection. By restricting binders internalizing...
The objective of this study was to explore race-based differences in 30-day complication rates following total joint arthroplasty (TJA) using a large national database.Patients undergoing primary, elective THA and TKA between 2012 2018 were retrospectively reviewed the ACS-NSQIP. We compared Black Hispanic patients with non-Hispanic White multivariate statistical models adjusting for demographic, operative, medical characteristics.A 324,795 200,023 TKA, respectively, identified. After THA,...
This investigation examined cemented femoral component use in total hip arthroplasty (THA) and its impact on the incidence of periprosthetic fractures (PPFx), a common failure mode THA. The study leverages data from American Joint Replacement Registry (AJRR) to assess trends usage over time, association with PPFx rates, compares survivorship 90-day complication rates between cementless THAs.
Summary: Posterior depression of the lateral articular surface tibial plateau can be difficult to elevate and support with morselized bone graft internal fixation. Progressive collapse after open reduction fixation has been described lead failure in treatment. A standard anterolateral approach tibia may not allow direct stabilization posterolateral joint given anatomic barriers fibular collateral ligament proximal tibiofibular articulation. Posterolateral approaches have depression. These...
Abstract This study investigated the comparative ability of bone marrow and skeletal muscle derived stromal cells (BMSCs SMSCs) to express a tenocyte phenotype, whether this expression could be augmented by growth differentiation factor‐5 (GDF‐5). Tissue harvest was performed on hind limbs seven dogs. Stromal were isolated via serial expansion in culture. After four passages, tenogenesis induced using either ascorbic acid alone or conjunction with GDF‐5. CD44, tenomodulin, collagen I, III...
This study investigates the results of closed manipulations performed under anesthesia (MUA) to evaluate whether it is an effective means treat posttraumatic knee arthrofibrosis.Retrospective review.Level I trauma center.Twenty-two patients with a mean age 40 underwent MUA for arthrofibrosis. Injuries included fractures femur, tibia, and patella as well ligamentous injuries traumatic arthrotomies. The time from treatment manipulation was 90 days. Mean follow-up after 7 months.Closed...
This study investigated whether the use of tranexamic acid (TXA) decreased blood loss and transfusion related cost following surface replacement arthroplasty (SRA).A retrospective review patients treated with TXA during a SRA, who did not receive autologous (TXA group) was performed. Two comparison groups were established; first group comprised donated their own pre-operatively (auto second donate (control). Outcomes included transfusions, post-operative haemoglobin (Hgb), complications,...