A5039778419- Renal cell carcinoma treatment
- Iron Metabolism and Disorders
- Drug Transport and Resistance Mechanisms
- Monoclonal and Polyclonal Antibodies Research
- Organ Donation and Transplantation
- Prostate Cancer Diagnosis and Treatment
- Mass Spectrometry Techniques and Applications
- Advanced Radiotherapy Techniques
- Prostate Cancer Treatment and Research
- Cancer Diagnosis and Treatment
- Ferroptosis and cancer prognosis
- Erythropoietin and Anemia Treatment
- Radiopharmaceutical Chemistry and Applications
- Protein Interaction Studies and Fluorescence Analysis
- Advanced Proteomics Techniques and Applications
- Cancer Genomics and Diagnostics
- Bladder and Urothelial Cancer Treatments
- Trace Elements in Health
- Multiple and Secondary Primary Cancers
- Renal and related cancers
Peoples' Friendship University of Russia
2022-2025
Introduction . Treatment of local RCC recurrence is a serious surgical and therapeutic problem. There no single standard strategy for the treatment locally recurrent RCC. Objective : to evaluate short- long-term results patients with recurrence. Material methods Among all participants (n=53), 48 had isolated (group 1), 5 synchronous metastases 2). All one or more foci underwent radical removal from may 2007 January 2024. In distant metastases, metastasectomy was performed. Results Laparotomy...
(1) Background: There are no reliable and widely available markers of functional iron deficiency (FID) in cancer. The aim the study was to evaluate role transferrin (Tf) as a marker cancer ovary (CrO) related FID. (2) Methods: groups consisted 118 patients with CrO 69 control females. Blood serum status determined on Beckman Coulter AU (USA) analyzer. Tf quantification performed by immunoturbidimetry. relative contents apo- holo-Tf (iron-free iron-saturated Tf, respectively) were eight...
The question of optimal times and indications for radiotherapy (adjuvant or salvage) after surgical treatment prostate cancer remains unanswered. Therefore, studies this problem are essential important clinical practice. article evaluates the effectiveness adjuvant compared to salvage in context recurrence-free survival associated adverse events. In 3 randomized trials meta-analysis, did not show improved radiotherapy. choice between should be based on individual patient history risk...
It is known that the saturation ratio of transferrin (Tf) with iron in human blood an important clinical parameter. Specific antibodies can be used to analyze subtle changes relative abundance different forms potentially associated a pathological process. Recently, authors this study were able obtain and characterize highly specific single-domain (nanobodies) predominantly recognize iron-saturated (holo-Tf) or iron-unsaturated (apo-Tf) form transferrin. In work, under conditions closer...
Risk factors for renal cell cancer (RCC) recurrence, including its local form, include stage and high Fuhrman grading system score, regional lymph node involvement, microvascular invasion, tumor necrosis, positive surgical margin, sarcomatoid or rhabdoid differentiation. Objective . The study analyzes data from Moscow Research Oncological Institute named by PA Herzen to determine the predictors of recurrence kidney based on surgically treated patients with recurrent RCC. Material methods We...
Background . Depending on the stage or location of tumor, kidney resection nephrectomy is gold standard treatment for renal cell carcinoma Preservation organ function essential patients with localized tumors, especially one kidney, chronic disease, proteinuria, multiple/bilateral masses. An important goal to preserve functional activity organ; however, surgery leads its decrease because loss vascularized nephrons and irreversible ischemic damage. Description clinical case A 24-year-old...
A number of single-domain antibodies (nanobodies) obtained previously to major marker blood proteins were tested as tools preprocess urine samples from patients with bladder cancer. Nanobody-based demonstrated unique possibilities for noninvasive diagnostic studies along other conventional methods, such electrophoresis and, in prospect, mass spectrometric analysis. testing 22 cancer showed that the development is accompanied by an increase contents proteins, including those known potential...