A5045443034- Malaria Research and Control
- Mosquito-borne diseases and control
- Global Maternal and Child Health
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- Drug-Induced Hepatotoxicity and Protection
- Vibrio bacteria research studies
- Liver Disease Diagnosis and Treatment
- Global trade and economics
- Asian Studies and History
- Primary Care and Health Outcomes
- Global Health Workforce Issues
- Healthcare Systems and Reforms
- Travel-related health issues
- Drug Transport and Resistance Mechanisms
- Health Systems, Economic Evaluations, Quality of Life
- SARS-CoV-2 and COVID-19 Research
University of Oxford
2021
Mahidol Oxford Tropical Medicine Research Unit
2014-2021
Mahidol University
2014-2021
Myanmar Oxford Clinical Research Unit
2017
Dexamethasone can reduce mortality in hospitalised COVID-19 patients needing oxygen and ventilation by 18% 36%, respectively. Here, we estimate the potential number of lives saved life years gained if this treatment were to be rolled out UK globally, as well cost-effectiveness implementing intervention. Assuming SARS-CoV-2 exposure levels 5% 15%, that, for UK, approximately 12,000 (4,250 - 27,000) could between July December 2020. that dexamethasone has a similar effect size settings where...
The number of Plasmodium falciparum malaria cases around the world has decreased substantially over last 15 years, but with spread resistance against anti-malarial drugs and insecticides, this decline may not continue. There is an urgent need to consider alternative, accelerated strategies eliminate in countries like Lao PDR, where there are a few remaining endemic areas. A deterministic compartmental modelling tool was used develop integrated strategy for P. elimination Savannakhet province...
Myanmar has the highest malaria incidence and attributed mortality in South East Asia with limited healthcare infrastructure to manage this burden. Establishing Community Health Worker (CHW) programmes is one possible strategy improve access diagnosis treatment, particularly remote areas. Despite considerable donor support for implementing CHW Myanmar, cost implications are not well understood. An ingredients based micro-costing approach was used develop a model of annual implementation CHWs...
Funding for malaria control and elimination in Myanmar has increased markedly recent years. While there are various tools currently available, two interventions receive the majority of funding Myanmar: (1) insecticide-treated bed nets (2) early diagnosis treatment through community health workers. This study aims to provide practical recommendations on how maximize impact from investment these interventions. A simple decision tree is used model intervention costs effects terms years life...
Healthcare services are often provided to a country as whole, though in many cases the available resources can be more effectively targeted specific geographically defined populations. In case of malaria, risk is highly heterogeneous, and interventions, such insecticide-treated bed nets malaria community health workers, populations way that maximises impact for available. This paper describes framework budget allocation based on principles cost-effectiveness analysis applied priority setting...
<ns4:p><ns4:bold>Background: </ns4:bold>The Asia-Pacific region has made significant progress against malaria, reducing cases and deaths by over 50% between 2010 2015. These gains have been facilitated in part, strong political financial commitment of governments donors. However, funding gaps persistent health system challenges threaten further progress. Achieving the regional goal malaria elimination 2030 will require an intensification efforts a plan for sustainable financing. This article...
<ns4:p><ns4:bold>Background: </ns4:bold>The Asia-Pacific region has made significant progress against malaria, reducing cases and deaths by over 50% between 2010 2015. These gains have been facilitated in part, strong political financial commitment of governments donors. However, funding gaps persistent health system challenges threaten further progress. Achieving the regional goal malaria elimination 2030 will require an intensification efforts a plan for sustainable financing. This article...
Despite demonstrated benefits and World Health Organization (WHO) endorsement, parenteral artesunate is the recommended treatment for patients with severe Plasmodium falciparum malaria in only one fifth of endemic countries. One possible reason this slow uptake that a course costlier than quinine might, therefore, pose substantial economic burden to health care systems. This analysis presents detailed account resources used treating by either or hospital on Thai-Myanmar border. The data from...
Community health volunteers (CHVs) are being used within a growing number of healthcare interventions, and they have become cornerstone for the delivery mass drug administration many neglected tropical disease control programs. However, greater understanding methods to value unpaid time CHVs contribute programs is needed. We outline two main approaches CHVs' (the opportunity cost replacement approaches). found that estimates economic costs relating can be significant, with averages different...
Abstract Background Mass drug administration (MDA) has received growing interest to accelerate the elimination of multi-drug resistant malaria in Greater Mekong Subregion. Targeted MDA, sometimes referred as focal is practice delivering MDA high incidence subpopulations only, rather than entire population. The potential effectiveness targeted was demonstrated a recent intervention Kayin State, Myanmar. Policymakers and funders need know what resources are required if or otherwise, be...
A Correction to this paper has been published: https://doi.org/10.1038/s41467-021-22038-x.
Abstract Background Mass drug administration (MDA) has received growing interest to accelerate the elimination of multi-drug resistant malaria in Greater Mekong Subregion. The potential effectiveness delivering targeted MDA was demonstrated a recent intervention Kayin State, Myanmar. Policymakers and funders need know what resources are required if is be included packages beyond existing interventions. Methods We used financial data from initiative, conducted estimate programmatic costs...