Christopher Fitzpatrick

ORCID: 0000-0002-3067-8328
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Parasites and Host Interactions
  • Tuberculosis Research and Epidemiology
  • Global Maternal and Child Health
  • Parasitic Diseases Research and Treatment
  • Virology and Viral Diseases
  • Animal Disease Management and Epidemiology
  • Diagnosis and treatment of tuberculosis
  • Syphilis Diagnosis and Treatment
  • Mosquito-borne diseases and control
  • Healthcare Systems and Reforms
  • Health Systems, Economic Evaluations, Quality of Life
  • Parasite Biology and Host Interactions
  • Global Public Health Policies and Epidemiology
  • Mycobacterium research and diagnosis
  • Primary Care and Health Outcomes
  • Breastfeeding Practices and Influences
  • Zoonotic diseases and public health
  • Complement system in diseases
  • Healthcare Policy and Management
  • Helminth infection and control
  • Malaria Research and Control
  • Pneumonia and Respiratory Infections
  • Reproductive tract infections research
  • Airway Management and Intubation Techniques
  • Research on Leishmaniasis Studies

World Health Organization
2008-2020

London School of Hygiene & Tropical Medicine
2016

Hospital for Tropical Diseases
2016

World Health Organization - Pakistan
2011-2014

University of Hargeisa
2013

World Health Organization - Egypt
2013

Alexandria University
2013

Coombe Women & Infants University Hospital
2011

Health Research Board
1995

National Maternity Hospital
1987-1991

The production of guidelines for the management drug-resistant tuberculosis (TB) fits mandate World Health Organization (WHO) to support countries in reinforcement patient care. WHO commissioned external reviews summarise evidence on priority questions regarding case-finding, treatment regimens multidrug-resistant TB (MDR-TB), monitoring response MDR-TB treatment, and models A multidisciplinary expert panel used Grading Recommendations Assessment, Development Evaluation (GRADE) approach...

10.1183/09031936.00073611 article EN European Respiratory Journal 2011-08-02

Neglected tropical diseases (NTDs) are communicable that occur under conditions of poverty and concentrated almost exclusively in impoverished populations the developing world. NTDs affect more than 1000 million people subtropical countries, costing economies billions dollars every year. Effective control can be achieved with use large-scale delivery single-dose preventive chemotherapy (PC) or intensified disease management (IDM) both, as is case for some such lymphatic filariasis, trachoma,...

10.1371/journal.pntd.0005136 article EN cc-by PLoS neglected tropical diseases 2017-01-19

Dengue is a rapidly emerging vector-borne Neglected Tropical Disease, with 30-fold increase in the number of cases reported since 1960. The economic cost illness measured billions dollars annually. Environmental change and unplanned urbanization are conspiring to raise health even further beyond reach systems households. health-sector response has depended large part on control Aedes aegypti Ae. albopictus (mosquito) vectors. cost-effectiveness first-ever dengue vaccine remains be evaluated...

10.1371/journal.pntd.0005785 article EN cc-by PLoS neglected tropical diseases 2017-08-14

Policy makers require information on costs related to inpatient and outpatient health services inform resource allocation decisions.Country data sets were gathered in 2008-2010 through literature reviews, website searches a public call for cost data. Multivariate regression analysis was used explore the determinants of variability unit using from 30 countries. Two models designed, with drawing upon 3407 9028 observations respectively. Cost estimates are produced at country regional level,...

10.1186/s12962-018-0095-x article EN cc-by Cost Effectiveness and Resource Allocation 2018-03-13

The Sustainable Development Goals (SDGs) have emerged as a global pledge to 'leave no one behind'. Under SDG 3, 'Ensure healthy lives and promote wellbeing for all', target 3.3 extends the Millennium (MDGs) beyond HIV, TB malaria 'end epidemic' of neglected tropical diseases (NTDs) by 2030. Other targets are also relevant NTDs, especially 3.8 (Universal Health Coverage), 6.1 (water) 6.2 (sanitation). This commentary summarises proposed NTD indicator (3.3) tracers (3.8 6.1/6.2). These will...

10.1093/inthealth/ihw002 article EN cc-by International Health 2016-03-01

Xpert MTB/RIF is a rapid test to diagnose tuberculosis (TB) and rifampicin-resistant TB. Cost affordability will influence its uptake. We assessed the cost, globally in 36 high-burden countries, of two strategies for diagnosing TB multidrug-resistant (MDR)-TB: with follow-on diagnostics, conventional diagnostics. Costs were compared funding available care control, donor investments HIV prevention care. Using MDR-TB would cost US$70-90 million per year be lower than diagnostics all countries....

10.1183/09031936.00147912 article EN cc-by-nc European Respiratory Journal 2012-12-20

BackgroundProgress in tuberculosis control worldwide, including achievement of 2015 global targets, requires adequate financing sustained for many years. WHO began yearly monitoring funding 2002. We used data reported to analyse from governments and international donors (in real terms, constant 2011 US$) associated progress low-income middle-income countries between 2002 2011. then assessed needed how this could be mobilised.MethodsWe included that about had at least three observations When...

10.1016/s2214-109x(13)70032-9 article EN cc-by-nc-nd The Lancet Global Health 2013-07-24

Background Lymphatic filariasis (LF), onchocerciasis, schistosomiasis, soil-transmitted helminths (STH) and trachoma represent the five most prevalent neglected tropical diseases (NTDs). They can be controlled or eliminated by means of safe cost-effective interventions delivered through programs Mass Drug Administration (MDA)—also named Preventive Chemotherapy (PCT). The WHO defined targets for NTD control/elimination 2020, reinforced 2012 London Declaration, which, if achieved, would result...

10.1371/journal.pntd.0005289 article EN cc-by PLoS neglected tropical diseases 2017-01-19

Preventive chemotherapy (PC), the large-scale administration of anthelminthics, is recommended by World Health Organization (WHO) for control soil-transmitted helminthiasis (STH). Since 2010, donated anthelminthics STH have boosted implementation PC programmes in children, achieving global coverage more than 60% 2015. The WHO Global Estimates attribute an annual loss over 3.3 million disability-adjusted life-years (DALYs) to STH. aim this study estimate impact on child morbidity.We used data...

10.1093/trstmh/trx082 article EN Transactions of the Royal Society of Tropical Medicine and Hygiene 2017-10-01

In a nationwide survey in 2011, multidrug-resistant tuberculosis (MDR TB) was found 5.2% and 40.8% of patients with new previously treated TB, respectively. These levels drug resistance are among the highest ever documented Africa Middle East. This finding presents serious challenge for TB control Somalia.

10.3201/eid1903.121287 article EN cc-by Emerging infectious diseases 2013-02-01

Background The control or elimination of neglected tropical diseases (NTDs) has targets defined by the WHO for 2020, reinforced 2012 London Declaration. We estimated economic impact to individuals meeting these human African trypanosomiasis, leprosy, visceral leishmaniasis and Chagas disease, NTDs controlled eliminated innovative intensified disease management (IDM). Methods A systematic literature review identified information on productivity loss out-of-pocket payments (OPPs) related NTDs,...

10.1371/journal.pntd.0006250 article EN cc-by PLoS neglected tropical diseases 2018-03-13

It has been estimated that $154 million per year will be required during 2015-2020 to continue the Global Programme Eliminate Lymphatic Filariasis (GPELF). In light of this, it is important understand program's current value. Here, we evaluate cost-effectiveness and cost-benefit preventive chemotherapy was provided under GPELF between 2000 2014. addition, also investigate potential hydrocele surgery.Our economic evaluation based on previously published health impact estimates (between 2014)....

10.1093/cid/ciw835 article EN cc-by Clinical Infectious Diseases 2016-12-08

A disabling and disfiguring disease that "begins where the road ends", yaws is targeted by WHO for eradication year 2020. The global campaign not yet financed. To evaluate within context of post-2015 development agenda, we perform a somewhat allegorical cost-effectiveness analysis eradication, comparing it to counterfactual in which simply wait more roads (the end poverty).We use evidence from four pilot sites other mass treatment campaigns set benchmarks cost 12 known endemic countries. We...

10.1371/journal.pntd.0003165 article EN cc-by PLoS neglected tropical diseases 2014-09-25

In the year 2000, eight Millennium Development Goals (MDGs) were adopted by United Nations and its member states [1].Even though health aspects that mostly affect poor explicitly included in MDGs (goals 4, 5, 6), many stakeholders felt important conditions not adequately represented or unjustly omitted [1,2].Among anonymous "other diseases" mentioned MDG 6 was a cluster of diseases became known as neglected tropical (NTDs).Their omission call to arms for NTD stimulus join forces gain...

10.1371/journal.pntd.0005759 article EN cc-by PLoS neglected tropical diseases 2017-09-14

Yaws is targeted for eradication by 2020. The mainstay of the strategy mass treatment followed case finding. Modeling has been used to inform programmatic requirements other neglected tropical diseases and could provide insights into yaws eradication. We developed a model transmission varying coverage number rounds treatment. estimated cases arising from an index (basic reproduction [R0]) ranged 1.08 3.32. To have 80% probability achieving eradication, 8 with were required at low estimates...

10.3201/eid2301.160487 article EN cc-by Emerging infectious diseases 2016-11-30

A service coverage index has recently been proposed to monitor progress towards universal health (UHC), and baseline results for 2015 are available. However, evidence on equity in that is scarce. The did not consider services neglected tropical diseases (NTDs), a group of preventable defined by WHO member states the basis disproportionate burden they place their poorest, remotest, otherwise most marginalised communities. Because much-needed lens it could provide, NTD should be efforts UHC...

10.1016/s2214-109x(18)30307-3 article EN cc-by-nc-nd The Lancet Global Health 2018-07-25
Coming Soon ...