Background: In the last decade, regenerative therapies have become one of leading disease modifying options for treatment knee osteoarthritis (OA). Still, there is a lack trials with direct comparison different biological treatments. Our aim was to directly compare clinical outcomes injections Bone Marrow Aspirate Concentrate (BMAC), Platelet-rich Plasma (PRP), or Hyaluronic acid (HA) in OA treatment. Methods: Patients pain and KL grade II IV were randomized receive BMAC, PRP, HA injection...

Background This study aimed to compare the effects of different treatments on quality life in knee osteoarthritis patients. It focused three therapies: bone marrow aspirate concentrate (BMAC), platelet-rich plasma (PRP), and hyaluronic acid (HA).

Tick-borne encephalitis (TBE) is a zoonotic flaviviral infection that growing public health concern in European countries. The aims of this research were to detect and characterize tick-borne virus (TBEV) Ixodes ricinus ticks at presumed natural foci Serbia, determine seroprevalence TBEV IgG antibodies humans animals. A total 500 I. examined for the presence by real-time RT-PCR, conventional nested PCR sequencing. To seroprevalence, 267 human sera samples collected, as 200 from different...

Aim: The aim of this study was to assess whether BMI, severity knee osteoarthritis, age and gender have any influence on the final clinical results bone marrow aspirate concentrate injection. Method: A total 111 participants with painful osteoarthritis different characteristics concerning before mentioned factors underwent (BMAC) therapy were followed up for 1 year. Result: Significant pain functional improvement observed in all participant groups. Participants' BMI did not outcome, but...

Aim: To assess the efficacy of a bioregenerative scaffold derived from bone marrow aspirate, cancellous autograft, platelet-rich plasma and autologous fibrin in treating supracondylar femur nonunions. Methods & materials: Three patients with nonunions following multiple surgical failures underwent stabilization application novel scaffold. x-rays subjective scales were collected before surgery at 6, 12 24 months post-surgery. Results: All exhibited healing sufficient callus formation, as...

Aim: To explore the effect that location of needle placement has on efficacy and tolerability bone marrow aspirate concentrate injections during treatment knee osteoarthritis. Methods: Bone were administered to 111 patients via superolateral, anteromedial or anterolateral portals. Pain was assessed by visual analog scale before 3, 7, 14 21 days after intervention. Knee function Western Ontario McMaster Universities Osteoarthritis Index, Injury Outcome Score International Documentation...

Introduction. In the treatment of various orthopedic conditions, regenerativetherapies, including platelet rich plasma and autologous stem-cell therapy, have recently been advancing. Knee cartilage lesions are a debilitating disease resulting in fibrillation subsequent degradation which can also involve subchondral bone lead to development osteoarthritis. Bone marrow mesenchymal stem cells heterogeneous mixture involved formation regenerative repair, whereas other capacity play role as...

All changes in the knee that appear after anterior cruciate ligament (ACL) lesion lead to difficulties walking, running, jumping especially during sudden of line movement. This significantly impairs quality life these subjects and leads decrease physical activity. Knee injuries make 5% all most severe acute sport injuries. The aim study was determine strength thigh muscles persons with unilateral rupture ACL evaluate potential bilateral differences between healthy injured leg.This involved...

Introduction. An anterior cruciate ligament injury represents a significant epidemiological problem worldwide, especially due to involving young, sporty and active working-age population. This study has been conducted in order compare the quality of life patients who had isolated tear those suffered from an associated meniscal injury. Material Methods. included 185 undergone reconstruction at Department Orthopedic Surgery Traumatology Novi Sad January 1st, 2012 December 31st, 2012. The were...

Abstract Background: The aim of this investigation was to identify and compare changes in the quality life among patients with knee osteoarthritis treated injections bone marrow aspirate concentrate, platelet-rich plasma, hyaluronic acid. Methods: study employed a single-center prospective clinical trial three arms, data were collected through repeated measurements using self-reported SF-36 scale. To analyze data's nature, linear mixed models (LMMs) utilized determine which injection types...

Background and Objectives: Advanced lung cancer is usually manifested by endoluminal tumor propagation, resulting in central airway obstruction. The objective of this study to compare the high dose rate brachytherapy treatment outcomes non-small-cell (NSCLC) depending on planning pattern—two-dimension (2D) or three-dimension (3D) planning. Materials Methods: was retrospective two groups patients were compared it (a group 101 who underwent 2D planned high-dose-rate endobronchial (HDR-EBBT)...

Introduction: Open extruded fractures of the talus occur in 2% talar fractures. These are challenging for surgeons due to complications such as infection, nonunion, and arthritis. The most common treatment method is reimplantation osteosynthesis. Case report: A 19-year-old presented with an open fracture talus, classified Hawkins II, following a fall from height. Emergency surgery involved wound debridement, reimplantation, osteosynthesis modified external fixation dynamic ankle joint...

Introduction. Unstable pelvic ring injuries are among the most serious of skeletal system. As they often associated with young age and multiple organ difficult for management. Material Methods. This study included 26 unstable surgically treated at Department Orthopedic Surgery Traumatology from August 2008 until 2015. The average 22 males 4 female patients was 45.4 years. common mechanism injury a traffic accident (19), fall height (6), one patient buried under rubble. Out who were operated,...

Introduction. Nonunion of long bones may often be associated with significant function loss affected extremity, joint stiffness, and even extremity amputation or systemic manifestations in the case infection. The aim this report is to highlight possibilities Ilizarov apparatus treatment fracture nonunions both lower legs treated by different operative methods show that it not necessary remove osteosynthetic material (intramedullary nail) every when nonunion occurs achieve its recovery. Case...

Introduction. The advancement of patient safety culture within a health institution is the basic component reduction errors and improvement general quality healthcare. aim this study was to assess by means Hospital Survey on Patient Safety Culture in Serbian setting. Material Methods. survey conducted five institutions form cross section study, which included 1,435 care workers. Results. Nine dimensions have been selected out 37 items explorative factor analysis. total percentage positive...

Introduction. Lung cancer often gives metastases in the bone system, of which wrist accounts for 0.1% and bones are primarily affected only 17% cases. We presented a patient with delayed diagnosis rare localization isolated lung to carpal ended upper arm amputation. Case report. A 56-year-old, laborer, healthy, smoker, coughing decades occasional expectoration, hoarseness, during last 3 months felt pain his right wrist. He denied trauma. Physical examination led tendovaginitis hand. visited...

Introduction. Indications for the use of partial shoulder prosthesis are dislocated four-part fractures and multi-part fractures-dislocations, impressive humeral head (including involvement more than 40% articular surface) ?head splitting? humerus. The aim this study was to present results application at Department Orthopedic Surgery Traumatology, Clinical Center Vojvodina in Novi Sad identify risk groups among participants. Material Methods. study, which retrospective, included 22 patients...

Introduction. Osteoporosis is a metabolic skeletal disease characterized by bone mineral density reduction, which may lead to an increased risk of fractures. Obesity condition excessive body fat that causes or aggravates many public health problems. As it easy be measured, mass index widely used as the degree obesity. Material and Methods. The study included 1.372 female orthopedic patients between ages 30 79 years who visited Clinical Centre Vojvodina in Novi Sad have dual-energy x-ray...

Introduction. Rupture of lateral collateral ligament the knee is most often joined with other ruptures. Isolated rupture this rare and there are few papers about treatment options results. Here we reported a case isolated outcome. Case report. A patient, 22 years old male, injured his left while playing American football. While landing on outstretched leg, he felt sudden pain in knee. The patient could not continue competition. Initial orthopedic examination revealed opening further...

A chronic periprosthetic infection with attendant failure of the knee extensor mechanism is one most disastrous outcome following total arthroplasty and arthrodesis may be last possible option treatment exception lover limb amputated. The aim this study to represent results achieve arhrodesis in patients chronically septic arhroplasty. In our retrospective we reviewed clinical record 27 who were treated Ilizarov circular external fixator for condition. Male female ratio was 13:14. Main age...

Rheumatoid arthritis (RA) is a chronic, inflammatory autoimmune disorder of unknown etiology characterized by synovial hyperplasia and resulting joint destruction.Despite reduced needs for total arthroplasty in the treatment end-stage damage hip knee RA, many patients still require to restore function quality life.We present surgical young RA patient with bilateral at Clinic Orthopaedics Traumatology Clinical Center Niš.Male seropositive was implanted over period 4 years (2008 2011).At time...

Introduction. More than a quarter of total number posterior fixations thoracolumbar spine is unsuccessful. Material and methods. The aim to compare short long fixation injuries. During the period 2006 2015 we examined 99 patients at Department Orthopedic Surgery Traumatology Clinical Center Vojvodina. Short was performed in 63 cases 36 cases. All underwent clinical, radiographic neurological evaluation. Mean age group 47 (18-66) it 43 (17-70). follow-up time 4,5 years. Results. Implants were...