A5057579056- Parasites and Host Interactions
- Parasitic Infections and Diagnostics
- Malaria Research and Control
- Amoebic Infections and Treatments
- Cancer-related Molecular Pathways
- Travel-related health issues
- Parasite Biology and Host Interactions
- Mosquito-borne diseases and control
- Dermatological diseases and infestations
- Drug-Induced Hepatotoxicity and Protection
- Parasitic infections in humans and animals
- Vector-borne infectious diseases
- Research on Leishmaniasis Studies
- Paleopathology and ancient diseases
- Hibiscus Plant Research Studies
- Hepatitis Viruses Studies and Epidemiology
- Enterobacteriaceae and Cronobacter Research
- Retinoids in leukemia and cellular processes
- Viral-associated cancers and disorders
- Global Health Workforce Issues
- Computational Drug Discovery Methods
- Mollusks and Parasites Studies
- Kruppel-like factors research
- Drug Transport and Resistance Mechanisms
- Integrated Water Resources Management
United States Public Health Service
2025
Israel Ministry of Health
2011-2023
Hebrew University of Jerusalem
2013-2014
Charité - Universitätsmedizin Berlin
2004
Humboldt-Universität zu Berlin
2004
Institute of Medical Microbiology and Hygiene
2004
A returned traveller from Asia presented with prolonged fever, abdominal pain, and eosinophilia. Abdominal CT revealed hypodense lesions of the liver. Fascioliasis was clinically suspected. Serology triclabendazole are unavailable in Israel; therefore, empiric treatment nitazoxanide transfer to Denmark for definitive serodiagnosis necessary.
The predominant sand fly species collected inside houses in Kfar Adumim, an Israeli village the Judean Desert that is a focus of cutaneous leishmaniasis, was Phlebotomus papatasi, which also caught attempting to bite humans. sergenti, rarely seen houses, constituted caves near village. Leishmania isolates from Ph. sergenti and humans typed as tropica. Sand human produced similar small nodular lesions hamsters. Isolates excreted factor (EF) subserotypes A(9) or A(9)B(2), characteristic L....
Cryptosporidium is a parasite that causes watery diarrhea among both children and adults. However, because many physicians do not routinely ask for diagnostic test, cryptosporidiosis prevalence likely underestimated. The current study investigated the of admitted to hospital with gastrointestinal symptoms. Stool sample was collected from each child subjected routine microbiological culture. presence tested by three different methods: real-time PCR (RT-PCR), quick antigen, microscopic...
Abstract Background Artemisinin-based combination therapies (ACTs) are recommended as first-line treatment against uncomplicated Plasmodium falciparum infection. Mutations in the PfKelch13 (PF3D7_1343700) gene led to resistance artemisinin Southeast Asia. Pfcoronin (PF3D7_1251200) confer reduced susceptibility vitro an African strain, but their role clinical has not been established. Methods We conducted a retrospective observational study of Israeli travellers returning from sub-Saharan...
We report seven cases of false-positive Plasmodium falciparum histidine-rich protein 2 (PfHRP2) malaria assay results in patients with acute schistosomiasis caused by Schistosoma mekongi. PfHRP2 assays were negative travelers infected mansoni or haematobium (n = 13). Malaria was ruled out and rheumatoid factor all patients.
In human papillomavirus (HPV)-infected cells, the p53 tumor suppressor is tightly regulated by HPV-E6–E6AP complex, which promotes it for proteasomal degradation. We previously demonstrated that c-Abl tyrosine kinase protects from complex-mediated ubiquitination and degradation under stress conditions. However, underlying mechanism was not defined. this study, we explored possibility targets E6AP thereby p53. interacts with phosphorylates E6AP. determined E3 ligase activity of impaired in...
Travel-related schistosomiasis is usually associated with prolonged freshwater exposure. Until recently, Uganda's crater lakes were considered free due to their high-altitude location. We describe an outbreak of acute after a brief exposure (mean, 22 ± 9.5 minutes) lake.
Cryptosporidium is a protozoan parasite associated with gastrointestinal illness. In immune-compromised individuals, the infection may become life-threatening. Cryptosporidiosis mandatory-reported disease but little was known about its prevalence and morbidity in Israel. Currently, laboratory diagnosis based on microscopy or copro-antigen tests underreported. Molecular assays, which are more sensitive specific, now increasingly used for identification screening. Here, molecular epidemiology...
Little is known about Plasmodium malariae, a relatively rare cause of malaria in returned travelers. Recently, polymerase chain reaction (PCR) use for diagnosis has enhanced specificity P. malariae detection. The study objective was to describe the unique aspects and clinical course travelers.Malaria reportable disease Israel. All PCR-proven monoinfections Israeli travelers between January 2008 2017 were retrieved from Ministry Health Reference Parasitology Laboratory. Data regarding method...
We describe a patient with Strongyloides stercoralis hyperinfection associated Streptococcus pyogenes and streptococcal toxic shock syndrome. To the best of our knowledge this association has not been previously described. A 78 year-old Israeli man, who was born in Iraq but lived Israel for 66 years, presented multi-organ failure including acute kidney hepatic injury, coagulopathy, lactic acidosis. He had medical history aortic valve replacement, diabetes mellitus, spinal stenosis, low back...
A 65-year-old Israeli working in Welkait, Ethiopia, not using malaria prophylaxis, developed fever. Malaria rapid detection test was consistent with non-falciparum (plasmodium lactate dehydrogenase+/histidine-rich protein− [LDH+/HRP−]) but microscopy showed typical Plasmodium falciparum. HRP2/3 were negative by polymerase chain reaction. The patient suffered two recrudescence episodes following artemether–lumefantrine and atovaquone–proguanil treatments, responded to mefloquine treatment.
During 2002 to 2011, 275 of 6828 children with giardiasis in Israel were reported recurrent, over 6 months apart, episodes. The only significant multivariable-adjusted risk predictor a recurrent episode was non-Jewish ethnicity (hazard ratio, 4.61 [95% confidence interval, 3.32-6.40]; P < .001), also accompanied by interaction lower maternal education.
This is the first case report of human Capillaria philippinensis imported from Thailand and diagnosed in Israel by PCR biopsy material. Capillariasis can be fatal if untreated should suspected among returning travelers or foreign workers with protein-losing enteropathy long standing diarrhea.
Immigration from east Africa (mainly Eritrea) to Israel peaked during 2011–2013. Little is known about the prevalence of chronic parasitic diseases in this population. We performed a survey Schistosomiasis and Strongyloidiasis among immigrants, both are pararsites that can cause infections, lead significant morbidity complications. A prospective adults (>18 years) Eritrea was at primary care clinic for immigrants Tel Aviv, Israel. Participants provided written informed consent. Stool blood...
Toxocariasis is a rare and underdiagnosed disease, data concerning epidemiological aspects of toxocariasis in Israel are lacking. We describe the epidemiology Israel. Epidemiological all serology tests between 2005 2019 were retrieved compared with detailed demographics. Overall, 464 positive cases from total 10,896 conducted identified, reflecting mean positivity rate 4.4% (yearly range, 2-22%). Over years, significant increase yearly was noted, without parallel change rate. The greatest...