Zhengsheng Yang

ORCID: 0000-0001-6311-9939
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About
Contact & Profiles
Research Areas
  • Monoclonal and Polyclonal Antibodies Research
  • Alzheimer's disease research and treatments
  • Psoriasis: Treatment and Pathogenesis
  • S100 Proteins and Annexins
  • Synthesis and Characterization of Heterocyclic Compounds
  • Biochemical Acid Research Studies
  • RNA Research and Splicing
  • Eicosanoids and Hypertension Pharmacology
  • Advanced Glycation End Products research
  • Sports injuries and prevention
  • Nuclear Structure and Function
  • Cardiomyopathy and Myosin Studies
  • Solar-Powered Water Purification Methods
  • Sports Performance and Training
  • Neurological Disease Mechanisms and Treatments
  • Surface Modification and Superhydrophobicity
  • Amyotrophic Lateral Sclerosis Research
  • Neurogenetic and Muscular Disorders Research
  • Neurological diseases and metabolism
  • Sports Dynamics and Biomechanics
  • Rheumatoid Arthritis Research and Therapies
  • Retinoids in leukemia and cellular processes
  • Tryptophan and brain disorders
  • Solar Thermal and Photovoltaic Systems

Kunming University of Science and Technology
2023-2024

Hebei University of Technology
2024

Yunnan Yingmao Biotechnology (China)
2023

First Hospital of Qinhuangdao
2015-2021

Chinese Culture University
2021

To solve the clinical transformation dilemma of lamin A/C (LMNA)-mutated dilated cardiomyopathy (LMD), we developed an LMNA-mutated primate model based on similarity between phenotype primates and humans. We screened out patients with LMD compared data TTN-mutated mutation-free to obtain unique phenotype. After establishment LMNA c.357-2A>G model, were continuously observed for 48 months, echocardiographic, electrophysiological, histologic, transcriptional recorded. The was found highly...

10.1016/j.jacbts.2023.11.002 article EN cc-by-nc-nd JACC Basic to Translational Science 2024-01-24

Our previous research showed the antioxidant activity of anthocyanins extracted from Aronia melanocarpa black chokeberry in vitro. Ischemia acute kidney injury is a significant risk developing progressive and deterioration renal function leading to clinic chronic disease. There were many attempts protect against this progression damage. Current study was designed examine effect pretreatment with three named cyanidin-3-arabinoside, cyanidin-3-glucodise, cyaniding-3-galactoside...

10.1155/2021/7372893 article EN cc-by Mediators of Inflammation 2021-01-22

Poly(PR) is a dipeptide repeat protein comprising proline and arginine residues. It one of the translational product expanded G4C2 repeats in C9orf72 gene, its accumulation contributing to neuropathogenesis C9orf72-associated amyotrophic lateral sclerosis and/or frontotemporal dementia (C9-ALS/FTD). In this study, we demonstrate that poly(PR) alone sufficient induce neurodegeneration related ALS/FTD cynomolgus monkeys. By delivering via AAV, observed PR proteins were located within nucleus...

10.1016/j.nbd.2023.106197 article EN cc-by-nc-nd Neurobiology of Disease 2023-06-15

The purpose of this study was to explore the kinematical characteristics jumping discus throwing. Eight male right-handed throwers who used practice throwing technique were recruited as participants. Two high-speed digital cameras with 120 Hz sampling rate synchronized capture movement. captured images processed using a motion analysis suite, and markers attached joints on digitized manually. Based results, should keep smaller shoulder-hip twisting right anterior superior iliac spine...

10.3390/ijerph182413414 article EN International Journal of Environmental Research and Public Health 2021-12-20

Objective To estimate the influence of curcumin on psoriasis-like lesions and proliferating cell nuclear antigen(PCNA)expression in guinea pigs, so as to investigate therapeutic effect mechanism psoriasis. Methods A model skin inflammation was established by applying propranolol 5% cream(4 times a day for 3 weeks)to dorsal ears 30 pigs , which were then equally classified into 5 groups: group receiving no treatment, observation treatment but 2 weeks, control treated with intragastric...

10.3760/cma.j.issn.0412-4030.2015.03.008 article EN Chinese Journal of Dermatology 2015-03-15
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