A5086452241- Atherosclerosis and Cardiovascular Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Essential Oils and Antimicrobial Activity
- Plant-Microbe Interactions and Immunity
- Cholesterol and Lipid Metabolism
- Nematode management and characterization studies
- Cynara cardunculus studies
- Pomegranate: compositions and health benefits
- Computational Drug Discovery Methods
- Protein Structure and Dynamics
- RNA regulation and disease
- Plant Pathogens and Resistance
- Tea Polyphenols and Effects
- Immune cells in cancer
- Natural Antidiabetic Agents Studies
- Cancer, Lipids, and Metabolism
- Fatty Acid Research and Health
- Soybean genetics and cultivation
- Ethnobotanical and Medicinal Plants Studies
- Phytochemistry and biological activity of medicinal plants
- interferon and immune responses
- Food Science and Nutritional Studies
- Berberine and alkaloids research
- Nitrogen and Sulfur Effects on Brassica
- Plant Genetic and Mutation Studies
University of Tabuk
2020-2024
Namık Kemal University
2024
King Abdulaziz University
2021-2022
Bacillus genus exhibits antagonistic potential against a broad range of pathogenic fungi. This study presents the antifungal lipopeptides (LPs) produced by novel strain altitudinis TM22A to suppress infection Alternaria rot on tomato. We investigated effect ten species alternata, where four strains TM22A, MCM61, S2, and CPCF54 exhibited activity. The LPs extracted from restricted mycelial growth conidial germination A. alternata in vitro with highest inhibition TM22A. Liquid chromatography...
Atherosclerosis is potentially correlated with several cardiac disorders that are greatly associated cellular oxidative stress generation, inflammation, endothelial cells dysfunction, and many cardiovascular complications. Berberine a natural isoquinoline alkaloid compound widely modulates pathogenesis of atherosclerosis through its different curative potentials. This in silico screening study was designed to confirm the potent restorative properties berberine chloride as...
Aloe barbadensis is a stemless plant with length of 60-100 cm juicy leaves which used for its remedial and healing properties in different suburbs various countries. The present study was conducted to investigate the effect A. leaf extract (aqueous ethanolic) yeast induced pyrexia acetic acid writhing rat model evaluate antipyretic biomarkers phytochemical screening computational analysis. For analgesic activity 60 Albino rats (160-200 kg) were divided into four groups. Of 4 groups, control...
Targeting foam cells reduces the risk and pathophysiology of atherosclerosis, which they are one its early hallmarks. The precise mechanism action fucoidan, a potential anti-atherogenic drug, is still unknown. Our objective was to assess ability fucoidan regulate expression ATP-binding cassette transporter A1 (ABCA1) in ox-LDL-induced THP-1 macrophages. Molecular docking used predict how interacts with anti-foam cell markers, further vitro experiments were performed evaluate protective...
Background: Atherosclerosis (AS), a major risk factor for stroke and brain tissue destruction, is an inflammatory disease of the blood vessels, underlying pathology inflammation mediated by various chemokines cytokines. Quercetin, natural flavonol, reported to have both anti-inflammatory antioxidant properties. As such, in present study, we evaluated antiatherogenic effects quercetin human THP-1 cell line vitro also signaling mechanisms using silico analysis. Materials Methods: macrophages...
Atherosclerosis may lead to cardiovascular diseases (CVD), which are the primary cause of death globally. In addition conventional therapeutics for CVD, use nutraceuticals that prevents cholesterol deposition, reduce existing plaques and hence anti-atherosclerotic effects appeared be promising. As such, in present study we evaluated beneficial punicalagin, a phytochemical against an atherosclerotic cell model vitro. Cytotoxicity assays were examined 10 µM concentration punicalagin on THP-1...
In the present study, chemical composition and total phenolic (TPC) flavonoid contents (TFC) of eight soybean cultivars (Giza 21, Giza 22, 35, 111, 82, 83, Crawford, Holliday) were estimated. Moreover, antioxidant activity in vitro cytotoxic activities against HepG-2 MCF-7 evaluated. Crawford recorded higher than 40% crude protein. The analysis revealed that TPC values seed extracts ranged from 10.5 mg GAE/g extract 35 to 6.4 22. TFC varied 1.20 QE/g 111 0.55 Crawford. exhibited highest...
The complexity, diagnosing challenges, and lack of recognized therapies for non-alcoholic fatty liver disease have made it a major problem. It is anticipated that (NAFLD) will surpass hepatitis C as the most prevalent chronic in adults children over next ten years. also to emerge primary reason transplantation. coexists with obesity, hypertension, type 2 diabetes mellitus, dyslipidemia. Current clinical trials concentrated on number reasons, how these treatments fit into current paradigm...
Atherosclerosis is a chronic inflammation characterized by macrophage infiltration, lipid deposition, and arterial wall thickening. Prevention of atherosclerosis nutraceuticals gaining attention. Myricetin, dietary flavonol, claimed to possess anti-atherosclerosis properties. We studied myricetin’s effect on the atherosclerosis-associated molecular mechanism. Cytotoxicity proliferation testing check viability myricetin-treated THP-1 macrophages monocyte migration study in presence absence...
Aims: To assess the anti-atherosclerotic effects of Myricetin (pharmaceutical) in human THP-1 macrophages following IFN-γ or MCP-1 stimulation.
 Study Design: The protective myricetin against atherosclerosis was evaluated using humanTHP-1 and studying parameters namely, cell viability, proliferation, migration, inflammation related gene expression cholesterol efflux vitro.
 Place Duration Study: line: Department biochemistry (faculty science), Cell Culture Unit, Experimental...
Atherosclerosis is a widespread and chronic progressive arterial disease that has been regarded as one of the major causes death worldwide. It caused by deposition cholesterol, fats, other substances in tunica intima which leads to narrowing blood vessels, loss elasticity, wall thickening, thus causing difficulty flow. For long time, most crucial approaches treatment prevention cardiovascular illnesses use natural products. Numerous studies on chemicals are beneficial against atherosclerosis...
The extensive networks of molecular and functional alterations that take place at many levels biological structure are studied using traditional toxicology quantitative research. As society places more emphasis on the potential health concerns connected with exposure to chemicals encountered in daily life, it is imperative accurate predictive risk-assessment tools be developed. development such strategies necessitates a comprehensive understanding mechanisms by which xenobiotic injure impair...
Oilseed rape (Brassica napus L.) is an important oilseed crop. We examined the diversity of germplasm expressed at three distinct levels (i.e., morphological, biochemical, and DNA levels). In this study, 150 B. L. accessions with check varieties were provided by Bioresources Conservation Institute. The was grown in field conditions for data collection 15 quantitative nine qualitative agro-morphological traits. result indicated that traits, highest coefficient variation recorded plant height...
Several harmful biochemical changes in plasma and blood are attributed to cigarette smoking, these alterations the target of treatment efforts. The current research looked at how regularly drinking green tea affects hard-core smokers. 120 healthy male volunteers was divided into four groups: nonsmokers, smokers, nonsmokers who also drank tea, smokers tea. In addition measuring glucose, HbA1c, hemoglobin, hematocrit, total cholesterol, lipoprotein patterns (HDL, LDL, VLDL), lipid...
Osteoporosis is systematic skeleton disease that defined by low bone mass and changes in structure of tissue, which leads to high risks weak bones fractures. According International Foundation 1 3 women 5 men over the age 50 years are suffering from osteoporosis. Barley grass powder best functional food for supplying nutrients removing toxins human cells, its components have also provided significant health benefits because it contains many such as essential amino acids, fiber, vitamins both...