Transcatheter aortic valve implantation is recommended in advanced stenosis, elderly patients who are not suitable for surgery. Valve embolization one of the most important complications that life-threatening. A 61-year-old male patient was being followed up with a complaint shortness breath. He had history coronary artery bypass graft operation. Transthoracic echocardiography revealed severe stenosis. Transfemoral transcatheter performed, but while balloon passed through valve, embolized...

The aim of the present study is to evaluate whether blood count parameters differ according stages Fontaine's classification and investigate relationship between hemogram severity disease.Eighty-two peripheral arterial disease patients were examined prospectively. Patients classified Fontaine system. Fifty newly diagnosed included in study. neutrophil-to-lymphocyte ratio, mean platelet volume, red cell distribution width values recorded.Mean ratio found be 3.31 ± 1.1% Stage I, 3.11 1.3% II,...

Ventricular shunts are used to drain cerebrospinal fluid into extra-cranial spaces. Ventriculoatrial (VA) provided transfer from the cerebral ventricle right atrium of heart. A single center experience indications, procedure, and clinical outcomes in VA shunt was presented current study.VA were applied 10 patients who had repeated previous dysfunction or infection. The reasons, findings, replacement methods, postoperative follow-ups recorded retrospectively.There seven female (70%) three...

Objective: The aim of this study was to determine the relationship between oxidative stress markers and duration ischemia in rat mesenteric peripheral models. Methods: Forty rats were divided into five equal groups, as follows: Group I (control group) sacrificed baseline characteristics serum markers; superior artery clamped via a simple laparotomy induce Groups II III; right common femoral IV V. Blood samples taken at 2 (Groups IV) 6 III V) hours after these procedures. total status (TOS),...

Ischemia reperfusion injuries can be threatening to end organ viability and progress, with mortal morbid outcomes. In particular, neural tissues are highly sensitive hypoxia stress. This study aimed determine the neuroprotective effects of rosuvastatin on spinal cord ischemia injury. Forty male Sprague- Dawley rats were divided into four equal groups: group I (control), II (sham simple laparotomy), III (ischemia-reperfusion), IV (ischemia-reperfusion continuous utilization), V...

Abstract The aim of this study was to investigate whether anticoagulant and antiaggregant agents have protective effects against oxidative damage induced by peripheral ischemia–reperfusion (I/R). Groups were created as follows: control group, I/R group (sham group), plus acetylsalicylic acid (Group I), I/R+clopidogrel II), I/R+rivaroxaban III), I/R+bemiparin sodium IV), I/R+enoxaparin V). In I, II, III, IV, V, drugs administered daily for 1 week before creation. Peripheral in the groups...

Antithrombotic agents play important roles in the prophylactic and therapeutic management of many cardiovascular disorders. Therefore, researchers have focused on developing new strategies for anticoagulation. New oral anticoagulants factor Xa inhibitors are products such research. Although they identified as advantageous, there limited data available about their multisystemic interactions. Thus, antiangiogenic behaviors low molecular weight heparins (LMWHs) were investigated this study. The...

Objective: Myocardial ischemia severely reduces myocyte longevity and function. Extensive interstitial edema cell damage occur as a result of myocardial reperfusion injury. Current therapies are directed at prevention ischemia-induced to cardiac tissue. Iloprost is novel pharmaceutical agent for the treatment ischemia. Methods: Twenty rats were segregated into four experimental groups. The procedure control group consisted undergoing sham operation. remaining 16 divided two equal first...

Objective: To investigate the predictive value of serum nitrate (nitrogen oxide: NOx) levels in detection peripheral and mesenteric ischaemia durations.Methods: Rats were sacrificed for determining basal values NOx Group I without any intervention. The superior artery was clamped Groups II III blood samples taken at 120 minutes 360 III. right common femoral IV V V.Results: peak obtained IV. reduced advanced periods ischaemia. In other words, significantly higher two hours (p < 0.05), to...

Lithium overdose can be associated with cardiac toxicity, especially in those underlying heart disease. Toxic levels of serum lithium are cardiotoxic effects ranging from simple ECG disorders to dysrhythmias, cardiomyopathy and even acute myocardial infarction (AMI). This report describes a patient AMI accompanied by high blood lithium.A 62-year-old woman was admitted the emergency department due weakness chest pain. Her revealed ST elevation leads DI, aVL V5-6, ventricular rate 80 bpm....

Background:Calcium dobesilate (CaD) is a member of the synthetic veno-active drug family. Only small number reports are available that describe micro-angiogenic effects CaD in current literature. Material and Methods:The antiangiogenic potential was compared with bevacizumab (Bb), which potent angiogenesis inhibitor, chick chorioallantoic membrane model. Four different concentrations (10–7, 10–6, 10–5, 10–4 M) pellet were prepared for each drug. Changes vessel formation scored according to...

Acute mesenteric ischaemia is an emergency condition that requires urgent and expeditious diagnosis immediate surgical or medical intervention. The initial hours are critical for the recovery of affected bowel segment. Thus, its clinic diagnostic biomarkers important when it comes to reducing mortality morbidity rates.Twenty-four male Sprague-Dawley rats were included in study. divided into three equal groups. Those Group I sacrificed determine basal serum values ischaemia-modified albumin...

The susceptibility of tissue to ischemia-reperfusion (I/R) injury is a major obstacle regeneration and cellular survival. In this study, we investigated the possible renoprotective effect dabigatran in an experimental renal I/R model.A total 25 rats were randomly divided into 5 equal groups. control group was used obtain basal values oxidant antioxidant biomarkers. sham prolidase malondialdehyde (MDA) levels after ischemia (for 45 minutes) reperfusion 1 hour). A standard diet followed. Oral...

Chronic venous insufficiency may cause stasis ulcers that significantly impact on the quality of life. Many methods have been described for preventing or treating these ulcers. However, often recur as a result continuing insufficiency. Here we report 30-year-old male patient with chronic He was admitted to hospital owing recurrent had history various flavonoid drug usage and compression therapies over previous six years. Venous Doppler sonography revealed combined saphenofemoral deep femoral...

Thromboangiitis obliterans (TAO) affects small- and medium-sized vessels of the extremities via a non-atherosclerotic inflammatory process in elderly. Although diagnostic criteria have been determined, only few studies described laboratory features. Diagnostic biomarkers are important for reducing disruptions caused by TAO. The importance mean platelet volume (MPV) was investigated TAO patients. Forty-four patients diagnosed with (study group) 45 healthy individuals (control were included...

Objective: Ginseng is a traditional herbal medicinal product widely used for various types of diseases because its cellular protective effects.Possible effects ginseng were investigated in blood, cardiac and renal tissue samples compared with common anti-aggregant agents an animal ischaemia-reperfusion (I/R) model.Methods: Twenty rats equally divided into four different groups as follows: control group (I/R-induced without drug use), I (acetylsalicylic acid-administered group), II...

Cardiac resynchronisation therapy has been shown to be an effective treatment improve functional status and prolong survival of patients in advanced chronic heart failure. This study assessed the surgical outcomes left anterior mini-thoracotomy for implantation ventricular epicardial pacing leads cardiac therapy.Our consisted 30 consecutive who underwent with a thoracotomy between November 2010 April 2012 our clinic. Postoperative follow up included assessment New York Heart Association...

Aim: This study aims to examine the distribution of major complications in patients undergoing carotid endarterectomy (CEA) based on gender. The primary objective is assess potential effects gender perioperative events hospital. Material and Methods: At Başakşehir Çam Sakura City Hospital, aged 18 over who underwent CEA between September 2020 November 2023, were retrospectively analyzed. categorized into two groups their Patient characteristics obtained from electronic medical records....

Aims: Infective endocarditis (IE) is a severe cardiac pathology associated with high morbidity and mortality. Early identification of disease severity mortality risk using simple, rapid, cost-effective tests can significantly improve clinical outcomes. This study aims to provide clinicians valuable information on the prognostic importance SIII NLR in management IE patients guide potentially more effective perioperative interventions. Methods: retrospectively investigates relationship between...

Objective: This study aimed to provide clinicians with valuable information on the prognostic importance of renal function tests in management infective endocarditis (IE) patients and guide potentially more effective perioperative interventions. Methods: In this study, relationship between mortality who underwent surgical treatment for IE March 2020 November 2023 was retrospectively examined. A total 100 over age 18 were included study. Results: Patients experienced had significantly higher...

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Giriş: Mediyastinit kalp cerrahisinde yıkıcı bir komplikasyondur. En sık tedavi şekli debridman sonrası yaranın tekrar kapatılması ve mediyastenin antibiyotikle irrigasyonudur. Vakum yardımlı kapalı yöntemi son zamanlarda ortaya çıkmış tekniği olup, sternotomi mediyastinitler gibi zor yaralarda iyileşmeyi kolaylaştırmaktadır. Hastalar Yöntem: Ocak 2006-Ocak 2010 tarihleri arasında derin sternal yara gelişen 41 hasta kullanılan yöntemine göre iki gruba ayrıldı. Mediyastinitli 22 devamlı vakum...

Objective. Demonstration of the advantages using natural Y shaped form saphenous vein graft, which is most preferred coronary bypass graft after internal thoracic artery (ITA). Methods. 32 patients with disease who underwent grafting (CABG) 3 or more distal anastomoses between January 2014 and 2018 were included in study. The grafts used these operations beside LİMA-LAD anastomosis. Patients have been evaluated terms early short-term survival, cardiac events, need for reoperation,...