A5036934096- Cardiac Ischemia and Reperfusion
- Vascular Procedures and Complications
- Central Venous Catheters and Hemodialysis
- Peripheral Artery Disease Management
- Cardiac Structural Anomalies and Repair
- Cerebrovascular and Carotid Artery Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Venous Thromboembolism Diagnosis and Management
- Paraoxonase enzyme and polymorphisms
- Cardiac Imaging and Diagnostics
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Abdominal vascular conditions and treatments
- Muscle and Compartmental Disorders
- Aortic Disease and Treatment Approaches
- Cardiac and Coronary Surgery Techniques
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac Valve Diseases and Treatments
- Vasculitis and related conditions
- Acute Kidney Injury Research
- Heparin-Induced Thrombocytopenia and Thrombosis
- Vascular anomalies and interventions
- Case Reports on Hematomas
- Dialysis and Renal Disease Management
- Aortic aneurysm repair treatments
- Angiogenesis and VEGF in Cancer
Trakya University
2013-2024
Dicle University
2012-2015
Namık Kemal University
2013
The aim of the present study is to evaluate whether blood count parameters differ according stages Fontaine's classification and investigate relationship between hemogram severity disease.Eighty-two peripheral arterial disease patients were examined prospectively. Patients classified Fontaine system. Fifty newly diagnosed included in study. neutrophil-to-lymphocyte ratio, mean platelet volume, red cell distribution width values recorded.Mean ratio found be 3.31 ± 1.1% Stage I, 3.11 1.3% II,...
Ventricular shunts are used to drain cerebrospinal fluid into extra-cranial spaces. Ventriculoatrial (VA) provided transfer from the cerebral ventricle right atrium of heart. A single center experience indications, procedure, and clinical outcomes in VA shunt was presented current study.VA were applied 10 patients who had repeated previous dysfunction or infection. The reasons, findings, replacement methods, postoperative follow-ups recorded retrospectively.There seven female (70%) three...
Buerger's disease (BD) remains a debilitating condition and early diagnosis is paramount for its effective management. Despite many published diagnostic criteria BD, selective have been utilized in different vascular centers to manage patients with BD worldwide. A recent international Delphi Consensus Study on the of showed that none these universally accepted as gold standard. Apart from presence smoking, distinct differences between them, rendering direct comparison patient outcomes...
Objective: The aim of this study was to determine the relationship between oxidative stress markers and duration ischemia in rat mesenteric peripheral models. Methods: Forty rats were divided into five equal groups, as follows: Group I (control group) sacrificed baseline characteristics serum markers; superior artery clamped via a simple laparotomy induce Groups II III; right common femoral IV V. Blood samples taken at 2 (Groups IV) 6 III V) hours after these procedures. total status (TOS),...
Ischemia reperfusion injuries can be threatening to end organ viability and progress, with mortal morbid outcomes. In particular, neural tissues are highly sensitive hypoxia stress. This study aimed determine the neuroprotective effects of rosuvastatin on spinal cord ischemia injury. Forty male Sprague- Dawley rats were divided into four equal groups: group I (control), II (sham simple laparotomy), III (ischemia-reperfusion), IV (ischemia-reperfusion continuous utilization), V...
Abstract The aim of this study was to investigate whether anticoagulant and antiaggregant agents have protective effects against oxidative damage induced by peripheral ischemia–reperfusion (I/R). Groups were created as follows: control group, I/R group (sham group), plus acetylsalicylic acid (Group I), I/R+clopidogrel II), I/R+rivaroxaban III), I/R+bemiparin sodium IV), I/R+enoxaparin V). In I, II, III, IV, V, drugs administered daily for 1 week before creation. Peripheral in the groups...
Objective: Ischemia-reperfusion injury after acute ischemia treatment is a serious condition with high mortality and morbidity.Ischemia-reperfusion may result in organ failure particularly kidney, lung, liver, heart.In our study, we investigated the effects of papaverine vitamin C on ischemia-reperfusion developed rat liver occlusion-reperfusion aorta.Methods: 32 Sprague-Dawley female rats were randomized into four groups (n=8).Ischemia was induced infrarenal aortic cross-clamping for 60...
Ischemia/reperfusion injury is one of the most challenging postoperative situations in vascular surgery, both elective procedures with prolonged clamping time and delayed emergency cases occlusion. The inflammatory response that develops during ischemia oxygen-free radicals proliferate reperfusion have detrimental effects on brain, heart, kidneys. In this study, we aimed to compare vanillic rosmarinic acid preventing ischemia/reperfusion a lower limb ischemia-reperfusion model rats.
Antithrombotic agents play important roles in the prophylactic and therapeutic management of many cardiovascular disorders. Therefore, researchers have focused on developing new strategies for anticoagulation. New oral anticoagulants factor Xa inhibitors are products such research. Although they identified as advantageous, there limited data available about their multisystemic interactions. Thus, antiangiogenic behaviors low molecular weight heparins (LMWHs) were investigated this study. The...
Objective: Myocardial ischemia severely reduces myocyte longevity and function. Extensive interstitial edema cell damage occur as a result of myocardial reperfusion injury. Current therapies are directed at prevention ischemia-induced to cardiac tissue. Iloprost is novel pharmaceutical agent for the treatment ischemia. Methods: Twenty rats were segregated into four experimental groups. The procedure control group consisted undergoing sham operation. remaining 16 divided two equal first...
Takayasu’s arteritis (TA) is a chronic inflammatory granulomatous vasculitis which affects large and medium arterial vessels. The disease involves especially subclavian arteries aortic branches but it can consist of any arteries. major pathology panarteritis with intima proliferation defects the elastic lamina We present case central retinal artery occlusion in TA as first presentation disease. To best our knowledge, that demonstrates an initial manifestation TA. A 48-year-old woman was...
Objective: To investigate the predictive value of serum nitrate (nitrogen oxide: NOx) levels in detection peripheral and mesenteric ischaemia durations.Methods: Rats were sacrificed for determining basal values NOx Group I without any intervention. The superior artery was clamped Groups II III blood samples taken at 120 minutes 360 III. right common femoral IV V V.Results: peak obtained IV. reduced advanced periods ischaemia. In other words, significantly higher two hours (p < 0.05), to...
Background:Calcium dobesilate (CaD) is a member of the synthetic veno-active drug family. Only small number reports are available that describe micro-angiogenic effects CaD in current literature. Material and Methods:The antiangiogenic potential was compared with bevacizumab (Bb), which potent angiogenesis inhibitor, chick chorioallantoic membrane model. Four different concentrations (10–7, 10–6, 10–5, 10–4 M) pellet were prepared for each drug. Changes vessel formation scored according to...
Acute mesenteric ischaemia is an emergency condition that requires urgent and expeditious diagnosis immediate surgical or medical intervention. The initial hours are critical for the recovery of affected bowel segment. Thus, its clinic diagnostic biomarkers important when it comes to reducing mortality morbidity rates.Twenty-four male Sprague-Dawley rats were included in study. divided into three equal groups. Those Group I sacrificed determine basal serum values ischaemia-modified albumin...
Temporal arteritis is systemic vasculitis of medium and large sized vessels. The lowest incidence rates were reported in Turkey, Japan Israel. We aimed to investigate the results patients with biopsy-proven temporal those classified according American College Rheumatology criteria from a low-incidence region for arteritis. our study are noteworthy, since there limited data on pathologic diagnosis Turkey.We studied medical records, laboratory findings such as erythrocyte sedimentation rate...
Although traumatic fistula is frequently encountered, high-output heart failure due to a very rare condition. Despite an indefinitive history of trauma, arteriovenous (AV) may develop insidiously, and therefore identification shunt highly important for treatment.Here we report 46-year-old male patient with femoral developed following penetrating stab injury 17 years ago.Traumatic AV curable cause failure. Also, careful examination the as significant radiological imaging methods.
Objective This study aimed to investigate the effects of melatonin on cardiac oxidative stress and apoptosis in fetal heart RUPP rats.Methods The samples were obtained from administrated ratsResults Our results indicate that preeclampsia exacerbated by deficiency triggers hypoxic conditions, both mis/un-folded protein response, stress-induced DNA damage apoptosis. Melatonin treatment provided significant therapeutic hearts via regulating all these response at cellular molecular...
Chronic venous insufficiency may cause stasis ulcers that significantly impact on the quality of life. Many methods have been described for preventing or treating these ulcers. However, often recur as a result continuing insufficiency. Here we report 30-year-old male patient with chronic He was admitted to hospital owing recurrent had history various flavonoid drug usage and compression therapies over previous six years. Venous Doppler sonography revealed combined saphenofemoral deep femoral...
Background Neurohumoral and hemodynamic mechanisms have an effect on cardiac activity. C-type natriuretic peptide (CNP) is accessible in the cardiovascular system. The aim of this study was to determine whether CNP concentrations pericardial fluid blood are related dysfunction patients undergoing coronary artery bypass graft surgery. Materials Methods In study, 40 grafting were enrolled. separated into two groups according left ventricular (LV) ejection fraction (EF): group 1 contained 28...
Objective: Ginseng is a traditional herbal medicinal product widely used for various types of diseases because its cellular protective effects.Possible effects ginseng were investigated in blood, cardiac and renal tissue samples compared with common anti-aggregant agents an animal ischaemia-reperfusion (I/R) model.Methods: Twenty rats equally divided into four different groups as follows: control group (I/R-induced without drug use), I (acetylsalicylic acid-administered group), II...