A5082957764- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Treatment and Management
- Liver Disease Diagnosis and Treatment
- Bariatric Surgery and Outcomes
- Diabetes Management and Research
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Chronic Kidney Disease and Diabetes
- Diet and metabolism studies
- Hormonal and reproductive studies
- Cardiovascular Health and Disease Prevention
- Metastasis and carcinoma case studies
- Global Cancer Incidence and Screening
- Breast Cancer Treatment Studies
- Blood Pressure and Hypertension Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Employment and Welfare Studies
- Dietary Effects on Health
- Global Health Care Issues
- Cancer Risks and Factors
- Cardiovascular Function and Risk Factors
- Esophageal Cancer Research and Treatment
- Lipoproteins and Cardiovascular Health
- Nutrition and Health in Aging
- Health disparities and outcomes
- Esophageal and GI Pathology
General Hospital of Guangzhou Military Command
2021-2023
To assess the associations of diabetes duration and glycaemic control (defined by plasma glycated haemoglobin [HbA1c] level) with risks cardiovascular disease (CVD) all-cause mortality to determine whether addition either or both established CVD risk factors can improve predictions.A total 435 679 participants from UK Biobank without at baseline were included. Cox models adjusting for classic (sociodemographic anthropometric characteristics, lipid profiles medication use) used, predictive...
Objective: The 2017 American College of Cardiology/American Heart Association blood pressure (BP) guidelines lowered the hypertension threshold from a SBP/DBP level at least 140/90 mmHg to 130/80 mmHg. cardiovascular impact isolated systolic (ISH) and diastolic (IDH) under new definition remains unclear. Methods: We used data UK Biobank study, which is prospective population-based cohort study. Participants were categorized into five groups: normal BP, high ISH, IDH hypertension. primary...
<title>Abstract</title> The proteomic mechanisms bridging pulmonary function and metabolic dysfunction-associated steatotic liver disease (MASLD) remain elusive. Using data (2,920 proteins) from the UK Biobank (n = 47,055), we applied elastic net regression to identify plasma signatures related three lung measures (forced expiratory volume in one second [FEV1], forced vital capacity [FVC], peak flow [PEF]) explored their mediating role function–MASLD associations. All were inversely...
Abstract Background To investigate the influence of diabetes duration and glycemic control, assessed by glycated hemoglobin (HbA1c) levels, on risk incident dementia. Methods The present study is a prospective 461 563 participants from UK Biobank. age at diagnosis was determined self-report. Diabetes calculated as baseline minus diagnosis. Cox proportional hazards regression models were used to estimate hazard ratios (HRs) with 95% confidential intervals (CIs). Results During median...
Purpose: Mammography has been confirmed as the only effective mode to improve prognosis of patients with breast cancer in Western developed countries, but might not be a good choice other areas world. One major challenges China is determine an optimal imaging modality for screening. This study was designed clarify sensitivity ultrasonography compared that mammography rural China. Methods: We retrospectively studied and based on 306 detected by program "screening cervical cancer" performed...
Obesity is associated with adverse health events among diabetic patients, however, the relationship between obesity fluctuation and risk of microvascular complications this specific population unclear. We aimed to examine effect waist circumference (WC) body mass index (BMI) variability on outcome. Annually recorded anthropometric data in Action Control Cardiovascular Risk Diabetes (ACCORD) study was used association WC BMI defined as independent mean, outcomes, including neuropathy,...
Abstract Background Greater lipid variability may cause adverse health events among diabetic patients. We aimed to examine the effect of on risk microvascular outcomes type 2 diabetes mellitus Methods assessed association between visit‐to‐visit (measured by independent mean) in high‐density lipoprotein (HDL) cholesterol, low‐density lipoprotein‐cholesterol (LDL), triglyceride, and remnant cholesterol (RC) measurements participants involved Action Control Cardiovascular Risk Diabetes (ACCORD)...
Background The prevalence of diabetes is on the rise globally coupled with its associated complications, such as diabetic nephropathy (DN). Obesity has been identified a risk factor for development DN but it still unclear which obesity index best predictor incident DN. Methods Data from participants type 2 mellitus (T2DM) in Action to Control Cardiovascular Risk Diabetes (ACCORD) study were used examine sex-specific association between waist circumference (WC), waist-to-height ratio (WHtR),...
Background Lean body mass (LBM) and fat (FM) have been shown to different associations with several chronic diseases but little is known about the sex-specific association of LBM FM diabetic nephropathy (DN) risk among participants diabetes. Methods Participants from Action Control Cardiovascular Risk in Diabetes (ACCORD) study was used a post hoc analysis examine predicted index (LBMI) (FMI) incident DN (defined as composite outcome three types predefined DN). Because sex differences...
Wealth and income are potential modifiable risk factors for dementia, but whether wealth status, which is composed of a combination debt poverty, assessed by income, associated with cognitive impairment among elderly adults remains unknown.To examine the associations different combinations poverty incidence dementia without (CIND) to evaluate mediating role depression in these relationships.We included 15,565 participants aged 51 years or older from Health Retirement Study (1992-2012) who...