A5036278331- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Analytical Chemistry and Chromatography
- Analytical chemistry methods development
- Renal and Vascular Pathologies
- Analytical Methods in Pharmaceuticals
- Microfluidic and Capillary Electrophoresis Applications
- Pesticide Residue Analysis and Safety
- Transplantation: Methods and Outcomes
- Electrochemical Analysis and Applications
- Psychedelics and Drug Studies
- Neuroscience and Neuropharmacology Research
- Phenothiazines and Benzothiazines Synthesis and Activities
- Cancer, Stress, Anesthesia, and Immune Response
- Mass Spectrometry Techniques and Applications
- Poisoning and overdose treatments
- Bone health and osteoporosis research
- Forensic Toxicology and Drug Analysis
- Heavy Metal Exposure and Toxicity
- Cannabis and Cannabinoid Research
- Renal cell carcinoma treatment
- Bone Metabolism and Diseases
- Inflammatory Biomarkers in Disease Prognosis
- Electrochemical sensors and biosensors
Jagiellonian University
2010-2022
Medical University of Warsaw
1989-2019
Institute of Psychiatry and Neurology
2016
Institute of Cardiology
2016
Central Clinical Hospital
2016
John Paul II Hospital
2016
Cracow University of Technology
2016
Health Center
2016
Faculty (United Kingdom)
2015
Wroclaw University of Economics and Business
2013
Abstract 4-Iodo-2,5-dimethoxy- N -(2-methoxybenzyl)phenethylamine (25I-NBOMe) is a new psychoactive substance with strong hallucinogenic properties. Our previous data reported increased release of dopamine, serotonin, and glutamate after acute injections tolerance development in the neurotransmitters rats’ behavior chronic treatment 25I-NBOMe. The recreational use 25I-NBOMe associated severe intoxication deaths humans. There no about vivo toxicity towards brain tissue. In this article...
A critical review of analytical methods for identification and determination some phenothiazine derivatives tricyclic antidepressants in a variety materials is presented. The have been divided into five groups accordingly to the applied techniques: spectrometric, chromatographic, immunoassay, electrochemical, capillary electrophoretic. based on survey chemical toxicological literature covering articles mainly from 2000 until now. brief description physicochemical properties compounds...
Currently, the medical use of food supplements containing Cannabis sativa has attracted interest consumers, as well and scientific community. With increasing consumption these products, there is also a risk their abuse or discrepancy between actual declared contents active substances by manufacturer in products. Thus, development elaboration analytical procedures for determination appropriate phytocannabinoids seems to be important. This work focuses on simple, fast environmentally friendly...
Growing consumer interest in hemp oilseed supplements requires quality control. Therefore, appropriate, effective and verified analytical methods are needed for the determination of some bioactive cannabinoids them. The aim study is to present an extended (compared our previous research) validated high performance liquid chromatography with diode array detection (HPLC-DAD) method four (cannabidiol, cannabidiolic acid, cannabinol delta-9-tetrahydrocannabinol) oil matrix, which was used...
Abstract Cloud-point extraction (CPE) with RP-HPLC/DAD detection was used to develop a screen for six model basic drugs (paracetamol, promazine, amitriptyline, nortriptyline, clomipramine and chlorpromazine) in human plasma. These drugs’ varied hydrophobicities entail different affinities the micelle-rich phase CPE efficiencies. Extraction recovery (except paracetamol) above 80% reproducibility (RSD%) ranged from 2.88 10.26 intraday 3.12 12.33 interday. The limits of were: 0.125 µg mL−1...
Isolation conditions for five pesticides (metazachlor, tebuconazole, λ -cyhalothrin, chlorpyrifos, and deltamethrin) from rape oil samples were examined using the dispersive solid-phase graphene extraction technique. To determine optimal conditions, a number of experimental factors (amount graphene, amount salt, type volume desorbing solvent, desorption time with without sonication energy, temperature during desorption) studied. The compounds interest separated detected by an HPLC-UV...
The current clinical and forensic toxicological analysis of body fluids requires a modern approach to sample preparation characterized by high selectivity enrichment capability, suitability for micro-samples, simplicity speed, the possibility automation miniaturization, as well use small amounts reagents, especially toxic solvents. Most abovementioned features may be realized using so-called microextraction techniques which cover liquid-phase (e.g., single-drop microextraction, SDME;...
The influence of experimental conditions on gradient high-performance liquid chromatography/diode array detector separation and identification 13 psychotropic drugs belonging to two groups--phenothiazines tricyclic antidepressants--was examined. main interaction effects three factors were determined according a 2 3 factorial design, the optimum analysis searched for. degree which chromatographic peaks overlap is taken into account in proposed criterion for quality. screening was tested whole...
A new, effective cloud-point extraction method for the determination of permethrin in human urine was developed.
Abstract Separation and extraction conditions for four atypical neuroleptics (clozapine, N-desmethylclozapine (active metabolite of clozapine), olanzapine, quetiapine) one classical neuroleptic (perazine) in human plasma have been studied. Reverse phase chromatography (RP-18) with the mobile consisted of: A. aq. orthophosphoric acid addition N,N,N′,N′-tetramethylethylendiamine (TEMED), pH = 5.0, B. acetonitrile, gradient flow, was selected. As optimal liquid-liquid conditions, sample 11.6,...