A5009796917- Synthesis and biological activity
- Computational Drug Discovery Methods
- Synthesis and Biological Evaluation
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis of heterocyclic compounds
- Multicomponent Synthesis of Heterocycles
- Click Chemistry and Applications
- Cholinesterase and Neurodegenerative Diseases
- Quinazolinone synthesis and applications
- Tryptophan and brain disorders
- Phenothiazines and Benzothiazines Synthesis and Activities
- Malaria Research and Control
- Peptidase Inhibition and Analysis
- Diabetes Treatment and Management
- Chemical Synthesis and Analysis
- Synthesis and Reactions of Organic Compounds
- Synthesis of Organic Compounds
- Organic Chemistry Synthesis Methods
- Inflammatory mediators and NSAID effects
- Bioactive Compounds and Antitumor Agents
- Research on Leishmaniasis Studies
- Neuroinflammation and Neurodegeneration Mechanisms
- Synthesis and Characterization of Pyrroles
- Synthesis and Reactivity of Sulfur-Containing Compounds
- Diverse Scientific Research Studies
Jamia Hamdard
2016-2025
Shahjalal University of Science and Technology
2023
King Saud University
2013-2023
Fiji National University
2021
Delhi Pharmaceutical Science and Research University
2016-2020
Hybrid Energy (Norway)
2018
Bhagwant University
2015
Pakistan Institute of Engineering and Applied Sciences
2015
Creative Commons
2013
National University of Malaysia
2013
Quinoline or 1-aza-naphthalene is a weak tertiary base. ring has been found to possess antimalarial, anti-bacterial, antifungal, anthelmintic, cardiotonic, anticonvulsant, anti-inflammatory, and analgesic activity. not only wide range of biological pharmacological activities but there are several established protocols for the synthesis this ring. The article aims at highlighting these very diversities
Abstract Benzimidazole, the benzo derivative of imidazole, is a class bicyclic aromatic organic compound consisting six‐membered benzene ring fused to five‐membered imidazole at 4‐ and 5‐positions ring. It vital pharmacophore many biologically active heterocyclic compounds with variety pharmacological activities. Over time, benzimidazole its derivatives have evolved as vibrant systems due their potency in wide range bioactive like analgesics, antifungals, anti‐inflammatory,...
Synthesis, anticonvulsant and toxicity evaluation of 2-(1H-indol-3-yl)acetyl-N-(substituted phenyl)hydrazine carbothioamides their related heterocyclic derivativesA series new 5-(1H-indol-3-yl)methyl-4-(substituted aryl)-2,4-dihydro-3H-1,2,4-triazole-3-thiones (4a-g), 5-(1H-indol-3-yl)methyl-N-(substituted aryl)-1,3,4-oxadiazol-2-amines (5a-g) aryl)-1,3,4-thiadiazol-2-amines (6a-g) were prepared by treating phenyl) hydrazine (3a-g) with suitable reagents. All the newly synthesized compounds...
Pharmacophore modeling, molecular docking, and in silico ADME studies have been carried out to determine the binding mode drug likeliness profile of acyl 1,3,4-thiadiazole amides sulfonamides as antitubulin agents. A four point pharmacophore model (AAHR.11) was generated using 63 compounds with IC50 values ranging from 3.16 505.76 μM. statistically significant 3D-QSAR hypothesis. The had a high correlation coefficient (R2 = 0.8925), cross validation (Q2 0.8204) F value (44.3) at 6 component...