A5115467748- X-ray Diffraction in Crystallography
- Crystallization and Solubility Studies
- Magnetism in coordination complexes
- Organometallic Complex Synthesis and Catalysis
- Metal complexes synthesis and properties
- Synthesis and characterization of novel inorganic/organometallic compounds
- Chemical Reaction Mechanisms
- Surface Chemistry and Catalysis
- Synthesis and Properties of Aromatic Compounds
- Lanthanide and Transition Metal Complexes
- Chemotherapy-induced organ toxicity mitigation
- Chemotherapy-induced cardiotoxicity and mitigation
- Crystallography and molecular interactions
- Chemical Synthesis and Characterization
- Hormonal Regulation and Hypertension
- Analytical Methods in Pharmaceuticals
- N-Heterocyclic Carbenes in Organic and Inorganic Chemistry
- Child Development and Education
- Advanced Drug Delivery Systems
- Chronic Myeloid Leukemia Treatments
- Attention Deficit Hyperactivity Disorder
- Supramolecular Chemistry and Complexes
- Drug Solubulity and Delivery Systems
- Parkinson's Disease Mechanisms and Treatments
- Coenzyme Q10 studies and effects
Uppsala University
2024
University of Göttingen
2023
Indian Institute of Technology Bombay
2016-2022
Jamia Hamdard
2018-2021
University of Mumbai
2017
Myocardial infarction (MI) remains a major cause of morbidity and mortality worldwide. Nimodipine is calcium (Ca2+) channel blocker as well PDE1 inhibitor primarily used in subarachnoid haemorrhage (SAH) due to its blood-brain barrier crossing property. vinpocetine inhibit the degradation phosphodiester bond which increases cGMP cAMP levels causing vasodilation.We have divided rats randomly into Group I - Vehicle control; II Toxic control (ISO 85 mg/kg, i.p.); III, IV V (5, 10 15 i.p....
Abstract Thiele's Hydrocarbons (THs) featuring a 9,10‐anthrylene core with switchable geometric and electronic configurations offer exciting possibilities in advanced functional materials. Despite significant advances main group‐based diradicaloids contemporary chemistry, group THs containing an anthrylene cores have remained elusive, primarily due to the lack of straightforward synthetic strategies inherent high reactivity these species. In this study, we utilize anthracene‐based phosphine...
The dinuclear complexes {(μ-H2L)[Ru(bpy)2]2}(ClO4)2 ([3](ClO4)2), {(μ-H2L)[Ru(pap)2]2}(ClO4)2 ([4](ClO4)2), and the asymmetric [(bpy)2Ru(μ-H2L)Ru(pap)2](ClO4)2 ([5](ClO4)2) were synthesized via mononuclear species [Ru(H3L)(bpy)2]ClO4 ([1]ClO4) [Ru(H3L)(pap)2]ClO4 ([2]ClO4), where H4L is centrosymmetric 1,5-diamino-9,10-anthraquinone, bpy 2,2'-bipyridine, pap 2-phenylazopyridine. Electrochemistry of structurally characterized [1]ClO4, [2]ClO4, [3](ClO4)2, [4](ClO4)2, [5](ClO4)2 reveals...
5,7,12,14-Tetraazapentacene-6,13-quinone (L) reacts with 2 equiv of [Ru(acac)2(CH3CN)2] to form two linkage isomeric bis(chelate) compounds, [{RuII(acac)2}2(μ-L)], blue 1, 5,6;12,13 coordination and violet 5,6;13,14 coordination. The isomers could be separated, structurally characterized in crystals as rac diastereomers (ΔΔ/ΛΛ), studied by voltammetry (CV, DPV), EPR, UV-vis-NIR spectroelectrochemistry (meso-1, rac-2). DFT TD-DFT calculations support the structural spectroscopic results...
The doubly deprotonated bridging ligand L12- derived from 2,6-bis(2-pyridyl)-1,5-dihydro-1',4'-benzoquinono[2',3'-d:5',6'-d']diimidazole H2L1 forms coordination compounds with two bis(2,2'-bipyridine)osmium(II) complex fragments in anti ([1](ClO4)2) and syn configurations ([2](ClO4)2) of {(μ-L1)[Os(bpy)2]2}(ClO4)2, as evident crystal structure analyses. Exchange the metal-coordinating 2-pyridyl functions bridge through non-coordinating 4-tolyl substituents (L12- → L22-) leads to [3](ClO4)2...
The redox-active ligand 5,7,12,14-tetraazapentacene-6,13-quinone = L forms structurally characterised compounds with three (1) or four (2) [Ru(acac)2] complex fragments in which each of the metals is N,O-chelated. new tris- and tetrakis-bidentate chelate exhibit ruthenium centres bridged at about 4 Å by quinone O atoms are then situated across pentacene π system 6-8 distance. Several electron transfer processes were observed voltammetry (CV, DPV) intermediates identified EPR UV-Vis-NIR...
Abstract After double deprotonation, 2,6‐diaryl‐ p ‐benzoquinonodiimidazoles (aryl=4‐tolyl ( I ) or 2‐pyridyl II )) were shown to bridge two [Ru(bpy) 2 ] 2+ (bpy=2,2 ′ ‐bipyridine) complex fragments through the imidazolate N and ‐quinone O → 1 pyridyl donor atoms ). Characterization by crystal structure analysis, H/ 13 C NMR spectroscopy, cyclic differential pulse voltammetry, spectroelectrochemistry (UV/Vis/NIR, IR, EPR) in combination with TD‐DFT calculations revealed surprisingly...
π-Conjugated bridged isomeric diruthenium(II) complexes [(acac)2RuII(μ-DIPQD)RuII(acac)2], 1 (trans) and 2 (cis) (acac– = acetylacetonate, (8E,16E)-N8,N16-diphenylindeno[1,2-b]indeno[2′,1′:5,6]pyrazino[2,3-g]quinoxaline-8,16-diimine (trans-DIPQD), (12E,16E)-N12,N16-diphenylindeno[1,2-b]indeno[1′,2′:5,6]pyrazino[2,3-g]quinoxaline-12,16-diimine (cis-DIPQD) were separated structurally characterized. The structures of the rac (ΔΔ/ΛΛ) forms exhibit two units {Ru(acac)2}, linked to adjacent...
The development of DPPP2- (H2DPPP = 2,5-dihydro-3,6-di-2-pyridylpyrrolo(3,4-c)pyrrole-1,4-dione) bridged (NN∩NN) diruthenium complexes [(Cym)(X)RuII(μ-dppp)RuII(X)(Cym)] (Cym para-cymene and X OTf- (1), SCN- (2), N3- (3), NO2-(4)) are considered as the probable molecular clips for construction metallarectangle. Crystal structures 2-4 established anticonfiguration with respect to monodentate SCN-, NO2- groups, respectively. Though failed provide desired metallarectangle in combination...
Abstract Thiele's Hydrocarbons (THs) featuring a 9,10‐anthrylene core with switchable geometric and electronic configurations offer exciting possibilities in advanced functional materials. Despite significant advances main group‐based diradicaloids contemporary chemistry, group THs containing an anthrylene cores have remained elusive, primarily due to the lack of straightforward synthetic strategies inherent high reactivity these species. In this study, we utilize anthracene‐based phosphine...
The stepwise reduction of the highly contorted truxene‐based triphosphaalkene 1 using KC8 led to isolation mono‐, di‐and tri‐anionic species. solid‐state molecular structures mono‐ and diradical anionic species were elucidated by single crystal X‐ray diffractions, revealing elongated P‐C bonds a pronounced “indene” aromatization compared parent system. All three radical displayed distinct Electron Paramagnetic Resonance (EPR) spectra, providing compelling evidence for open‐shell electronic...
The stepwise reduction of the highly contorted truxene‐based triphosphaalkene 1 using KC8 led to isolation mono‐, di‐and tri‐anionic species. solid‐state molecular structures mono‐ and diradical anionic species were elucidated by single crystal X‐ray diffractions, revealing elongated P‐C bonds a pronounced “indene” aromatization compared parent system. All three radical displayed distinct Electron Paramagnetic Resonance (EPR) spectra, providing compelling evidence for open‐shell electronic...
This experimental and theoretical study illustrates how phosphaalkenes, which are isolobal to alkenes, can utilize a variety of external triggers for molecular switching. The E/Z isomerization truxene‐based phosphaalkene, i.e. TruxC=P‐Mes* (Mes* = 2,4,6‐tris‐t‐butyl‐benzene), is accomplished by irradiation, metal coordination, or deprotonation the truxene core. reversible quantitative Z/E double bond gold(I) coordination/decoordination phosphorous lone pair represents novel fuelling strategy...
Abstract Herein we report the reactions of 3,4,5,6‐tetrafluoroterephthalonitrile ( 1 ) with bis(silylene) and bis(germylene) LE−EL [E=Si 2 Ge( 3 ): L=PhC(N t Bu) )]. The reaction LSi−SiL (L=PhC(N two equivalents resulted in an unprecedented oxidative addition a C−F bond leading to disilicon(III) fluoride {L(4‐C 8 F N)FSi−SiF(4‐C N)L}( 4 ), wherein Si−Si single was retained. In contrast, LGe−GeL one equivalent cleavage Ge−Ge L(4‐C N )Ge 5 LGeF 6 ). All three compounds – were characterized by...
Evaluate the effectiveness of play activities on Inattention, Hyperactivity, Impulsivity and Anxiety in ADHD children age group 6–12 yrs. The objectives this study is Formulation treatment protocol based evaluate yrs with ADHD. It was Pre Post Experimental Design. In which Two were formed according to age, 16 1 14 2. assessment done basis rating Scale & Spence Children Scale. Treatment given each subject. same subject after completing 15 sessions. outcome measures used Rating (SCAS). Results...