A5023024286- Alzheimer's disease research and treatments
- Natural Antidiabetic Agents Studies
- Diabetes Treatment and Management
- Chemotherapy-induced organ toxicity mitigation
- Pharmacological Effects of Natural Compounds
- Nigella sativa pharmacological applications
- Chemotherapy-induced cardiotoxicity and mitigation
- Cholinesterase and Neurodegenerative Diseases
- Drug-Induced Hepatotoxicity and Protection
- Cardiac Ischemia and Reperfusion
- Bioactive Compounds and Antitumor Agents
- Computational Drug Discovery Methods
- Advancements in Transdermal Drug Delivery
- Pharmacology and Obesity Treatment
- Natural product bioactivities and synthesis
- Pharmacological Effects of Medicinal Plants
- Tryptophan and brain disorders
- Curcumin's Biomedical Applications
- Stress Responses and Cortisol
- Hormonal Regulation and Hypertension
- Genomics, phytochemicals, and oxidative stress
- Synthesis and biological activity
- Saffron Plant Research Studies
- Medicinal Plants and Neuroprotection
- Renin-Angiotensin System Studies
Jamia Hamdard
2016-2025
Delhi Pharmaceutical Science and Research University
2023
Hamdard University
2004-2014
Medical University of Graz
2012
Leiden University Medical Center
2012
Institute of Cardiology
2012
Sanjay Gandhi Post Graduate Institute of Medical Sciences
2012
University College London
2012
Charles University
2012
Diabetes mellitus is a complicated metabolic disorder that has gravely troubled the human health and quality of life. Conventional agents are being used to control diabetes along with lifestyle management. However, they not entirely effective no one ever been reported have fully recovered from diabetes. Numerous medicinal plants for management in various traditional systems medicine worldwide as great source biological constituents many them known be against Medicinal antihyperglycemic...
With the constant failure of clinical trials continuous exploration a therapeutic target against Alzheimer's disease (AD) is utmost need. Numerous studies have supported hypothesis that central insulin resistance plays significant role in AD. Serine phosphorylation Insulin Receptor Substarte-1 (IRS-1) has been found to be contributing factor neuronal resistance. Astaxanthin (ASX) xanthophyll carotenoid which previously demonstrated antidiabetic and neuroprotective actions. In present study,...
Diabetic kidney disease (DKD) is a major public health problem characterized by elevated urine albumin excretion or reduced glomerular filtration rate both. The pathophysiology of DKD involves various pathways like hemodynamic, metabolic, and inflammatory pathways. Increase in reactive oxygen species formation induced hyperglycemia through activation electron transport chain considered as the initiators development diabetes complications. Prevalence raising continuously with disparate growth...
Diabetes and hypertension are the two major causes of chronic kidney disease (CKD). Epidemiological studies have found poor knowledge about CKD among general population. Hence, this study aimed to assess awareness type 2 diabetes mellitus (T2DM) patients in India. Patients with confirmed T2DM were included study. receiving dialysis or a history transplant excluded. A validated questionnaire was used CKD. Demographic characteristics presented using descriptive statistics trends groups...
Carica papaya Linn. (Caricaceae) leaf (CPL) juice has long been traditionally used in ethnomedicine for dengue fever.The study examines the effects of standardized CPL aqueous extract (SCPLE) on platelet count, extramedullary haematopoiesis (EMH), and immunomodulation cyclophosphamide (CP)-induced animal model thrombocytopenia.The was analyzed myricetin, caffeic acid, trans-ferulic kaempferol using HPTLC standardization followed by UPLC-qTOF/MS fingerprinting metabolite signature. The SCPLE...
Objectives: The present study was designed to evaluate the cardioprotective potential of edaravone on oxidative stress, anti-apoptotic, anti-inflammatory and ultrastructure findings in isoproterenol (ISO) induced myocardial infarction (MI) rats.Methods: Rats were pretreated with (1, 3, 10 mg/kg body weight-1 day-1) intraperitoneally. MI by subcutaneous administration ISO (85 weight-1) at two doses 24h interval.Results: treated rats showed significant increase levels thiobarbituric acid...
Cyclophosphamide (CP) is commonly used as antineoplastic and immunosuppressant drug with noticeable gonadotoxic profile. Nerolidol (NER) a sesquiterpene potent antioxidant anti-inflammatory properties. Thus, the present study was designed to explore its possible gonadal protective potential against cyclophosphamide-induced testicular, epididymal, seminal spermatozoal toxicities. Animals were divided into five groups: control (normal saline for 14 days), treatment group (NER 200 400 mg/kg,...