- Nanoparticles: synthesis and applications
- Carbon Nanotubes in Composites
- Nanopore and Nanochannel Transport Studies
- Graphene and Nanomaterials Applications
- Recycling and Waste Management Techniques
- Bone Tissue Engineering Materials
- Electrochemical Analysis and Applications
- Healthcare and Environmental Waste Management
- Catalytic Cross-Coupling Reactions
- Microplastics and Plastic Pollution
- Arsenic contamination and mitigation
- Heavy Metal Exposure and Toxicity
- Nanotechnology research and applications
- Nanomaterials for catalytic reactions
- Effects and risks of endocrine disrupting chemicals
- Electrocatalysts for Energy Conversion
- Copper Interconnects and Reliability
- Membrane Separation Technologies
- Ion-surface interactions and analysis
- Fullerene Chemistry and Applications
- Environmental remediation with nanomaterials
- Anesthesia and Neurotoxicity Research
- Membrane Separation and Gas Transport
- Metallurgical and Alloy Processes
- Recycling and utilization of industrial and municipal waste in materials production
United States Food and Drug Administration
2015-2023
Center for Food Safety and Applied Nutrition
2015-2019
New Jersey Institute of Technology
2010-2018
We developed a dispersal method for multiwalled carbon nanotubes (MWCNTs) that allows quantitative assessment of dispersion on profibrogenic responses in tissue culture cells and mouse lung. demonstrate the as-prepared (AP), purified (PD), carboxylated (COOH) MWCNTs by bovine serum albumin (BSA) dipalmitoylphosphatidylcholine (DPPC) influences TGF-β1, PDGF-AA, IL-1β production vitro vivo. These biomarkers were chosen based their synergy promoting fibrogenesis cellular communication...
Background: Differences in interlaboratory research protocols contribute to the conflicting data literature regarding engineered nanomaterial (ENM) bioactivity.Objectives: Grantees of a National Institute Health Sciences (NIEHS)-funded consortium program performed two phases vitro testing with selected ENMs an effort identify and minimize sources variability.Methods: Consortium participants (CPPs) conducted ENM bioactivity evaluations on zinc oxide (ZnO), three forms titanium dioxide (TiO2),...
In vivo studies have demonstrated that the state of dispersion carbon nanotubes (CNTs) plays an important role in generating adverse pulmonary effects. However, little has been done to develop reproducible and quantifiable techniques conduct mechanistic vitro. This study was evaluate multiwalled (MWCNTs) tissue culture media, with particular emphasis on understanding forces govern agglomeration how modify these forces. Quantitative such as hydrophobicity index, suspension stability...
This study presents the removal of trace level arsenic to meet drinking water standards using an iron oxide-multi-walled carbon nanotube (Fe-MWCNT) hybrid as a sorbent. The synthesis was facilitated by high degree functionalization microwave assisted process, and controlled assembly oxide possible where MWCNT served effective support for oxide. In final product, 11 % atoms were attached Fe. Fe-MWCNT in below standard levels 10 µg L(-1). absorption capacity composite 1723 g(-1) 189 As(III)...
The potential for consumer exposure to nano-components in food contact materials (FCMs) is dependent on the migration of nanomaterials into food. Therefore, characterising physico-chemical properties and constituents an important step assessing safety FCMs. A number commercially available storage products, purchased domestically within United States internationally, that claim contain nanosilver were evaluated. products made polyethylene, polypropylene polyphenylene ether sulfone all...
We demonstrate the implementation of multiwalled carbon nanotubes-fullerene (MWNT-C60) complexes in bulk heterojunction organic photovoltaic (OPV) cells. Such a design takes advantage C60 as an electron acceptor, while MWNTs serve efficient charge transporters. Two types chemically functionalized were used to synthesize these complexes. The first carboxylated nanotubes (c-MWNT), latter with octadecylamine (o-MWNT). All parameters found be superior c-MWNT, and their combined effect led eight...
Research focused on assessing potential consumer exposure to nanoparticles released from nano-enabled food-contact materials (FCMs) has often reached conflicting conclusions regarding the detection of migrating nanoparticles. These conclusions, coupled with for be unstable in certain food simulants, necessitated a closer look at role played by simulants recommended use nanoparticle migration evaluation. The influence aqueous under evaluation conditions is reported herein. stability silver...
The size dependent colloidal behavior of aqueous dispersions carboxylated multiwall carbon nanotubes (c-MWCNTs) is presented. presence carboxylic groups provided electrostatic stabilization in water, where the affected agglomeration. While aspect ratio did not show any definite correlation, hydrophobicity indices (HI), zeta potential and aggregation kinetics showed dependence on length c-MWCNTs shorter significantly lower HI values, smaller particle aggregates, higher values critical...
To assess the biological effects of low level, water dispersible, functionalised carbon nanotube (f-CNT) exposure in an vitro model simulating digestive tract, cellular protein expression was quantified and compared using label-free quantitative mass spectrometry (LFQMS).Co-cultured cells were exposed to well-characterised SWCNT-COOH, MWCNT-COOH, MWCNT-PVP.The relative 2,282 unique proteins across dose groups.428 found be differentially expressed.At high dose, extent differential...
Migration evaluation involving nano-enabled food contact materials (FCMs) mostly focuses on potential nanoparticle release from new unused products. This may not represent consumer use practices encountered by the FCMs in their lifecycle. In order to determine if product impacts of nanoparticles or other FCM components, it is necessary perform migration evaluations under typical scenarios. A quantitative assessment a commercially available nanosilver-enabled cutting board was performed five...
Background/Methods Increased use and sales of e-cigarettes raises concerns about the potential environmental impacts throughout their life-cycle. However, few available research studies focus on ecotoxicity e-cigarettes. In this study, we short-list e-liquid chemicals from published literature that should be considered in future impact risk assessments. We used a combination laboratory bioassays-based data predictive methods (eg, Structure-Activity Relationships) to characterise hazards...
Functional barriers in food contact materials (FCMs) are used to prevent or reduce migration from inner layers multilayer structures food. The effectiveness of functional barrier was investigated coloured polystyrene (PS) bowls due their intended condition use with hot liquids such as soups stew. Migration experiments were performed over a 10-day period using USFDA-recommended simulants (10% ethanol, 50% corn oil and Miglyol) along several other oils. At the end 10 days, solvent dyes had...
Potential consumer exposure to nanoparticles (NPs) from nanoenabled food contact materials (FCMs) has been a driving force for migration studies of NPs FCMs. Although NP fresh, unused FCMs was not previously observed, conditions that result in significant changes the surface have investigated into food. Therefore, quantitative assessment nanoparticle release commercially available nanosilver-enabled performed using an abrasion protocol simulate cleaning, cutting, scraping and other stressful...
Carbon nanotubes (CNTs) are effective supports for nanometals and together they represent hybrids that combine the unique properties of both. A microwave-induced reaction was used to deposit nanopalladium on carboxylated octadecylamine functionalized multiwall CNTs, which were carry out C-C coupling reactions in dimethylformamide (DMF) toluene. These showed excellent catalytic activity with yield as high 99.8%, while its enhancement respect commercially available Pd/C catalyst reached 109%,...