Wojciech Pawlak

ORCID: 0000-0001-6461-523X
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About
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Research Areas
  • Metal and Thin Film Mechanics
  • Advanced materials and composites
  • Diamond and Carbon-based Materials Research
  • Craniofacial Disorders and Treatments
  • Technical Engine Diagnostics and Monitoring
  • Orthodontics and Dentofacial Orthopedics
  • dental development and anomalies
  • Tribology and Wear Analysis
  • Oral and Maxillofacial Pathology
  • Cleft Lip and Palate Research
  • Advancements in Materials Engineering
  • Mechanical and Thermal Properties Analysis
  • Sinusitis and nasal conditions
  • Head and Neck Surgical Oncology
  • Engine and Fuel Emissions
  • Bone Tumor Diagnosis and Treatments
  • Temporomandibular Joint Disorders
  • Bone health and treatments
  • Cancer Diagnosis and Treatment
  • Cutaneous Melanoma Detection and Management
  • Management of metastatic bone disease
  • Melanoma and MAPK Pathways
  • Advanced Glycation End Products research
  • Intermetallics and Advanced Alloy Properties
  • Textile materials and evaluations

Poznan University of Medical Sciences
2025

University of Warsaw
2023-2024

Lodz University of Technology
2013-2024

Ministry of Interior and Administration
2023

Instytut Techniczny Wojsk Lotniczych
2012-2019

Wroclaw Medical University
2013-2019

National Centre for Nuclear Research
2018

Næstved Sygehus
2017

University of Wrocław
2017

AGH University of Krakow
2015

This study presents new findings related to the incorporation of MXene phases into ceramic. Aluminium oxide and synthesised Ti3C2 were utilised as starting materials. Knowing tendency MXenes oxidation degradation, particularly at higher temperatures, structural modifications proposed. They consisted creating metallic layer on Ti3C2, by sputtering titanium or molybdenum. To prepare composites, powder metallurgy spark plasma sintering (SPS) techniques adopted. In order evaluate effectiveness...

10.3390/ma14040829 article EN Materials 2021-02-10

Adult-type diffuse gliomas are characterized by inevitable recurrence and very poor prognosis. Novel treatment options, including multimodal drugs or effective drug combinations, therefore eagerly awaited. Tinostamustine is an alkylating histone deacetylase inhibiting molecule with great potential in cancer treatment. Thus, the aim of this study was to investigate its effects on glioma cells. In context, tinostamustine evaluated monotherapy as a combination therapy, either celecoxib...

10.3390/ijms26020661 article EN International Journal of Molecular Sciences 2025-01-14

Diabetes is known to involve oxidative stress. However, data on stress in diabetic nephropathy scant. The aim of this study was examine lipid peroxidation and activities key antioxidant enzymes non-insulin dependent diabetes (NIDDM) without those with nephropathy.Twenty-one NIDDM outpatients obvious (persistent proteinuria, over 0.5 g/day albumin excretion 200 microg/min), 14 a long history but hypertension normal urinary rate (<20 microg/min) 19 healthy persons were studied. Malondialdehyde...

10.1093/ndt/13.11.2829 article EN Nephrology Dialysis Transplantation 1998-11-01

The effect of aminoguanidine (AG) on the malondialdehyde (MDA) concentration and activities superoxide dismutase (SOD), catalase glutathione peroxidase (GSH-Px) in erythrocytes rats with streptozotocin-induced diabetes was studied. Induction resulted an increase MDA decreases SOD after 6 12 weeks. GSH-Px activity increased weeks returned to control values AG administration did not affect body weight, blood glucose level HbA1c content diabetic but led a decrease treatment, no significant...

10.1515/cclm.1998.137 article EN Clinical Chemistry and Laboratory Medicine (CCLM) 1998-10-13

Adrenocortical carcinoma (ACC) is a rare disease with poor response to chemotherapy. Cisplatin the most widely investigated drug in treatment of ACC and vitro studies have indicated activity taxanes. The objectives this study were evaluate efficacy toxicity cisplatin combined docetaxel as first-line advanced ACC. Patients included phase II trial investigating combination (50 mg m−2) (60 administered 3-week interval. Nineteen patients study. rate was 21% (95% CI: 3–39%). No obtained complete...

10.1038/bjc.2013.229 article EN cc-by-nc-sa British Journal of Cancer 2013-05-01

Unilateral condylar hyperplasia (UCH) is a rare cause of asymmetrical mandibular overgrowth because the presence an atypical growth in affected condyle. SPECT (single-photon emission computed tomography) can easily establish atypical, prolonged exceeding far beyond normal and activity. A CT, CBCT, or LDCT (computed tomography, cone-beam low-dose confirm diagnosis by evaluating scope bone overgrowth, basis/ramus asymmetry, tendency to head enlargement, changes density, occurrence differences...

10.3390/diagnostics14101014 article EN cc-by Diagnostics 2024-05-15

Corneous skin appendages are not only common and diverse in crown-group amniotes but also present some modern amphibians. This raises the still unresolved question of whether ability to form corneous is an apomorphy a ancestor amphibians or evolved independently both groups. So far, there no palaeontological contribution issue owing lack keratin soft tissue preservation Palaeozoic anamniotes. New data provided by recently discovered ichnofossil specimen from early Permian Poland that shows...

10.1098/rsbl.2024.0041 article EN Biology Letters 2024-05-01

This article describes the manufacturing of alumina composites with addition titanium aluminum carbide Ti3AlC2, known as MAX phases. The were obtained by powder metallurgy technique three types mill (horizontal mill, attritor and planetary mill), consolidated use Spark Plasma Sintering method at 1400 °C, dwelling time 10 min. influence Ti3AlC2 phase on microstructure mechanical properties was analyzed. structure after sintering process also investigated. chemical composition analysis showed...

10.3390/ma15196909 article EN Materials 2022-10-05

The aim of this study was to determine the antitumour activity and toxicity thalidomide in patients with metastatic melanoma. Between July 1999 2001, 20 melanoma were enrolled into study. Patients required have progressive disease following standard therapies (unless there a known contraindication for their usage) be free from symptomatic brain metastases. Thalidomide administered orally at starting dose 200 mg/day, increments 100 mg every 7 days maximum 800 mg/day. experiencing intolerable...

10.1097/00008390-200402000-00009 article EN Melanoma Research 2004-02-01

Nowadays heavy metals in the environment and everyday life are very common.Their usage influence industry is essential.Quite often not only but also general human health might be impacted by their use presence.Metal poisoning its effect on living structures tissues impacts condition.The every species it heavily vulnerable to any metal exposure lead catastrophic natural disasters.In humans skin irritations diseases so common, they do appear, everyone should aware of this.In this paper we...

10.15244/pjoes/39551 article EN Polish Journal of Environmental Studies 2015-01-01
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