One of the most common diseases old age in modern societies is glaucoma. It strongly connected with increased intraocular pressure (IOP) and could permanently damage vision affected eye. As there are only a limited number chemical compounds that can decrease IOP as well blood flow eye vessels, up-to-date investigation new molecules important. The composition dried Cornelian cherry (Cornus mas L.) polar, iridoid-polyphenol-rich fraction was investigated. Loganic acid (50%)...

Presbyopia is a global problem with an estimated 1.3 billion patients worldwide. In the area of functional food applications, dietary supplements or herbs, there are very few reports describing positive effects their use. available literature, lack studies in humans as well on animal model extracts containing, simultaneously, compounds from polyphenol group (in particular, anthocyanins) and iridoids, so we undertook study preparation composed these condition organ vision. Our previous...

Nowadays heavy metals in the environment and everyday life are very common.Their usage influence industry is essential.Quite often not only but also general human health might be impacted by their use presence.Metal poisoning its effect on living structures tissues impacts condition.The every species it heavily vulnerable to any metal exposure lead catastrophic natural disasters.In humans skin irritations diseases so common, they do appear, everyone should aware of this.In this paper we...

The aim of this study was to assess the influence propranolol, nebivolol, and carvedilol on intraocular pressure blood flow in vessels rabbit's (New Zealand White) eyeball.The carried out New white rabbits. Intraocular measured with applanation tonometer Möller-Wedel Icare; Doppler Laser Blood Flow Monitor MBD3.Following a single administration into conjunctival sac, all drugs decreased pressure. Iris following propranol, but increased by nebivolol carvedilol. After repeated oral an IOP...

Hemp is used as a source of fiber, oil and bioactive substances including volatile cannabinoid-containing substances. This paper presents, for the first time, results on evaluation drying methods (convective, vacuum-microwave combined convective pre-drying finishing drying) hemp leaves qualitative quantitative changes in secondary metabolites, essential oils, cannabinoids sterols. A ranking descriptive test was also performed. Drying kinetics presented using three models, logarithmic,...

Glaucoma is a group of eye diseases which result in damage to the optic nerve and vision loss. The most important examination glaucoma patients visual field assessment. One newer perimeters Heidelberg Edge Perimeter (HEP).The aim study was compare measurements made with Humphrey II 740 Visual Field (Carl Zeiss Meditec) (HEP) (Heidelberg Engineering). FDF stimulus (flicker defined form) HEP stimulates magnocellular retinal cells, are first be damaged early stage glaucoma. Even small loss...

Purpose Ocular hypertension became a serious problem in population with increasingly longer life expectancy. Although there are available effective and well established drugs each group possess their disadvantages. In European medicine according to Pharmacopoeia (EP) herbal affected on the eye condition margin of purely chemical treatment. A few them as an active ingredients biologically terpenoids called iridoids. The loganic acid is iridoid Cornelian cherry (Cornus mas) fruits main...

Drugs in ophthalmology are most often applied topically the conjunctival sac. All preparations administered through this route must meet specific requirements and, therefore, not just a simple solution or suspension of drug water. In addition to therapeutic substance, eye drops contain various additives: buffers, preservatives, stabilisers, antioxidants, and isotonic substances increase solubility viscosity. Excipients essential components drugs that determine their quality properties can...

Deer antler is the only mammalian organ that can fully grow back once lost from its pedicle. Antler regeneration a stem cell-based process. Therefore, antlers probably offer most pertinent model for studying in mammals. Evaluation of effect deer cells on healing superficial and deep rabbit corneal wounds was performed. Thirty-six New Zealeand White rabbits were used this study denaturation models, erosion performed with n-heptanol placed cornea 30 NaOH 90 s. drop formulation hyaluronate...

Purpose There are many possibly cause of disturbances the injured cornea epithelization, like for example corneal limbal stem-cell deficiency, diabetes. Growing antlers constitute a model organ examining regeneration processes tissues because they only mammalian appendages capable regeneration. Methods New Zealand White rabbits were used, one eye each animal was treated, and fellow control. Erosion epithelium performed: after local anesthesia 3 mm diameter disc soaked in n-heptanol placed on...

Goldmann tonometer intraocular pressure measurement was described in 1957, and is still the standard method use. However, its limitations were basis of numerous studies aimed to develop a new device whose dependence on factors such as thickness other characteristics cornea would be kept minimum. Currently, different devices are tested that do not only measure pressurebut also define parameters may useful daily practice ophthalmology. These include non-contact applanation (ORA, Ocular...

Research efforts to develop effective and safe antiglaucoma drugs have been ongoing for many years. The cornerstone of treatment is still baroprotection, as this virtually the only method available protect optic nerve slow glaucoma progression, which can be easily controlled by an ophthalmologist. also being conducted in direction neuroprotection, where new compounds are evaluated, well those that used years adjunctive treatments. greatest hope lies gene therapy, has problems solved, but it...

Środki antyseptyczne są grupą substancji szeroko stosowaną w okulistyce od wielu lat. Mają ugruntowaną pozycję, zwłaszcza zapobieganiu zakażeniom okołooperacyjnym. Do odkażania standardowo wykorzystuje się 5% roztwór powidonu jodyny do worka spojówkowego. Jest on uznawany za najskuteczniejszą metodę antyseptyki przedoperacyjnej. U pacjentów z alergią na jod zalecany jest 0,05% chlorheksydyny. Istnieją także próby stosowania innych środków antyseptycznych oraz antybiotyków profilaktyce...

Fluoroquinolones currently used in ophthalmology are effective the treatment of bacterial infections anterior segment eye. The therapeutic effect is usually visible after 2–3 days treatment, they generally well tolerated by patients, and rarely cause allergic reactions. choice right not always simple clear, even when we sure presence infection a patient. There well-known factors that take into consideration, recommending patient to be treated: appearance inflammation, patient’s discomfort,...

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  Despite many methods of treating glaucoma, we still cannot affect all causes this disease. Therefore, substances with different mechanisms action are investigated. Recently, 3 drugs have been introduced to the treatment: citicoline, netarsudil and latanoprost bunod, which will be discussed in article. &nbsp

The aim of the research was to compare intraocular pressure value (IOP) measured with a GAT (Goldmann tonometer) cornea compensated IOP obtained an ORA tonometer, and establish whether there is correlation between IOP, corneal hysteresis OCT RNFL results. Patients were divided into two groups: healthy individuals, no ophthalmic history, patients early primary open angle glaucoma, treated pharmacologically history either laser nor surgical eye treatment. inclusion criteria assessed based on...