Cintia Konjuh

ORCID: 0000-0001-6474-8112
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About
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Research Areas
  • Effects and risks of endocrine disrupting chemicals
  • Circadian rhythm and melatonin
  • Retinoids in leukemia and cellular processes
  • Synthesis and Biological Evaluation
  • Birth, Development, and Health
  • Adipose Tissue and Metabolism
  • Pesticide and Herbicide Environmental Studies
  • RNA regulation and disease
  • Photoreceptor and optogenetics research
  • Biochemical effects in animals
  • Diet and metabolism studies
  • Neuroscience and Neuropharmacology Research
  • Substance Abuse Treatment and Outcomes
  • Allelopathy and phytotoxic interactions
  • Cannabis and Cannabinoid Research
  • Toxic Organic Pollutants Impact
  • Prenatal Substance Exposure Effects
  • Smoking Behavior and Cessation

National University of Rosario
2006-2023

The purpose of this study was to determine whether 2,4-dichlorophenoxyacetic acid (2,4-D), which is an herbicide used control the growth broadleaf weeds, had a direct or indirect (mediated by undernutrition) hypomyelinating effect. We also proposed analyze effect 2,4-D on undernourished (UN) pups. Four experimental rat groups were used: well-nourished (WN) pups, litters with eight offsprings; UN fourteen WN pups whose mother received 70 mg/kg/day from postnatal day (PND) 9 21 (WN70 pups);...

10.1093/toxsci/kfn085 article EN Toxicological Sciences 2008-05-05

The herbicide 2,4-dichlorophenoxyacetic acid (2,4-D) is used on a wide variety of terrestrial and aquatic broadleaf weeds. 2,4-D has been shown to produce range adverse effects animal human health. aim the current study was evaluate pre- postnatal exposure rat ventral prostate (VP). Pregnant rats were exposed daily oral doses 70 mg/kg/day from 16 days gestation up 23 after delivery. Then, treated groups (n = 8) fed with added diet until sacrificed by decapitation day (PND) 45, 60, or 90....

10.3109/01480545.2015.1130718 article EN Drug and Chemical Toxicology 2016-01-12

Dopamine-β-hydroxylase (DβH), the enzyme that synthesizes noradrenaline from dopamine, was studied in locus coeruleus (LC) of neonate rats exposed to 2,4-dichlorophenoxyacetic acid (2,4-D) through lactation for 14 days (from PND 9 22). Pups (22 old) were anesthetized and fixed by transcardiac perfusion. Control treated serial sections brain stem—which correspond with LC according Paxinos Watson atlas—were simultaneously processed an immunohistochemistry method DβH detection. Using image...

10.1080/01480540600838058 article EN Drug and Chemical Toxicology 2006-01-01

Objectives Psychoactive substance (PS) use is a public health problem that affects society in general and particularly adolescents. Therefore, knowing adolescents' levels patterns of PSs essential for developing policies.Methods During 2016, 2018, 2019, total 1121 students (from Rosario-Argentina) were surveyed to evaluate their alcohol, energy drinks, tobacco, marijuana, among others.Results The results showed decrease the age onset as well risk perception PS use, especially 2018 2019....

10.1080/14659891.2023.2231545 article EN Journal of Substance Use 2023-07-05
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