A5018919150- Sperm and Testicular Function
- Chemotherapy-induced organ toxicity mitigation
- Natural Antidiabetic Agents Studies
- Drug-Induced Hepatotoxicity and Protection
- Moringa oleifera research and applications
- Ginger and Zingiberaceae research
- Selenium in Biological Systems
- Garlic and Onion Studies
- Anatomy and Medical Technology
- Fatty Acid Research and Health
- Dental Research and COVID-19
- Effects and risks of endocrine disrupting chemicals
- Coconut Research and Applications
- Nigella sativa pharmacological applications
- Pregnancy and Medication Impact
- Testicular diseases and treatments
- Carcinogens and Genotoxicity Assessment
- Ethnobotanical and Medicinal Plants Studies
- Melamine detection and toxicity
- Heavy Metal Exposure and Toxicity
- Bee Products Chemical Analysis
- Curcumin's Biomedical Applications
- Pressure Ulcer Prevention and Management
- Effects of Vibration on Health
- Phytochemistry and Bioactivity Studies
Benue State University
2022-2024
Bowen University
2019-2020
Alex Ekwueme Federal University, Ndufu-Alike
2019-2020
Funai Electric (Japan)
2020
Ebonyi State University
2014-2020
Afe Babalola University
2019-2020
University of Nigeria
2016
Lagos State University
2013
Benign Prostatic hyperplasia (BPH) is a common androgen associated urologic surgical disorder among the middle-aged and elderly. Certain phytotherapeutic agents have been discovered to halt its progression improve symptoms without causing toxic effect on body system. This study evaluated effects of three different doses (low, moderate high) Cymbopogon citratus aqueous extract (CCAE) testosterone induced-BPH in adult Wistar rats. Thirty-six (36) rats aged 10-12 weeks, weighing 100-120g were...
Background: The growing presence of synthetic chemicals in the environment has caused serious concerns about their impact on hormonal balance humans and animals. Many these substances, believed to disrupt endocrine system, have been linked reproductive problems worldwide. This includes rising infertility rates, particularly due negative effects health function testes. Objective: study was aimed at investigating scavenging potentials quercetin against melamine disruptive ability testes animal...
5-Fluorouracil (5-FU) is a strong anticancer agent commonly used for the treatment of various malignancies. However, its clinical utility countered by non-targeted nephrotoxicity and hepatotoxicity which sometimes unbearable cancer patients. Accumulating evidence has implicated oxidative stress pro-inflammation in 5-FU toxicity. The study explored whether Moringa oleifera seed oil (MOO) could protect against 5-FU-induced mechanism action Wistar rats. Rats were subjected to prophylactic oral...
Vernonia amygdalina (bitter-leaf) is native to West Africa but occurs mostly in its cultivated form various parts of central and southern Nigeria.It a dark-green leafy vegetable commonly used cooking as folkloric medicine for the management several diseases Nigeria.In present study, effects varying doses ethanolic leaf extract on rat testis histo-morphometry were investigated.Forty male wistar rats divided into groups four.Group A, control was given 10 ml/kg/day/oral distilled water while...
The utilization of herbal medicine in Nigeria is deeply embedded the nation’s cultural heritage and healthcare traditions, representing a unique fusion indigenous wisdom, diverse ethnic practices, abundant natural resources found across country’s varied landscapes. This comprehensive exploration delves into multifaceted dimensions Nigeria, including its historical, cultural, economic, aspects. It highlights rich knowledge medicinal plants passed down through generations, significance...
In this study, we assessed the protective potential of Vernonia amygdalina methanolic extract on aluminum chloride- induced neurotoxicity damage in Wistar rats. Forty Adult female rats weighing (109 ± 16 g) were randomly divided into four (4) groups (A-D, 10 respectively). Group A served as normal control (treated with 5 mL/kg saline) for 28 days, B received 0.43 Aluminum chloride (AlCL3) via oropharyngeal cannula 14 days and 1.31 mL after AlCL3 treatment 14days, C (VA) VA D only days. The...
Various commonly-used products have been reported to contain chemicals that could disrupt estrogen and testosterone hormone. As trade secrets, these are generally listed as fragrance mask individual identity. In this study, the reproductive implications of two commonly used perfumes (designated F1 F2) in Nigeria were carried out. Sixty adult male wistar rats (12-13 weeks old) randomly divided into four groups (A-F) ten each. Group A B exposed 5 mL kg-1 b.wt. normal saline for 56 days 112...
Background: Spermatogenesis is a complex series of differentiation process that can be interfered by toxic chemicals, heavy metals, heat, radiation, deficiencies hormones and immunodeficiency.Materials Methods: Fifteen male Wistar rats (10-12 weeks old) weighing 164-279 g were divided into three groups four each.The in group A served as the control treated with 2.5 mL kgG 1 b.wt., daily, B C given single dose 5 7 mg cadmium chloride solution intraperitoneally.The protocol lasted for 8...
Research studies that holistically investigated the effect of administration Virgin Coconut Oil (VCO) on diabetic humans or animals are limited in literature.To investigate VCO lipid profile, markers hepatic and renal dysfunction, antioxidant activities alloxan induced rats.Twenty-four male albino rats were used, they divided into four groups six each. Group 1 (Normal Control, NC) received distilled water (1 mL/kg); 2 (VCO Control) (5 3 (Diabetic DC) 4 (Test Group, TG) 5 ml/kg VCO.There no...
Aim: It is highly intricate to categorize a solitary or prevailing factor for pathophysiology of varicocele. Herein, the basis free radicals in pathogenesis varicocele was assessed.
Context: The study aims to evaluate the modulatory effect of an aqueous extract Moringa olifera on lead-mediated endometriosis in Wistar rats. Settings and Design: Twenty-five female rats were used for study. divided into five groups, each containing rats, treated daily fourteen days. Group I (Control) was administered 5ml/Kg distilled water per oral (PO), II given 50mg/Kg Lead PO, III 100mg/Kg (AMOE), IV received plus 200mg/Kg AMOE while V 50mg 300mg PO. Results: At end experiment, there...
Abstract Understanding the fundamental role anatomy education plays in medical training and taking into consideration nascence of online Nigeria, this study evaluated perceptions allied‐health students toward both during COVID‐19 lockdown Nigeria for future. For study, Google Form questionnaires were distributed via different social academic platforms to between September 28 December 17, 2020. A total 954 participated 947 valid responses recorded. The results showed that 77.6% had reported...
Cyclophosphamide (CYP) is a widely used anticancer drug that can also induce testicular toxicity, hence male factor infertility. This adverse effect of CYP be ameliorated by the antioxidant garlic oil. research work investigated effects Garlic oil (GO) on CYP-induced toxicity in Adult Male Wistar rats. Thirty-six adult rats were divided into 12 groups, each containing three (3) Groups 1 and 2 treated for 21 28 days respectively using 2mg/kg/BW Normal saline. 3 4 90mg/kg/day GO. 5 6 28days...
Melamine, a nitrogen-rich organic compound commonly used in industrial applications, became infamous during the 2008 Chinese milk scandal due to its association with renal damage and systemic toxicity. Its potential use as food additive raises concerns about safety, particularly regarding reproductive health. This review examines melamine’s impact on testicular health, focusing mechanisms of toxicity, exposure biomarkers, public health implications. A comprehensive literature experimental...