A5084334487- Glioma Diagnosis and Treatment
- Cancer Genomics and Diagnostics
- Genetic factors in colorectal cancer
Sorbonne Université
2023
Assistance Publique – Hôpitaux de Paris
2023
Vinh University
2023
PURPOSE The Lynch syndrome (LS)-glioma association is poorly documented. As for mismatch repair deficiency (MMRd) in glioma, a hallmark of LS-associated tumors, there are only limited data available. We determined MMRd and LS prevalence large series unselected gliomas, explored the associated characteristics. Both have major implications terms treatment, screening, prevention. METHODS Somatic next-generation sequencing was performed on 1,225 treatment-naive adult gliomas referred between...