A5061849703- Exercise and Physiological Responses
- Muscle metabolism and nutrition
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Pediatric health and respiratory diseases
- High Altitude and Hypoxia
- Nutrition and Health in Aging
- Long-Term Effects of COVID-19
- Cancer, Hypoxia, and Metabolism
- Herbal Medicine Research Studies
- Immune Response and Inflammation
- Body Composition Measurement Techniques
- Injury Epidemiology and Prevention
- Cancer, Stress, Anesthesia, and Immune Response
- Inflammatory mediators and NSAID effects
- Diabetes and associated disorders
- Immune Cell Function and Interaction
- COVID-19 and Mental Health
- Chemokine receptors and signaling
- Adipose Tissue and Metabolism
- Diet and metabolism studies
- Cardiovascular and Diving-Related Complications
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Physical Activity and Health
Universidade Federal de São Paulo
2019-2023
Background. Although Lactobacillus casei Shirota (LcS) can benefit the immune status, effects of LcS in immune/inflammatory responses marathon runners has never been evaluated. Therefore, here we evaluated effect daily ingestion fermented milk containing or not systemic and upper airway before after a marathon. Methods. Forty-two male ingested 40 billion LcS/day (LcS group, n = 20) placebo (unfermented milk, 22) during 30 days pre-marathon. Immune/inflammatory parameters nasal mucosa serum,...
Inflammaging is a phenomenon that has been associated with the development and progression of sarcopenia frailty syndrome. According to literature, on one side, increase in body fat systemic pro-inflammatory status, which consequently favors inflammaging, other regular practice physical exercise can mitigate this scenario. Therefore, here, we aimed evaluate association between inflammaging factors, both functional, group physically active older women.Seventy women (mean age 72.66 ± 6.17...
Although regular combined aerobic-resistance exercises can ameliorate the inflammatory status and redox balance in elderly population, it is unclear whether protein or specific amino acid supplementation could improve such benefits. Therefore, we aimed to evaluate indexes through of saliva 34 subject nonpractitioners (NP group, 73.3 ± 6.6 years) 49 practitioners a combined-exercise training moderate intensity (CET 71.9 5.8 before (pre) after (post) 30 days with L-glutamine (Gln) placebo...
Background: Since aging affects the immune responses against vaccination, present study evaluated effects of L-glutamine (Gln) supplementation in humoral and cellular elderly subjects, practitioners or not, physical exercise training. Methods: Eighty-four people (aged 72.6 ± 6.1), non-practitioners (NP, n = 31), combined-exercise training (CET, 53) were submitted to Influenza virus vaccination supplemented with Gln (0.3 g/kg weight + 10 g maltodextrin, groups: NP-Gln (n 14), CET-Gln 26)),...
Background: Although glutamine is able to improve the immune response, its action in upper airway immunity against influenza virus vaccine remains unclear. Therefore, we aimed evaluate L-glutamine supplementation effect on mucosal immune/inflammatory response of elderly subjects vaccinated virus. Methods: Saliva sampling from 83 physically active volunteers were collected pre- and 30 days after vaccination with (Gln, n = 42) or placebo (PL, 41). Results: Gln group showed higher salivary...
Although it has been previously demonstrated that acute inflammation can promote the tumor growth of a sub-tumorigenic dose melanoma cells through 5-lipoxygenase inflammatory pathway and its product leukotriene B4, also peritumoral treatment with eicosapentaenoic acid product, B5, reduces development, effect by gavage omega-3 omega-6 in microenvironment favorable to associated never studied. C57BL/6 mice were coinjected 1 × 106 apoptotic plus 103 viable into subcutaneous tissue treated...
Background: Because the consequences of lifestyle changes in older adults associated with social isolation imposed response to COVID-19 pandemic are not fully understood, here, we investigated effects one year by on metabolic parameters and functional physical capacity women who regularly practiced exercises before pandemic. Methods: Systemic lipid protein profiles, estimated creatinine clearance (ECC), (FPC) were assessed (January-February 2020) 12 months after 30 (mean age 73.77 ± 6.22)...
Background: In this study, we aimed to investigate the specific-antibody response COVID-19 vaccination and immunophenotyping of T cells in older adults who were engaged or not an exercise training program before pandemic. Methods: Ninety-three aged individuals (aged between 60 85 years) separated into 3 groups: practitioners physical vaccinated with CoronaVac (PE-Co, n = 46), ChadOx-1 (PE-Ch, 23), non-practitioners (NPE-Ch, 24). Blood samples collected (pre) 30 days after second vaccine...
Background: Firefighters are often exposed to high temperatures and by-products of combustion, which can compromise their health. We aimed evaluate the effect fire exposure in simulators on airways firefighters at different time-points. Methodology: Thirty-seven male were evaluated three phases: pre-exposure, end first week, 4 weeks after. Pulmonary function by spirometry, nasal mucociliary clearance; peripheral oxygen saturation, inflammatory markers lavage CC16 sputum, obstruction, quality...
OBJECTIVE: To elucidate the effect of oral L-glutamine (Gln) supplementation, associated or not with regular practice combined-exercise training (CET), on glycemic and lipid profile systemic inflammatory status in elderly subjects. METHODS: 84 subjects, non-practitioners (NP, n=31) practitioners CET (n=53), were supplemented Gln [0.3g/kg weight plus 10g maltodextrin, groups: NP-Gln (n=14), CET-Gln (n=26)], placebo [10g NP-PL (n=17), CET-PL (n=27)]. Anthropometric physical data assessed....
L-glutamine (LG) supplementation boost the immune system and benefit elderly, who present immunosenescence. However, no study has evaluated its effects on humoral response of upper airways elderly. Thus, this LG in elderly sedentary (Sed) physically active (CET=combined-exercise training: aerobic+resistance exercise), supplemented or not with LG, pulmonary function levels IL-6, IL-10 IL-6/IL-10 ratio nasal lavage fluid (NLF) saliva, as biomarkers airways. Four experimental groups were...
Introdução: A glutamina tem mostrado ser capaz de melhorar imunidade. Contudo, sua ação na resposta imune das vias aéreas superiores em idosos necessita esclarecimentos. Objetivo: Deste modo, nosso objetivo foi avaliar o efeito da suplementação L-glutamina inflamatória presente mucosa vacinados contra vírus Influenza. Material e métodos: Foram coletas amostras saliva 83 fisicamente ativos, dois momentos, antes (pré) após 30 dias (pós) a vacinação para Influenza também com (Gln, n=42) ou...