A5016191109- Hearing Loss and Rehabilitation
- Cardiac Health and Mental Health
- Intensive Care Unit Cognitive Disorders
- Obesity, Physical Activity, Diet
- Obesity and Health Practices
- Blood Pressure and Hypertension Studies
- Hearing, Cochlea, Tinnitus, Genetics
- Eating Disorders and Behaviors
- Cardiovascular Health and Risk Factors
- Health Policy Implementation Science
- Mental Health Treatment and Access
- Hearing Impairment and Communication
- Cardiac, Anesthesia and Surgical Outcomes
- Noise Effects and Management
- Birth, Development, and Health
- Anesthesia and Neurotoxicity Research
- Schizophrenia research and treatment
- Anesthesia and Sedative Agents
- Organ Donation and Transplantation
- Mobile Health and mHealth Applications
- Chronic Disease Management Strategies
- Heart Rate Variability and Autonomic Control
- Gestational Diabetes Research and Management
- Diet and metabolism studies
- Primary Care and Health Outcomes
Johns Hopkins Medicine
2016-2025
Johns Hopkins University
2016-2025
Duke University
2023
Cancer Research And Biostatistics
2022
Welch Foundation
2003-2021
RELX Group (Netherlands)
2021
National Heart Lung and Blood Institute
2021
National Institute on Aging
2021
Johns Hopkins Hospital
2021
Weatherford College
2021
The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders,...
The American Heart Association, in conjunction with the National Institutes of Health, annually reports most up-to-date statistics related to heart disease, stroke, and cardiovascular risk factors, including core health behaviors (smoking, physical activity, diet, weight) factors (cholesterol, blood pressure, glucose control) that contribute health. Statistical Update presents latest data on a range major clinical circulatory disease conditions (including congenital rhythm disorders,...
Obesity and its cardiovascular complications are extremely common medical problems, but evidence on how to accomplish weight loss in clinical practice is sparse.
Knee and hip injuries have been linked with osteoarthritis in cross-sectional case-control studies, but few prospective studies examined the relation between young adults risk for later osteoarthritis.To prospectively examine joint injury incident knee osteoarthritis.Prospective cohort study.Johns Hopkins Precursors Study.1321 former medical students.Injury status at entry was recorded when mean age of participants 22 years. Injury during follow-up were determined by using self-administered...
Background. Ethnic minority patients are less likely than white to receive guideline-concordant care for depression. It is uncertain whether racial and ethnic differences exist in patient beliefs, attitudes, preferences treatment. Methods. A telephone survey was conducted of 829 adult (659 non-Hispanic whites, 97 African Americans, 73 Hispanics) recruited from primary offices across the United States who reported 1 week or more depressed mood loss interest within past month met criteria...
<h3>Background</h3> Several studies have found that depression is an independent predictor of poor outcome after the onset clinical coronary artery disease. There are few data concerning as a risk factor for development <h3>Objective</h3> To determine if incident <h3>Patients and Methods</h3> The Johns Hopkins Precursors Study prospective, observational study 1190 male medical students who were enrolled between 1948 1964 continued to be followed up. In school through follow-up period,...
Most children with hearing loss who receive cochlear implants (CI) learn spoken language, and parents must choose early on whether to use sign language accompany speech at home. We address parents' of before after CI positively influences auditory-only recognition, intelligibility, reading outcomes.Three groups CIs from a nationwide database differed in the duration exposure provided their homes were compared progress through elementary grades. The did not differ demographic, auditory, or...
Background— The obesity-hypertension link over the life course has not been well characterized, although prevalence of obesity and hypertension is increasing in United States. Methods Results— We studied association body mass index (BMI) young adulthood, into middle age, through late with risk developing 1132 white men Johns Hopkins Precursors Study, a prospective cohort study. Over median follow-up period 46 years, 508 developed hypertension. Obesity (BMI ≥30 kg/m 2 ) adulthood was strongly...
PURPOSE: Obesity in middle age is associated with an increased risk of osteoarthritis the knees later life. We sought to determine whether body mass index young men was a factor for subsequent development knee and hip.SUBJECTS AND METHODS: Body assessed 1,180 male medical students at 23 ± 2 (mean SD) years several times during follow-up. The incidence hip ascertained by self-report corroborated information on symptoms radiographic findings.RESULTS: During median follow-up 36 years, 62...
Hypertension is a leading cause of stroke, heart disease, and kidney failure. The genetic basis blood pressure variation largely unknown but likely to involve genes that influence renal salt handling arterial vessel tone. Here we argue susceptibility hypertension ancestral differential due exposure selection pressures during the out-of-Africa expansion. most important was climate, which produced latitudinal cline in heat adaptation and, therefore, susceptibility. Consistent with this...
Background— Although trials of lifestyle interventions generally focus on cardiovascular disease risk factors rather than hard clinical outcomes, 10-year coronary heart (CHD) can be estimated from the Framingham equations. Our objectives were to study effect 2 multicomponent CHD relative advice alone and evaluate whether differences observed in effects among subgroups defined by baseline variables. Methods Results— A total 810 healthy adults with untreated prehypertension or stage I...
OBJECTIVE—The aim of this study was to test the hypothesis that diabetes is independently associated with reduced lung function, both cross-sectionally and longitudinally. RESEARCH DESIGN AND METHODS—We conducted cross-sectional prospective analyses status function decline using baseline 3-year follow-up data on 1,100 diabetic 10,162 nondiabetic middle-aged adults from Atherosclerosis Risk in Communities (ARIC) Study. Forced vital capacity (FVC) forced expiratory volume 1 s (FEV1) were...
Background: Depression is undertreated in primary care settings. Little research investigates the impact of patient involvement decisions on guideline-concordant treatment and depression outcomes. Objective: The objective this study was to determine whether decision-making associated with improvement symptoms. Design: Prospective cohort study. Setting: Multisite, nationwide randomized clinical trial quality strategies for care. Subjects: Primary patients current symptoms probable depressive...
This study examined specific spoken language abilities of 160 children with severe-to-profound sensorineural hearing loss followed prospectively 4, 5, or 6 years after cochlear implantation.Ninety-eight received implants before 2.5 years, and 62 between 5 age.Language was assessed using four subtests the Comprehensive Assessment Spoken Language (CASL). Standard scores were evaluated by contrasting age implantation follow-up test time.Children implanted under achieved higher standard than...
Although African American adults bear a disproportionate burden from diabetes mellitus (DM), few randomized controlled trials have tested culturally appropriate interventions to improve DM care.We randomly assigned 542 Americans with type 2 enrolled in an urban managed care organization either intensive or minimal intervention group. The group consisted of all components the plus individualized, tailored provided by nurse case manager (NCM) and community health worker (CHW), using...
<h3>Objective</h3> An aging American population carries a high prevalence of profound sensorineural hearing loss. We examined the performance multichannel cochlear implant recipients in large database adult subjects. <h3>Design</h3> Nonconcurrent prospective study national cohort with multivariate regression analysis preoperative and postoperative variables recipients. applied models prediction established previous studies to observed results. <h3>Setting</h3> Referral centers active...
<h3>Importance</h3> Postoperative delirium is the most common complication following major surgery in older patients. Intraoperative sedation levels are a possible modifiable risk factor for postoperative delirium. <h3>Objective</h3> To determine whether limiting during spinal anesthesia reduces incident overall. <h3>Design, Setting, and Participants</h3> This double-blind randomized clinical trial (A Strategy to Reduce Incidence of Delirum Elderly Patients [STRIDE]) was conducted from...
<h3>Importance</h3> Persons with serious mental illness have a cardiovascular disease mortality rate more than twice that of the overall population. Meaningful risk reduction requires targeted efforts in this population, who often psychiatric symptoms and cognitive impairment. <h3>Objective</h3> To determine effectiveness an 18-month multifaceted intervention incorporating behavioral counseling, care coordination, management for adults illness. <h3>Design, Setting, Participants</h3> This...
<h3>Background</h3> Anger can trigger myocardial ischemia and may be an independent risk factor for coronary heart disease, but its effect on early compared with late onset of disease is unclear. <h3>Methods</h3> We performed a prospective study 1055 men followed up 32 to 48 years examine the premature total cardiovascular (CVD) associated anger responses stress during adult life. Highest level was defined as self-report all 3 possible reactions (expressed or concealed anger, gripe sessions,...
Whether the increase in blood pressure with coffee drinking seen clinical trials persists over time and translates into an increased incidence of hypertension is not known.We assessed intake a cohort 1017 white male former medical students (mean age, 26 years) graduating classes from 1948 to 1964 up 11 times median follow-up 33 years. Blood were determined annually by self-report, demonstrated be accurate this cohort.Consumption 1 cup day raised systolic 0.19 mm Hg (95% confidence interval,...