- Action Observation and Synchronization
- Virtual Reality Applications and Impacts
- Sport Psychology and Performance
- Glycosylation and Glycoproteins Research
- Cytomegalovirus and herpesvirus research
- Hepatitis C virus research
- SARS-CoV-2 and COVID-19 Research
- Neonatal and Maternal Infections
- Gout, Hyperuricemia, Uric Acid
- Cell death mechanisms and regulation
- Long-Term Effects of COVID-19
- EEG and Brain-Computer Interfaces
- Computational Drug Discovery Methods
- Analytical Chemistry and Chromatography
- Parvovirus B19 Infection Studies
- vaccines and immunoinformatics approaches
- interferon and immune responses
- Tactile and Sensory Interactions
- Natural product bioactivities and synthesis
- HIV Research and Treatment
- Herpesvirus Infections and Treatments
- Pharmacological Effects of Natural Compounds
- HIV/AIDS drug development and treatment
- Growth Hormone and Insulin-like Growth Factors
- Immune Response and Inflammation
Southern Medical University
2024-2025
Beihang University
2024
Ministry of Civil Affairs
2024
University Health System
2012
Michigan Medicine
2012
Medical Research Council
2006-2009
MRC Human Immunology Unit
2006-2009
Peking University First Hospital
2008
Peking University
2008
John Radcliffe Hospital
2006
Abstract The authors have previously shown that acute lung injury (ALI) produces a wide spectrum of pathological processes in patients who die severe respiratory syndrome (SARS) and the SARS coronavirus (SARS‐CoV) nucleoprotein is detectable lungs, other organs tissues, these patients. In present study, immunohistochemistry (IHC) situ hybridization (ISH) assays were used to analyse expression angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV spike (S) protein, some pro‐inflammatory cytokines...
The causative agent of severe acute respiratory syndrome (SARS) is a previously unidentified coronavirus, SARS-CoV. RNA-dependent RNA polymerase (RdRp) SARS-CoV plays pivotal role in viral replication and potential target for anti-SARS therapy. There lack structural or biochemical data on any coronavirus polymerase. To provide insights into the structure function RdRp, we have located its conserved motifs that are shared by all RdRps, built three-dimensional model catalytic domain. permits...
A molecularly imprinted polymer (MIP) was synthesized for the selective extraction of oleanolic acid (OA), employing OA as template molecule, acrylamide functional monomer, ethylene glycol dimethacrylate cross-linking agent, azobisisobutyronitrile initiator, and chloroform porogenic solvent. The characterization obtained MIPs evaluated by scanning electron microscopy, Fourier transform infrared spectroscopy, Brunauer-Emmett-Teller (BET) analysis X-ray photoelectron spectroscopy. reached...
Virtual reality (VR)-based rehabilitation training holds great potential for post-stroke motor recovery. Existing VR-based imagery (MI) paradigms mostly focus on the first-person perspective, and benefit of third-person perspective (3PP) remains to be further exploited. The 3PP is advantageous movements involving back or those with a large range because its field coverage. Some are easier imagine from 3PP. However, efficiency may unsatisfactory, which attributed difficulty encountered when...
Please cite this paper as: Berger M, Xu X, Williams J, Van de Ven C, Mozurkewich E. Early hospital discharge of infants born to group B streptococci‐positive mothers: a decision analysis. BJOG 2012;119:439–448. Objective To compare the cost‐effectiveness an additional 24‐hour inpatient observation for asymptomatic term neonates streptococcus (GBS) ‐colonised mothers with adequate intrapartum antibiotic prophylaxis (IAP) after initial in‐hospital observation. Design Cost‐effectiveness...
Virtual reality (VR)-guided motor imagery (MI) is a widely used approach for rehabilitation, especially patients with severe impairments. Most approaches provide visual guidance from the first-person perspective (1PP). MI training third-person (3PP) remains largely unexplored. We argue that 3PP has its own advantages and can supplement 1PP MI. For some movements beyond view of 1PP, such as shoulder shrugging other axial movements, are suitable performed under 3PP. However, efficiency...
Background The accurate identification of HIV-1-specific T cell responses is important for determining the relationship between immune and viral control. Overlapping peptides were synthesized to span gag nef core 'mosaic' proteins. Mosaic proteins assembled from fragments natural sequence using an optimized computational biology method (W. Fischer et al., Nature Medicine, 2007). These resemble designed maximize coverage potential epitopes. Whilst recent studies have shown that mosaic are...
Background High rates of mutation in HIV infected individual allow the virus to adapt rapidly vivo selective forces such as anti-retroviral therapy (ART) and host immune pressure. This provides an opportunity determine relative contribution different components response HIV-1 infection driving viral diversity, which may also facilitate assessment their role controlling replication. It is accepted that HIV-1-specific cytotoxic T-lymphocytes (CTL) drive selection variants can escape T-cell...