Fang Pu

ORCID: 0000-0002-1467-006X
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About
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Research Areas
  • Diabetic Foot Ulcer Assessment and Management
  • Functional Brain Connectivity Studies
  • Lower Extremity Biomechanics and Pathologies
  • Cardiovascular Health and Disease Prevention
  • Pressure Ulcer Prevention and Management
  • Advanced Neuroimaging Techniques and Applications
  • Stroke Rehabilitation and Recovery
  • Diagnosis and Treatment of Venous Diseases
  • Virtual Reality Applications and Impacts
  • Coronary Interventions and Diagnostics
  • Balance, Gait, and Falls Prevention
  • Cerebrovascular and Carotid Artery Diseases
  • Muscle activation and electromyography studies
  • Action Observation and Synchronization
  • Complex Systems and Time Series Analysis
  • Acute Ischemic Stroke Management
  • Evaluation Methods in Various Fields
  • Access Control and Trust
  • Cerebral Palsy and Movement Disorders
  • Visual perception and processing mechanisms
  • Advanced Decision-Making Techniques
  • Context-Aware Activity Recognition Systems
  • Fire dynamics and safety research
  • Dementia and Cognitive Impairment Research
  • Evaluation and Optimization Models

Ministry of Civil Affairs
2016-2024

Beihang University
2014-2024

Nanchang University
2021-2024

First Affiliated Hospital of Jiangxi Medical College
2024

Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2024

State Key Laboratory of Virtual Reality Technology and Systems
2024

Hefei University of Technology
2021-2023

First Affiliated Hospital of Anhui Medical University
2023

Anhui Medical University
2023

Donghua University
2007-2022

It has been proposed that a mass transfer phenomenon called concentration polarization of low-density lipoproteins (LDLs) may occur in the arterial system and is likely involved localization atherogenesis. To test hypothesis LDL be suppressed by helical flow pattern human aorta, hence sparing ascending aorta from atherosclerosis, effects aortic torsion, branching, curvature, taper on blood transport lumen were simulated numerically under steady-state conditions using four models constructed...

10.1152/ajpheart.00266.2009 article EN AJP Heart and Circulatory Physiology 2009-05-09

Rationale: Hyperhomocysteinemia (HHcy) accelerates atherosclerosis and increases inflammatory monocytes (MC) in peripheral tissues. However, its causative role is not well established effect on vascular inflammation has been studied. The underlying mechanism unknown. Objective: This study examined the of HHcy atherogenesis MC differentiation. Methods Results: We generated a novel hyperlipidemia mouse model, which cystathionine β-synthase (CBS) low-density lipoprotein receptor (LDLr) genes...

10.1161/circresaha.112.269472 article EN Circulation Research 2012-05-25

Microsoft Kinect uses a built-in RGB-D sensor and the skeleton tracking algorithm to capture 3-D movements of human body. It also has potential for assessing postural stability, which is fundamental most motor activities. The aim this paper was investigate whether standing balance can be evaluated reliably validly by low-cost device. Nine healthy subjects were required maintain during three positions (double limb stance with feet apart, double together single stance). center mass (COM)...

10.1109/jsen.2013.2296509 article EN IEEE Sensors Journal 2014-01-31

<b>BACKGROUND AND PURPOSE:</b> Alzheimer disease (AD) is a neurodegenerative characterized by progressive dementia. The hippocampus particularly vulnerable to damage at the very earliest stages of AD. This article seeks evaluate critical AD-associated regional changes in using machine learning methods. <b>MATERIALS METHODS:</b> High-resolution MR images were acquired from 19 patients with AD and 20 age- sex-matched healthy control subjects. Regional bilateral hippocampi computational...

10.3174/ajnr.a0620 article EN cc-by American Journal of Neuroradiology 2007-08-01

Rationale: Patients with chronic kidney disease (CKD) develop hyperhomocysteinemia and have a higher cardiovascular mortality than those without by 10-fold. Objective: We investigated monocyte differentiation in human CKD (CVD). Methods Results: identified CD40 as CKD-related activation gene using CKD-monocyte -mRNA array analysis classified (CD40 + CD14 ) stronger inflammatory subset the intermediate (CD14 ++ CD16 subset. recruited 27 patients CVD/CKD 14 healthy subjects found that...

10.1161/circresaha.116.308750 article EN Circulation Research 2016-11-11

Previous studies have suggested that amnestic mild cognitive impairment (aMCI) is associated with changes in cortical morphological features, such as thickness, sulcal depth, surface area, gray matter volume, metric distortion, and mean curvature. These features been proven to specific neuropathological genetic underpinnings. However, most primarily focused on mass-univariate methods, were generally explored isolation. Here, we used a multivariate method characterize the complex subtle...

10.1523/jneurosci.4356-13.2014 article EN Journal of Neuroscience 2014-08-06

Previous neuroimaging studies have suggested that cerebral changes over normal aging are not simply characterized by regional alterations, but rather the reorganization of cortical connectivity patterns. The investigation structural covariance networks (SCNs) using voxel-based morphometry is an advanced approach to examining pattern in gray matter (GM) volumes among different regions human cortex. To date, how organization critical SCNs change during remains largely unknown. In this study,...

10.3389/fnhum.2013.00098 article EN cc-by Frontiers in Human Neuroscience 2013-01-01

Visual guided motor imagery (MI) is commonly used in stroke rehabilitation, eliciting event-related desynchronization (ERD) EEG. Previous studies found that immersion level and visuo-tactile stimulation could modulate ERD during visual MI, both of two factors also improve sense ownership (SOO) over target limb (or body). Additionally, the relationship was reported between performance MI SOO. This study aims to investigate whether affect through SOO virtual body patients. Nineteen patients...

10.1109/tnsre.2024.3364505 article EN cc-by IEEE Transactions on Neural Systems and Rehabilitation Engineering 2024-01-01

Virtual reality (VR)-based rehabilitation training holds great potential for post-stroke motor recovery. Existing VR-based imagery (MI) paradigms mostly focus on the first-person perspective, and benefit of third-person perspective (3PP) remains to be further exploited. The 3PP is advantageous movements involving back or those with a large range because its field coverage. Some are easier imagine from 3PP. However, efficiency may unsatisfactory, which attributed difficulty encountered when...

10.1109/tnsre.2024.3365587 article EN cc-by IEEE Transactions on Neural Systems and Rehabilitation Engineering 2024-01-01

Objective: Poor blood flow supply is an important pathological factor that leads to the development and deterioration of diabetic foot ulcers. This study aims investigate acute effects local vibration with varying intermittent durations on plantar skin (SBF) response in healthy subjects. Methods: Eleven patients (7 males, 4 females) 15 adults (6 9 participated this experiment accepted three tests. Local continuous (LCV) two levels (LIV1 LIV2) were randomly applied middle metatarsal head each...

10.3389/fbioe.2019.00310 article EN cc-by Frontiers in Bioengineering and Biotechnology 2019-11-05

Abstract Background Exercise, especially weight-bearing exercise (e.g. walking), may affect plantar tissue viability due to prolonged repetitive high vertical and shear pressure stimulus on the tissue, further induce development of diabetic foot ulcers (DFUs). This study aimed investigate effects different accumulated pressure-time integral (APTI) stimuli induced by walking skin blood flow (SBF) responses in people with diabetes mellitus (DM). Methods A repeated measures design was used this...

10.1186/s12891-021-04437-9 article EN cc-by BMC Musculoskeletal Disorders 2021-06-18

Most studies that attempt to clarify structural abnormalities related functional disconnection in patients with Alzheimer's disease (AD) have focused on exploring pathological changes cortical gray matter. However, white matter fibers connecting these cerebral areas may also be abnormal.To investigate the regional of volume AD compared healthy subjects.White whole-brain magnetic resonance images acquired from 19 and 20 subjects (control group) were observed using optimized voxel-based...

10.1080/02841850701627181 article EN Acta Radiologica 2008-01-22

Galvanic vestibular stimulation (GVS) can be used to study the body’s response stimuli. This aimed investigate whether postural responses GVS were different between pilots and general populace. Bilateral bipolar was applied with a constant-current profile 12 control subjects via two electrodes placed over mastoid processes. Both threshold center of pressure’s trajectory (COP’s trajectory) measured. Position variability COP during spontaneous body sway peak displacement GVS-induced calculated...

10.1155/2015/567690 article EN cc-by BioMed Research International 2015-01-01

Objective: People with diabetic peripheral neuropathy (DPN) are usually accompanied increased plantar pressure. Such high loading during daily activities may cause changes in the biomechanical properties of soft tissue, whose viability is critical to development foot ulcers. This study aimed investigate relationship between tissue hardness and pressure people without DPN, preliminarily explore influence patterns on hardness. Methods: The was conducted 14 DPN DPN. Shore durometer MatScan...

10.3389/fbioe.2022.836018 article EN cc-by Frontiers in Bioengineering and Biotechnology 2022-04-04
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