A5100441036- Coronary Interventions and Diagnostics
- Cardiovascular Health and Disease Prevention
- Esophageal Cancer Research and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Esophageal and GI Pathology
- Cervical and Thoracic Myelopathy
- Aortic aneurysm repair treatments
- Gastric Cancer Management and Outcomes
- Spine and Intervertebral Disc Pathology
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac Imaging and Diagnostics
- Tissue Engineering and Regenerative Medicine
- Heart Rate Variability and Autonomic Control
- Spinal Fractures and Fixation Techniques
- Nitric Oxide and Endothelin Effects
- Aortic Disease and Treatment Approaches
- Advanced MRI Techniques and Applications
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Cellular Mechanics and Interactions
- Electrospun Nanofibers in Biomedical Applications
- Tendon Structure and Treatment
- Blood properties and coagulation
- Hippo pathway signaling and YAP/TAZ
- Lung Cancer Diagnosis and Treatment
Beihang University
2016-2025
Henan Cancer Hospital
2020-2025
Zhengzhou University
2023-2025
Ministry of Industry and Information Technology
2025
Guangzhou University of Chinese Medicine
2021-2024
Peking University
2015-2024
Peking University Third Hospital
2015-2024
Zhongnan Hospital of Wuhan University
2024
Wuhan University
2024
Hua Medicine (China)
2024
Sensing technology has been widely investigated and utilized for gas detection. Due to the different applicability inherent limitations of sensing technologies, researchers have working on scenarios with enhanced sensor calibration. This paper reviews descriptions, evaluation, comparison recent developments in existing technologies. A classification technologies is given, based variation electrical other properties. Detailed introduction methods discussed through further according materials,...
It has been proposed that a mass transfer phenomenon called concentration polarization of low-density lipoproteins (LDLs) may occur in the arterial system and is likely involved localization atherogenesis. To test hypothesis LDL be suppressed by helical flow pattern human aorta, hence sparing ascending aorta from atherosclerosis, effects aortic torsion, branching, curvature, taper on blood transport lumen were simulated numerically under steady-state conditions using four models constructed...
Dynamic curved interfaces are fundamental and ubiquitous structures in biological systems. However, replicating the structure function associated with these for mechanobiology drug screening is challenging. Here, we develop a dynamic curvature-enabled microfluidic organ chip of two fluid–solid interfaces. One interface effectively integrates adjustable biomechanics, other controls release open microfluidics. The sensed by cells can modulate residual stress, stiffness, strain solid phase,...
The ability to pattern planar and freestanding 3D metallic architectures would enable numerous applications, including flexible electronics, displays, sensors, antennas. Low melting point metals, such as gallium, have recently drawn considerable attention especially in the fields of stretchable electronics devices owing its unique properties, excellent electrical conductivity fluidity. However, large surface tension, low viscosity, density pose great challenges printing gallium structures a...
Radiotherapy is a common treatment for patients with esophageal cancer. Esophageal fistula (perforation) serious complication in advanced It unclear how radio/chemotherapy post-fistula may affect survival malignant fistulae radiotherapy pre-fistula. We sought to evaluate and cancer In retrospective cohort study, we reviewed treatments 98 prior or without chemotherapy between 2010/6 2023/5 regional care centre Zhengzhou, China. The primary outcome was time (months) post-fistula. inverse of...
Functional microvasculature is essential for in vitro tissue constructs, ensuring efficient transport of oxygen, nutrients, and waste supporting vital paracrine signaling stability. Recent advancements both direct indirect 3D bioprinting offer promising solutions to construct complex vascular networks by allowing precise control over cell extracellular matrix placement. The process from shape printing function formation involves dynamic shift bioink mechanical properties, microenvironments,...
Nerves spread throughout human bone minerals and play an important role in regulating osteogenic homeostasis. However, whether the distributive nerves can sense of nerve outgrowth are still unclear. We hypothesized that a natural magnesium-containing mineral, whitlockite (WH), second most abundant mineral body, could simultaneously promote both neural activities. To verify hypothesis, WH hydroxyapatite (HAP) nanoparticles were synthesized, their characterization was completed by...
Intravenous immunoglobulin (IVIG) is the treatment of choice in Kawasaki disease (KD). IVIG used to prevent cardiovascular complications related KD. However, a proportion KD patients have persistent fever after and are defined as resistant.To develop risk scoring system based on genetic markers predict responsiveness patients, total 150 (126 responders 24 nonresponders) were recruited for this study. A genome-wide association analysis was performed compare 2 groups identified alleles...
To test the hypothesis that disturbed flow can impede transport of nitric oxide (NO) in artery and hence induce atherogenesis, we used a lumen–wall model an idealized arterial stenosis with NO produced at blood vessel–wall interface to study stenosis. Blood flows lumen through wall were simulated by Navier–Stokes equations Darcy's Law, respectively. Meanwhile, within modelled advection–diffusion reaction equations. Coupling fluid dynamics endothelium was achieved Kedem–Katchalsky The results...
Two mechanisms of shear stress and mass transport have been recognized to play an important role in the development localized atherosclerosis. However, their relationship roles atherogenesis are still obscure. It is necessary investigate quantitatively correlation among low-density lipoproteins (LDL) transport, haemodynamic parameters plaque thickness. We simulated blood flow LDL rabbit aorta using computational fluid dynamics evaluated thickness a high-fat-diet rabbit. The numerical results...
The vascular smooth muscle cells (VSMCs) are exposed to interstitial flow induced shear stress that may be sensed by the surface glycocalyx, a layer composed primarily of proteoglycans and glycoproteins, mediate cell contraction during myogenic response. We, therefore, attempted elucidate signal pathway glycocalyx mechanotransduction in regulated SMC contraction. Human umbilical vein SMCs (HUVSMCs) deprived serum for 3-4 days were step increase (0 20 dyn/cm2) parallel plate chamber,...
The aim of this study was to explore the application value shear wave elastography in healthy adults with knee meniscus.One hundred adult subjects who underwent health checkups at our hospital from December 2022 February 2023 were selected as research participants. Shear used evaluate periphery lateral and medial meniscus both knees. To assess mean differences Young's modulus values between male female groups, a one-way analysis variance (ANOVA) independent samples t-test conducted. In...
There is currently an urgent need to develop engineered scaffolds support new adipose tissue formation and facilitate long-term maintenance of function defect repair further generate prospective bioactive filler materials capable fulfilling surgical needs. Herein, regeneration methods were optimized decellularized (DAT) with good biocompatibility fabricated. Adipose-like tissues reconstructed using the DAT 3T3-L1 preadipocytes, which have certain differentiation potential, regenerative effects
Despite the crucial role of nitric oxide (NO) in homeostasis vasculature, little quantitative information exists concerning NO transport and distribution medium large-sized arteries where atherosclerosis aneurysm occur hemodynamics is complex. We hypothesized that local may govern affect arteries, hence playing an important localization vascular diseases. To substantiate this hypothesis, we presented a lumen/wall model human aorta based on its MRI images to simulate production, consumption...