A5101781001- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Electrospun Nanofibers in Biomedical Applications
- Machine Learning in Bioinformatics
- Coronary Interventions and Diagnostics
- Intracranial Aneurysms: Treatment and Complications
- Lung Cancer Treatments and Mutations
- Fractal and DNA sequence analysis
- RNA and protein synthesis mechanisms
- Histone Deacetylase Inhibitors Research
- Lung Cancer Research Studies
- Cancer-related molecular mechanisms research
- PARP inhibition in cancer therapy
- Cancer-related gene regulation
Second Military Medical University
2022-2024
Changhai Hospital
2024
Beihang University
2016
Bohai University
2010
Background:The single nucleotide polymorphism (SNP) of Gastrokine-1 (GKN1) is associated with lung cancer but its association prognosis not clear.Methods: Genomic DNA was extracted from the blood samples 888 patients cancer.The between GKN1 rs4254535 and prognostic analyzed by Kaplan-Meier (KM) method, Log-rank test, Cox proportional hazards model. Results:In females diagnosed late-stage cancer, CC genotype (CC vs TT, adjusted odds ratio [HR] = 0.57, 95% Confidence Interval [CI]: 0.33-0.99,P...
Background:GPC5 rs2352028 is associated with the risk of lung cancer, but its relationship cancer prognosis unclear. Materials & methods: The authors collected blood samples from 888 patients and used a Cox proportional hazards model to analyze association between GPC5 polymorphism rs2352028. Results:GPC5 C > T was better prognosis. Patients CT genotype had longer overall survival than those CC genotype. Additionally, older early-stage + TT lower death Conclusion:GPC5 may play protective...