A5101058250- Cardiac Imaging and Diagnostics
- Advanced MRI Techniques and Applications
- Advanced X-ray and CT Imaging
- Cardiovascular Function and Risk Factors
- Radiation Dose and Imaging
- Coronary Interventions and Diagnostics
- Aortic Disease and Treatment Approaches
- Cerebrovascular and Carotid Artery Diseases
- Cardiovascular Disease and Adiposity
- Aortic aneurysm repair treatments
- Cardiovascular Health and Disease Prevention
- Cardiomyopathy and Myosin Studies
- Cardiac Structural Anomalies and Repair
- Nanoparticle-Based Drug Delivery
- Medical Imaging Techniques and Applications
- Cardiac Valve Diseases and Treatments
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Acute Kidney Injury Research
- Ultrasound and Hyperthermia Applications
- ECG Monitoring and Analysis
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Issues in Pregnancy
- Anatomy and Medical Technology
- Atomic and Subatomic Physics Research
Beijing Anzhen Hospital
2011-2023
Capital Medical University
2013-2023
RELX Group (United States)
2020
London Borough of Camden
2020
Curtin University
2015-2018
First Affiliated Hospital of Kunming Medical University
2015
Capital University
2013-2015
Feminist Archive North
2015
Kunming Medical University
2015
Identification and Quantification of Coronary Atherosclerotic Plaques: A Comparison 64-MDCT Intravascular UltrasoundJunyan Sun1, Zhaoqi Zhang1, Biao Lu1, Wei Yu1, Ya Yang2, Yujie Zhou3, Yanhui Wang1 Zhanming Fan1Audio Available | Share
As nanotheranostics, Congo red/Rutin-MNPs combine the abilities of diagnosis and treatment Alzheimer's disease (AD). The biocompatible nanotheranostics system based on iron oxide magnetic nanoparticles, with ultrasmall size excellent properties, can specifically detect amyloid plaques by resonance imaging, realize targeted delivery AD therapeutic agents, achieve drug controlled release H2O2 response, prevent oxidative stress. a service to our authors readers, this journal provides supporting...
The controllable self-assembly of amphiphilic mixed polymers grafted gold nanoparitcles (AuNPs) leads to strong interparticle plasmonic coupling, which can be tuned the near-infrared (NIR) region for enhanced photothermal therapy (PTT).In this study, an improved thiolation method was adopted ATRP and ROP polymer obtain brushes PMEO 2 MA-SH PCL-SH.By anchoring PCL-SH onto 14 nm AuNPs, a smart hybrid building block obtained.Increasing PCL/PMEO MA chain ratio from 0.8:1, 2:1 3:1 7:1, structure...
Objective Current diagnostic assessment tools remain suboptimal in demonstrating complex morphology of congenital heart disease (CHD). This limitation has posed several challenges preoperative planning, communication medical practice, and education. study aims to investigate the dimensional accuracy clinical value 3D printed model CHD above three areas. Methods Using cardiac computed tomography angiography (CCTA) data, a patient-specific 20-month-old boy with double outlet right ventricle...
Abstract The purpose of this study was to find the circulating microRNAs (miRNAs) co-related with severity coronary artery calcification (CAC) and testify whether selected miRNAs could reflect obstructive disease in symptomatic patients. Patients chest pain moderated risk for (CAD) were characterized calcium score (CACS) from cardiac computed tomography (CT). We analyzed plasma miRNA levels clinical matched 11 CAC (CACS > 100) 6 non-CAC = 0) subjects by microarray profile. Microarray...
Reference values on atrial and ventricular strain from cardiovascular magnetic resonance (CMR) are essential in identifying patients with impaired function. However, reference have not been established for Chinese subjects. One hundred fifty healthy volunteers (75 Males/75 Females; 18-82 years) were recruited. All underwent CMR scans images acceptable further analysis. Subjects stratified by age: Group 1, 18-44 years; 2, 45-59 3, ≥60 years. Feature tracking of cine imaging was used to obtain...
The aim of this study was to investigate the use de-blooming algorithm in coronary CT angiography (CCTA) for optimal evaluation calcified plaques. Calcified plaques were simulated on a vessel phantom and cardiac motion phantom. Two convolution kernels, standard (STND) high-definition (HD STND), used imaging reconstruction. A dedicated processing. We found smaller bias towards measurement stenosis using (STND: 24.6% vs 15.0%, range 10.2% 39.0% 4.0% 25.9%; HD STND: 17.9% 11.0%, 8.9% 30.6% 0.5%...
Objective To assess the image quality of aorta obtained by dual-source computed tomography angiography (DSCTA), performed with high pitch, low tube voltage, and iodine concentration contrast medium (CM) images reconstructed using iterative reconstruction (IR). Methods One hundred patients randomly allocated to receive one two types CM underwent DSCTA electrocardiogram-triggered Flash protocol. In low-iodine group, 50 received containing 270 mg I/mL were scanned at voltage (100 kVp)....
Background: T1 mapping enables assessment of myocardial characteristics.As the most common type arrhythmia, atrial fibrillation (AF) is often accompanied by a variety cardiac pathologies, whereby irregular and usually rapid ventricle rate AF may cause inaccurate estimation due to mis-triggering inadequate magnetization recovery.We hypothesized that systolic with heart-rate-dependent (HRD) pulse sequence scheme overcome this issue.Methods: 30 patients 13 healthy volunteers were enrolled...
Currently unsatisfactory treatment of myocardial infarction (MI) is due to the unbridled inflammation and delayed diagnosis at early stage. To address these problems, firstly, phosphatidylserine (PS) was used modulate phenotypes macrophages (MΦ) resolve via binding PS receptors (PSR) on macrophage surface. Secondly, highly-sensitive magnetic iron oxide nanocubes (MIONs) were adopted realize visualization resonance imaging (MRI). However, major drawback for MIONs as contrast agents their...
Objective The aim of this study was to investigate the impact a motion-correction algorithm on diagnostic accuracy coronary computed tomography angiography (CCTA) within 1 heart beat in patients with high rate (HR) using 256-row detector CT. Method Sixty-four consecutive known or suspected artery disease (symptomatic) and HR 75 beats per minute greater (mean [SD] HR, 82.6 [7.3] minute) undergoing CCTA invasive 4 weeks were prospectively enrolled. Coronary performed CT (Revolution CT, GE...
The purpose of this study was to prospectively evaluate the effects mean heart rate and variability on image quality at coronary 64-MDCT angiography patients with atrial fibrillation determine efficacy in detection significant (> 50%) artery stenosis fibrillation.Sixty (37 women, 23 men; age, 58.7 years) underwent both conventional angiography. Heart calculated as SD from during scanning. Image (good, moderate, or poor) presence CT were evaluated by two radiologists blinded results...
The purpose of this study is to evaluate the hemodynamic characteristics true lumen (TL) and false (FL) in 16 patients with aortic dissection (AD) using 4D flow magnetic resonance imaging (MRI) thoracic abdominal computed tomography (CT) angiography. quantitative parameters that were measured TL FL included velocity flow. mean area regurgitant fraction significantly lesser at all four levels (p < 0.05); average through-plane velocity, peak magnitude, net flow, forward volume considerably...
To compare the diagnostic value of coronary CT angiography (CCTA) with use 2 image postprocessing methods (CCTA_S) and (CCTA_OS) original data (CCTA_O) for assessment heavily calcified plaques. Fifty patients (41 men, 9 women; mean age 61.9 years ± 9.1) suspected artery disease who underwent CCTA invasive (ICA) examinations were included in study. Image postprocessed "sharpen" smooth reconstruction algorithms comparison without undergoing any to determine effects on suppressing blooming...
Despite the crucial role of nitric oxide (NO) in homeostasis vasculature, little quantitative information exists concerning NO transport and distribution medium large-sized arteries where atherosclerosis aneurysm occur hemodynamics is complex. We hypothesized that local may govern affect arteries, hence playing an important localization vascular diseases. To substantiate this hypothesis, we presented a lumen/wall model human aorta based on its MRI images to simulate production, consumption...