Chengnan Li

ORCID: 0009-0000-0342-558X
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About
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Research Areas
  • Aortic Disease and Treatment Approaches
  • Aortic aneurysm repair treatments
  • Cardiac Valve Diseases and Treatments
  • Cardiac Structural Anomalies and Repair
  • Infectious Aortic and Vascular Conditions
  • Congenital Heart Disease Studies
  • Cardiovascular Issues in Pregnancy
  • Vasculitis and related conditions
  • Cardiac, Anesthesia and Surgical Outcomes
  • Radiomics and Machine Learning in Medical Imaging
  • Hip and Femur Fractures
  • Renal and Vascular Pathologies
  • Heavy Metals in Plants
  • Brain Metastases and Treatment
  • Coronary Artery Anomalies
  • Cardiac and Coronary Surgery Techniques
  • Nosocomial Infections in ICU
  • Intracranial Aneurysms: Treatment and Complications
  • E-commerce and Technology Innovations
  • Acute Myocardial Infarction Research
  • Vascular Anomalies and Treatments
  • Biomarkers in Disease Mechanisms
  • Insurance and Financial Risk Management
  • MicroRNA in disease regulation
  • Advanced Radiotherapy Techniques

Beijing Anzhen Hospital
2016-2025

Capital Medical University
2016-2025

Yanbian University Hospital
2012-2024

University of Wisconsin–Madison
2024

Lanzhou University
2021-2024

Beijing Institute of Water
2018-2021

Chongqing University of Posts and Telecommunications
2021

Xian Yang Central Hospital
2012

Chinese Academy of Medical Sciences & Peking Union Medical College
2012

The open anastomosis technique is a classic procedure for treating extended ascending aortic aneurysms, but hypothermic circulatory arrest unavoidable, which increases the risk of organ injury. arch-clamping (AAC) an alternative treatment. This study aimed to evaluate efficacy AAC in patients with aneurysms extending proximal arch. From January 2015 February 2022, 230 arch underwent surgical intervention. Based on type distal aorta surgery, were divided into group (n=117 cases) and (ODA)...

10.21037/jtd-24-1133 article EN Journal of Thoracic Disease 2025-01-01

Type A aortic dissection is a life-threatening condition requiring urgent surgery. However, clinical experience with type during twin pregnancy extremely limited. We report case of 32-year-old woman Marfan syndrome who was diagnosed at 37 weeks gestation boy-girl twins. The patient successfully underwent cesarean delivery followed by root replacement. Both the mother and twins were discharged without complications.

10.1093/icvts/ivaf039 article EN cc-by-nc Interdisciplinary CardioVascular and Thoracic Surgery 2025-03-05

Objective: To analyze the clinical outcome of corticosteroid and/or immunosuppressive treatment preoperatively in patients with Takayasu's arteritis. Patients and Methods: Forty-six arteritis who received cardiovascular surgery between January 2010 December 2015 Beijing Anzhen Hospital were enrolled this study. Their characteristics, preoperative drug therapy, surgical treatment, pathological examination results retrospectively analyzed for effect drugs on surgery. Results: All 8 active...

10.1080/08941939.2017.1408718 article EN Journal of Investigative Surgery 2018-01-09

Pregnancy-related aortic dissection (AoD) in Marfan syndrome is a lethal catastrophe. Due to its rarity and limited clinical experience, there no consensus regarding the optimal management strategy. We seek present our 21-year experience such patients , focusing on strategies early late outcomes.Between 1998 2019, we managed 30 pregnant women with (mean age 30.7 ± 4.3 years) who sustained AoD at mean of 28.3 8.8 weeks gestation (GWs). was acute 21 (70%), type A (TAAD) 24 (80%) B (TBAD) 6...

10.1093/ejcts/ezaa048 article EN European Journal of Cardio-Thoracic Surgery 2020-01-31

BACKGROUND Clostridium difficile (C. ) infection (CDI) is a rare clinical disease caused by changes in the intestinal microenvironment, which has variety of causes and poor prognosis, for there no standardized treatment. CASE SUMMARY A patient experienced recurrent difficulty bowel movements over past decade. Recently, symptoms worsened within last ten days, leading to clinic visit due constipation. The was subsequently referred our department. Preoperatively, diagnosed with obstructed colon...

10.4240/wjgs.v16.i9.3048 article EN World Journal of Gastrointestinal Surgery 2024-09-18

Background: Acute aorta dissection (AD) is a fatal emergency, however, studies addressing the clinical characteristics, management, and outcome of acute AD in young adult patients aged under 45 years China are very few.Methods: A retrospective study including 490 with as final diagnosis was conducted. Patients' demographics, medical history, laboratory diagnostic imaging findings were retrieved from records. Results: The median age 38 old an interquartile range 33 to 41. Male smoker...

10.1080/08941939.2018.1489916 article EN Journal of Investigative Surgery 2019-03-25

Massive bleeding throughout aortic repair in acute type A dissection (ATAAD) patients is a common but severe condition that can cause multiple serious clinical problems. Here, we report our findings regarding risk factors, short-term outcomes, and predicting model for massive ATAAD who underwent emergent repair.A universal definition of perioperative (UDPB) class 3 4 were used to define comprehensively evaluate patients. total 402 consecutive enrolled this retrospective study during 2019....

10.3389/fcvm.2022.892696 article EN cc-by Frontiers in Cardiovascular Medicine 2022-07-08

Several methods of arch vessel reconstruction, such as en bloc (island) and branched graft techniques, have been proposed to treat aortic pathologies during total replacement (TAR). We seek review our experience with modified technique left subclavian (LSCA)-left carotid artery (LCCA) transposition in TAR frozen elephant trunk (FET) procedure for chronic type A dissection (CTAAD).From September 2010 2016, 35 consecutive patients CTAAD underwent reconstruction LSCA-LCCA FET procedure....

10.21037/jtd.2018.08.140 article EN cc-by-nc-nd Journal of Thoracic Disease 2018-09-01

Background Aortic regurgitation (AR) related to Behcet's disease (BD) is rare, but usually fatal. Perivalvular leakage (PVL) high if AR BD treated with regular AVR. In this study, we report the surgical management of secondary BD. Methods Between September 2017 and April 2022, 38 patients had surgery in our center. 17 did not have a diagnosis before surgery, 2 them were diagnosed during received Bentall procedure. The remaining 15 conventional 21 as all modified procedures. All followed up...

10.3389/fcvm.2023.1093024 article EN cc-by Frontiers in Cardiovascular Medicine 2023-03-17

<b>Background</b> EuroSCORE is a widely used objective risk scoring model. <b>Objective</b> The aim of this study was to evaluate the validation II for predicting in-hospital mortality and length intensive care unit (ICU) stay after total aortic arch replacement with stented elephant trunk implantation DeBakey Type I dissection. <b>Patients Methods</b> Between February 2009 2012, data from 384 consecutive patients, who underwent surgery using implantation, were collected retrospectively....

10.1055/s-0033-1348197 article EN The Thoracic and Cardiovascular Surgeon 2013-06-17

To the Editor: For patients with acute DeBakey type I aortic dissection, ascending or hemiarch replacement can reduce surgical time and save lives in critical situations. However, residual distal dissection increases risk of dilatation, rupture, death.[1] In contrast, total arch (TAR) frozen elephant trunk (FET) implantation minimize need for re-intervention,[2] but may increase operative mortality, stroke, paraplegia, other complications. Currently, question optimal strategy remains...

10.1097/cm9.0000000000001416 article EN cc-by-nc-nd Chinese Medical Journal 2021-04-06

To investigate the effect of Codonopsis pilosula polysaccharide (CPP) on precancerous lesions gastric cancer (PLGC) and its mechanism. The CPP with more than 90% sugar content was prepared by water extraction alcohol precipitation combined column chromatography. MTT assay used to analyze survival rate human normal epithelial cells (GES-1) proliferation adenocarcinoma (AGS). PLGC animal model induced chemical irregular diet. alleviate related mechanism at high low doses (110 mg/kg 440 mg/kg)...

10.1016/j.prmcm.2024.100391 article EN cc-by-nc-nd Pharmacological Research - Modern Chinese Medicine 2024-02-07

Aortic dissection (AD), caused by tearing of the intima and avulsion aortic media, is a severe threat to patient life organ function. Iron closely related formation injury, but mechanism iron ion transport disorder in endothelial cells (ECs) remains unclear. We identified characteristic EC with overload single-cell RNA sequencing data. After intersecting homeostasis differentially expressed genes, it was found that hypoxia-inducible factor-1α (HIF-1α) divalent metal transporter 1 (DMT1) are...

10.7150/ijbs.99511 article EN cc-by-nc International Journal of Biological Sciences 2024-01-01

Prosthetic valve detachment after aortic replacement and pseudoaneurysm formation are the most important postoperative complications in patients with Takayasu arteritis regurgitation. We reviewed our experience of surgical treatment regurgitation disease.Between November 1997 September 2011, 11 (4 women 7 men) underwent treatment. The age ranged from 26 to 56 years (mean, 40 ± 9 years). Primary isolated was performed 1 patient, David procedure Wheat Bentall 2 patients, Cabrol 6 (including...

10.1532/hsf98.20121059 article EN The Heart Surgery Forum 2013-02-25

Postoperative acute kidney injury (AKI) is a major complication associated with increased morbidity and mortality after surgery for type A aortic dissection (AAAD). To the best of our knowledge, risk prediction models AKI following AAAD have not been reported. The goal present study was to develop model predict severe surgery.A total 485 patients who underwent were enrolled randomly divided into training cohort (70%) validation (30%). Severe defined as stage III Kidney Disease: Improving...

10.11909/j.issn.1671-5411.2022.10.003 article EN PubMed 2022-10-28

The aim of this study was to investigate the early and long-term outcomes after total arch replacement (TAR) frozen elephant trunk (FET) implantation in adult patients ≤30 years with acute type A aortic dissection (ATAAD).All young (≤30 years) ATAAD who underwent TAR FET between 2009 2017 were enrolled. end points major organ morbidity mortality, aortic-related events reoperation.The mean age all 83 25.9 (standard deviation, 3.3) years. in-hospital mortality 9.64% (8/83), 9 (10.8%) required...

10.1093/ejcts/ezad330 article EN European Journal of Cardio-Thoracic Surgery 2023-09-27
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