A5073037017- Radiomics and Machine Learning in Medical Imaging
- Cancer Risks and Factors
- Advanced Radiotherapy Techniques
- Medical Imaging Techniques and Applications
- Cancer Genomics and Diagnostics
- Breastfeeding Practices and Influences
- Renal cell carcinoma treatment
- Glioma Diagnosis and Treatment
- Radiopharmaceutical Chemistry and Applications
- Gastric Cancer Management and Outcomes
- Brain Metastases and Treatment
- Nutrition, Genetics, and Disease
- Pancreatic and Hepatic Oncology Research
- Lung Cancer Diagnosis and Treatment
- Breast Cancer Treatment Studies
- Colorectal and Anal Carcinomas
- RNA Research and Splicing
- Breast Lesions and Carcinomas
- Brain Tumor Detection and Classification
- S100 Proteins and Annexins
- Epigenetics and DNA Methylation
- Ferroptosis and cancer prognosis
- Erythropoietin and Anemia Treatment
- Cancer-related Molecular Pathways
- Simulation-Based Education in Healthcare
The Ohio State University
2017-2025
UW Health University Hospital
2023-2025
University of Wisconsin–Madison
2024-2025
University of Pikeville
2018-2024
Pikeville Medical Center
2024
OhioHealth
2022-2023
Riverside Methodist Hospital
2022-2023
Northwestern University
2021
University of Miami
2021
The Ohio State University Wexner Medical Center
2015-2021
Epidemiological studies associate an increase in breast cancer risk, particularly triple-negative (TNBC), with lack of breastfeeding. This is more prevalent African American women, significantly lower rate breastfeeding compared to Caucasian women. Prolonged leads gradual involution (GI), whereas short-term or abrupt (AI) the breast. Our previous study utilizing a murine model demonstrated precancerous changes, specifically hyperplasia, non-obligate precursor mammary glands AI mice. Here we...
Standard treatment of patients with stage II/III esophageal or gastroesophageal junction (E/GEJ) cancer involves neoadjuvant chemoradiation (nCRT), resection, and immunotherapy. Our trial evaluated the addition perioperative avelumab to standard treatments.
160 Background: About one-third of colorectal cancer (CRC) patients (pts) develop metastases, most commonly in the liver (CRLM). Ablative treatment multiple lesions is difficult and often not done with conventional CT-based radiation therapy, but feasible MRI-guided adaptive radiation. This study reviews our experience treating pts high burden CRLM using stereotactic body therapy (MRgRT). Methods: identified 4 or more treated MRgRT between 7/2019 4/2024, all whom had progressive disease...
S100A7 (Psoriasin) is an inflammatory protein known to be upregulated in breast cancer. However, the role of cancer has been elusive, since both pro- and anti-proliferative roles have reported different types cells animal models. To date, mechanism by which differentially regulates cell proliferation still not clear. We used Gene Functional Enrichment Analysis search for determining factor differential regulation. confirmed elaborated its regulating using vitro culture. further verified...
Oligometastatic state is believed to potentially represent a transitional stage between early, locoregional disease and widely metastatic disease. Historically, approaches, particularly in advanced colorectal cancers, have demonstrated efficacy select patients with limited burden of Recent strides systemic therapies, including biomarker-based treatments immunotherapy, alongside innovations surgical techniques novel approaches such as stereotactic radiotherapy ablation, ushered new era...
Recent clinical research describes a subset of glioblastoma patients that exhibit REP prior to the start radiation therapy. Current literature has thus far described this population using clinicopathologic features. To our knowledge, study is first investigate potential conventional radiomics, sophisticated multi-resolution fractal texture features, and different molecular features (MGMT, IDH mutations) as diagnostic prognostic tool for prediction from non-REP cases computational statistical...
652 Background: Radiation may have a role in management of patients with early-stage pancreatic cancer. However, the regional nodal irradiation (RNI) is not well defined despite high frequency occult disease. The goal this trial was to evaluate safety and feasibility stereotactic body radiation therapy (SBRT) primary disease RNI, combined capecitabine as neoadjuvant approach for resectable Updated survival analysis will be presented here. Methods: This prospective, single institution, phase...
Reports of mammary Paget's disease (MPD) as a manifestation breast cancer recurrence are rare. MPD presents particular challenge when emerging more than two decades after treated with evidence-based therapy. There is broad spectrum non-malignant causes for dermatitis the nipple during initial presentation that may delay work-up. This case highlights work-up and management in context personal history cancer. unique clinical emphasizes importance vigilant surveillance timely intervention,...
Abstract A significant challenge in brain metastases (BM) management is distinguishing radiation-induced treatment effect (TE) from tumor recurrence (TR). TE mimics the appearance of TR on follow-up MRI, making radiographic diagnosis unreliable. The standardized Response Assessment Neuro-Oncology for (RANO-BM) suboptimal due to high inter-reader variability. We compared performance artificial intelligence (AI)-driven MRI features with that RANO-BM criteria differentiating TR. hypothesize...
Athletes and bodybuilders use anabolic-androgenic steroids (AAS) to increase muscle mass enhance performance. Its is widespread among competitive athletes in order athletic performances. However, the of AAS has been linked many deleterious adverse effects, including cardiomyopathy polycythemia. We present case a young man his late 20s who presented with uncontrolled hypertension elevated hemoglobin. He was found have reduced left ventricular ejection fraction 20-25%. Further workup showed...