A5077847168- Colorectal Cancer Treatments and Studies
- Pancreatic and Hepatic Oncology Research
- Cancer Genomics and Diagnostics
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- Diversity and Career in Medicine
- Ethics in Clinical Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Esophageal Cancer Research and Treatment
- Health Systems, Economic Evaluations, Quality of Life
- Economic and Financial Impacts of Cancer
- Cardiovascular Function and Risk Factors
- Interprofessional Education and Collaboration
- Renal cell carcinoma treatment
- Cardiac Imaging and Diagnostics
- MRI in cancer diagnosis
- Cancer Immunotherapy and Biomarkers
- Esophageal and GI Pathology
- Gastrointestinal disorders and treatments
- Gallbladder and Bile Duct Disorders
- Pharmaceutical studies and practices
- Colorectal and Anal Carcinomas
- Patient-Provider Communication in Healthcare
- Pharmaceutical Practices and Patient Outcomes
- Healthcare Systems and Technology
University of Wisconsin–Madison
2022-2025
University of Wisconsin Carbone Cancer Center
2021-2025
University of Rochester Medical Center
2021-2024
London North West Healthcare NHS Trust
2024
Hillingdon Hospitals NHS Foundation Trust
2024
University of Michigan–Ann Arbor
2020-2022
Volpe National Transportation Systems Center
2021
Drexel University
2021
Strong Memorial Hospital
2021
Boston University
2020
Standard treatment of patients with stage II/III esophageal or gastroesophageal junction (E/GEJ) cancer involves neoadjuvant chemoradiation (nCRT), resection, and immunotherapy. Our trial evaluated the addition perioperative avelumab to standard treatments.
Introduction: High-quality communication and shared decision making (SDM) are crucial elements of effective patient care. SDM conversations intimate logistically challenging to capture. Evaluating alternative methods effectively observe how physicians conduct these may improve research efforts in this core discipline medicine.
160 Background: About one-third of colorectal cancer (CRC) patients (pts) develop metastases, most commonly in the liver (CRLM). Ablative treatment multiple lesions is difficult and often not done with conventional CT-based radiation therapy, but feasible MRI-guided adaptive radiation. This study reviews our experience treating pts high burden CRLM using stereotactic body therapy (MRgRT). Methods: identified 4 or more treated MRgRT between 7/2019 4/2024, all whom had progressive disease...
4034 Background: Neoadjuvant CRT followed by surgery is the standard of care for patients (pts) with stage II/III E/GEJ cancer, yet recurrence rates remain high. Immunotherapy has demonstrated activity in advanced cancer and was recently approved adjuvant treatment early disease. This trial evaluated safety efficacy avelumab perioperative resectable cancer. Methods: a two part phase I/II trial. Phase I run-in 6 pts. II planned to enroll an additional 18 pts expansion cohort. Pts...
Atrial fibrillation (AF) during high-dose melphalan and autologous stem-cell transplantation (HDM/SCT) for light-chain (AL) amyloidosis confers significant morbidity. Traditional risk factors provide limited prediction development of paroxysmal AF this vulnerable period. We sought to assess the association clinical echocardiographic parameters, including left atrial (LA) mechanics in patients undergoing HDM/SCT therapy. Baseline echocardiograms, electrocardiograms, electronic medical records...
548 Background: Cholangiocarcinoma (CCA) requires integrated efforts to understand the heterogeneity in available molecular targets. Chemotherapy remains a non-selective standard of care, however defining distinct populations with actionability critical need. The Veteran Health Administration’s (VHA) National Precision Oncology Program (NPOP) was established characterize comprehensive genomic profiles across VHA network. Methods: Veterans CCA underwent next-generation sequencing (NGS)...
11083 Background: Nationally, participation in oncology clinical trials is low, with lack of representation women and ethnic racial minorities. Interventions to increase patient enrollment ensure equity are necessary improve cancer care for all patients. Shared decision-making conversations physicians’ control amenable intervention. However, we must understand the current communication strategies used by medical oncologists their discussions patients about high-stakes treatment decisions,...
Changing behaviour as a result of learning from clinical practice is an important part improving the quality healthcare. The aims this study were to investigate educational influences that produce change in specialist trainees' and identify any differences types recalled between trainees primary secondary care.All 105 general (GPSTs) 100 first-year (STs) one deanery given opportunity take study. There three data collection phases: focus groups followed by questionnaire 13 semi-structured...
Abstract Background Although barriers to trial accrual are well‐reported, few studies have explored eligibility and offers as potential drivers of disparities in cancer clinical enrollment. Methods We identified patients with gastrointestinal (GI) or head/neck (HN) malignancies who were seen new at the University Michigan Health Rogel Cancer Center 2016. By exhaustive review electronic medical record, we assessed primary outcomes: (1) for, (2) documented offer of, (3) enrollment a trial. All...
Prime childbearing years occur during medical training and early career, leaving physicians with tough choices between family planning career growth. Restrictive workplace parental leave (PL) policies may negatively affect physician well-being. We evaluate existing PL lactation policies, as well return-to-work experiences, among oncology trainees early-career faculty.An anonymous 43-question cross-sectional survey was distributed via e-mail social media channels May June 2021 to within 5 of...
Introduction We report the case of a patient who experienced severe neurological symptoms collectively characterized as being “frozen” following second oxaliplatin infusion. Case A 52-year-old woman with metastatic colon cancer developed motor slowing, delayed and incomplete grip dorsiflexion, speech difficulty, visual impairment, leg cramping tingling after her infusion oxaliplatin. She was transferred from center to emergency room admitted hospital for further evaluation. Motor, verbal,...
11054 Background: Training and early career years coincide with childbearing raising young families, which places increased demands on new parents. With increasing numbers of female oncologists in the workforce, there is a need to assess amend current workplace lactation policies. We surveyed Medical Radiation Oncology trainees faculty policies practices regarding during training career. Methods: An anonymous 48 question cross-sectional survey developed by researchers expertise gender equity...
546 Background: Cholangiocarcinoma (CCA) has poor prognosis and limited treatment options. The US Veteran Health Administration’s (VHA) National Precision Oncology Program (NPOP) was established to characterize pathogenic drivers across the integrated VA network. Here, we summarize an important subgroup of CCA with homologous recombination deficiency (HRD) its impact on overall survival (OS). Methods: Next-generation sequencing (NGS) performed using FoundationOne CDx Analysis included...
Abstract Objectives The discharge medicines service (DMS) was introduced as an essential for all community pharmacies in England through the Community Pharmacy Contractual Framework (CPCF) February 2021. This study aimed to describe implementation of this paediatric patients and identify any barriers referrals. Methods undertaken a 24-bed ward District General Hospital from September 2022 2023. All inpatients on long-term medications were eligible inclusion. Out 169 participants, 149...
<h3>Aim</h3> Medicines-related patient safety incidents are more likely to occur when medicines reconciliation happens over 24 hours of admission an acute setting.<sup>1</sup> At our trust, the pharmacy team provide a weekend service, but this excludes paediatric patients. The aim audit was determine number patients admitted outside working (from Friday evening Sunday evening) 17 week period identify need include in service. <h3>Method</h3> Data collected from bed in-patient ward. normal...