Angela-Ștefania Marghescu

ORCID: 0000-0001-6536-206X
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About
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Research Areas
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
  • Lung Cancer Diagnosis and Treatment
  • Sarcoidosis and Beryllium Toxicity Research
  • Lung Cancer Treatments and Mutations
  • Occupational and environmental lung diseases
  • Antifungal resistance and susceptibility
  • Pleural and Pulmonary Diseases
  • Metastasis and carcinoma case studies
  • Hematological disorders and diagnostics
  • Bacillus and Francisella bacterial research
  • Medical Imaging and Pathology Studies
  • Long-Term Effects of COVID-19
  • Sarcoma Diagnosis and Treatment
  • Colorectal and Anal Carcinomas
  • COVID-19 and healthcare impacts
  • Eosinophilic Disorders and Syndromes
  • Global Cancer Incidence and Screening
  • Soft tissue tumor case studies

Institutul de Pneumoftiziologie "Marius Nasta"
2022-2024

Carol Davila University of Medicine and Pharmacy
2022-2024

Background and Objectives: The mainstay treatment of non-small-cell lung carcinoma is still surgery, but its impact on survival beyond nine years has never been reported/analysed in Romania. Therefore, we studied the clinical characteristics short- long-term a population 1369 patients diagnosed treated single institution, with variables included database being collected retrospectively. Materials Methods: In this paper, aimed to study number factors that might influence prognosis non-small...

10.3390/medicina60030415 article EN cc-by Medicina 2024-02-28

Pulmonary oncological pathologies are an important public health problem and the association with other pulmonary lesions may pose difficulties in diagnosis staging or require different treatment options. To address this complexity, we conducted a retrospective observational study at Marius Nasta Institute of Pneumophthisiology, Bucharest, Romania. Our focused on patients admitted 2019 non-small-cell lung carcinoma associated identified through surgical resection specimens. Among 314...

10.3390/cancers16101903 article EN Cancers 2024-05-16

A 66-year-old man, a 40-year smoker, was diagnosed with rheumatoid arthritis in 2018. He treated for one year methotrexate, and, later 2020, he interstitial pulmonary fibrosis. In 2022, treatment nintedanib initiated, clinical improvement being indicated but without showing functional or imaging benefit. The evolution of the disease rapidly progressive and unfavorable, death occurring due to thromboembolism. Following autopsy, triple lesions RA at lung level were confirmed: interstitial,...

10.3390/diagnostics14192175 article EN cc-by Diagnostics 2024-09-29

This review brings together the current knowledge regarding risk factors, and clinical, radiologic histological features of both post-COVID-19 interstitial pul-monary fibrosis (PCPF) Idiopathic Pulmonary Fibrosis (IPF) with a particular fo-cus on describing similarities disparities between fibrotic changes in these two diseases. It is important to highlight common points PCPF IPF observe if they are some targetable improve patient outcomes. The litera-ture was performed using numerous...

10.20944/preprints202305.0181.v1 preprint EN 2023-05-04

A rise in fungal infections has been observed worldwide among patients with extended hospital stays because of the severe infection caused by new coronavirus pandemic. 62-year-old female patient was admitted a form Coronavirus disease 2019 (COVID-19) and spent four weeks intensive care unit (ICU) requiring mechanical ventilation support before being moved to tertiary for further testing. Aspergillus fumigatus filamentous fungus, Candida spp., positive bacteriology multidrug-resistant...

10.3390/reports7020025 article EN cc-by Reports — Medical Cases Images and Videos 2024-04-05

Abstract The SARS-COV-2 pandemic had an important impact on the diagnosis of all pathologies, including lung cancer. According to Global Cancer Observatory 2020, cancer is leading cause death (18%). study aims are comparative evaluation and optimal identification factors that influenced establishment this in pre-pandemic periods. This retrospective included patients >18 years-old, diagnosed with carcinoma surgical specimens „Marius Nasta” Institute Pneumophtisiology, grouped two cohorts:...

10.2478/inmed-2024-0274 article EN Internal Medicine 2024-03-01

We present the clinical case of a 58-year-old female patient, smoker with occupational exposure to respiratory toxins, who was admitted our clinic following evaluation in an emergency department, where she diagnosed moderate right pleural effusion. Upon admission, patient exhibited symptoms, including progressive dyspnea exertion threshold, posterior pleuritic chest pain radiating anteriorly, occasional episodes low-grade fever, and persistent febrile symptoms lasting approximately two...

10.7759/cureus.74998 article EN Cureus 2024-12-02

Squamous cell carcinoma (SQCC) represents a significant proportion of human malignancies affecting various anatomical sites, including the lung. Understanding prognostic factors is crucial for establishing effective risk stratification in these patients, as multiple critical aspects significantly impact overall survival.

10.3390/diagnostics14202264 article EN cc-by Diagnostics 2024-10-11

We present the case of a 35-year-old patient without pathological history who developed hemopneumothorax due to altitude barotrauma during commercial airline flight. The computed tomography (CT) chest identified presence right hydropneumothorax and emphysema "blebs" bubbles. After therapeutic insertion drain tube, returned country by land transport. Three weeks later, he was diagnosed with right-sided pleurisy based on CT scan contrast material. A surgical intervention then performed, three...

10.3390/diagnostics13142367 article EN cc-by Diagnostics 2023-07-14

Multiple organs are affected by the systemic, granulomatous disease known as sarcoidosis, which has an unpredictable clinical course and unclear etiology. Systemic therapy is required for approximately 50% of patients with sarcoidosis to treat their illness. The usual first-line treatment oral glucocorticoids. Long-term high-dose use may cause significant morbidity in over time. We searched PubMed database articles about randomized controlled trials involving novel treatments conducted ten...

10.54044/rami.2023.04.05 article EN Romanian Archives of Microbiology and Immunology 2023-12-30

"A 64-year-old never-smoker man, with professional exposure, presented to Marius Nasta Pneumophtisiology Institute for fatigability effort, in the context of severe SARS-COV2 infection one month previously. His medical history includes pulmonary tuberculosis (55 years ago) and newly diagnosed type II diabetes (261 mg/dL glycemia). Clinical examination revealed no modification, except kyphoscoliosis, pale teguments mucosa, diminished vesicular breath sounds on right side. Blood pressure was...

10.54044/rami.2022.01.09 article EN Romanian Archives of Microbiology and Immunology 2022-03-31
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