A5045868483- Tuberculosis Research and Epidemiology
- Diagnosis and treatment of tuberculosis
- Infectious Diseases and Tuberculosis
- COVID-19 Clinical Research Studies
- Pneumocystis jirovecii pneumonia detection and treatment
- Lung Cancer Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Mycobacterium research and diagnosis
- Pneumonia and Respiratory Infections
- Respiratory Support and Mechanisms
- Lung Cancer Treatments and Mutations
- Diet, Metabolism, and Disease
- Neonatal Respiratory Health Research
- Pleural and Pulmonary Diseases
- COVID-19 diagnosis using AI
- Sarcoidosis and Beryllium Toxicity Research
- Tracheal and airway disorders
- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Radiomics and Machine Learning in Medical Imaging
- Intensive Care Unit Cognitive Disorders
- Cystic Fibrosis Research Advances
- Pediatric health and respiratory diseases
Carol Davila University of Medicine and Pharmacy
2014-2025
Institutul de Pneumoftiziologie "Marius Nasta"
2011-2025
UNNATI
2021
Titu Maiorescu University
2019
University College London
2019
Sheltering Arms Physical Rehabilitation Centers
1989
In this observational cohort study, sleep quality in post-COVID-19 patients was assessed using the Pittsburgh Sleep Quality Index (PSQI) questionnaire. This study aimed to examine aspects of who have undergone SARS-CoV-2 infection and if there is a pattern progression or regression over time (6 months). We also observed analyzed results order identify any possible links between severity COVID-19 as measured by PSQI The group consisted 65 adult with confirmed were referred pulmonologist for...
Despite advances in diagnostic technologies for tuberculosis (TB), global control of this disease requires improved active case finding selected vulnerable populations. The integration artificial intelligence (AI) into imaging modalities has been anticipated to assume a pivotal position conjunction with traditional bacteriological approaches, especially the diagnosis groups. study was conducted as prospective investigation spanning from November 2019 October 2023, Romania's national TB...
Background and Objectives: We conducted a retrospective observational study to evaluate the impact of elevated blood glucose levels in patients with SARS-CoV-2 infection prior diagnosis diabetes mellitus (DM) or newly diagnosed hyperglycemia. Materials Methods: This analyzed 6065 admitted COVID-19 departments "Marius Nasta" National Institute Pulmonology Bucharest, Romania, between 26 October 2020 5 January 2023. Of these, 813 (13.40%) were selected for analysis due either pre-existing DM...
We evaluated in this cohort study the predictive ability of 23 peripheral blood parameters and ratios for treatment outcomes after 2-month intensive phase patients with PTB. In 63 out 90 that turned culture negative, a significant decrease white cell count, neutrophils, monocyte, hemoglobin, platelet, plateletcrit, erythrocyte sedimentation rate, MLR, NLR, PLR SII values anti-TB therapy compared to pretreatment was observed (p <0.001). Logistic regression analysis generated model...
Romania has the highest tuberculosis (TB) burden in European Union/European Economic Area (EU/EEA) comprising almost a quarter (23.4%) of reported patients 2017, and TB notification rate six times higher than EU/EEA average. Although overall declined from 154/100.000 individuals to 66/100.000 general population between 2002 rates remain high certain vulnerable populations groups such as prisoners, homeless among drug users.We conducted descriptive study regarding monitoring data Romania,...
Our study objective was to construct models using 20 routine laboratory parameters on admission predict disease severity and mortality risk in a group of 254 hospitalized COVID-19 patients. Considering the influence confounding factors this single-center study, we also retrospectively assessed correlations between death within individual comorbidity subgroups. In multivariate regression by ROC curve analysis, model three (AUC 0.85; 95% CI: 0.79-0.91) six 0.86; 0.81-0.91) were able COVID-19,...
Abstract The study proposes a dynamic spatio‐temporal profile of the distribution tuberculosis incidence and air pollution in Romania, where this infectious disease induces more than 8,000 new cases annually. descriptive analysis for years 2012–2021 assumes an identification structuring patterns mycobacterium risk Romanian population, according to gender age, exploiting spatial modeling techniques time series data. Through autocorrelation, degree similarity between analyzed territorial...
Metabolic dysfunction-associated fatty liver disease (MAFLD) is a new term that no longer excludes patients consume alcohol or present other diseases, unlike nonalcoholic (NAFLD). The aim of this study was to evaluate the role different biomarkers as predictors MAFLD in with type 2 diabetes mellitus (T2DM). In regard, cross-sectional, non-interventional conducted over period 8 months T2DM. Liver steatosis displayed by abdominal ultrasound certified diagnosis. A percentage 49.5% studied...
Background and Objectives: The mainstay treatment of non-small-cell lung carcinoma is still surgery, but its impact on survival beyond nine years has never been reported/analysed in Romania. Therefore, we studied the clinical characteristics short- long-term a population 1369 patients diagnosed treated single institution, with variables included database being collected retrospectively. Materials Methods: In this paper, aimed to study number factors that might influence prognosis non-small...
Objective To implement and assess the mobile X-ray unit (MXU) equipped with digital radiography, computer-aided detection (CAD) software molecular point of care tests to improve early tuberculosis (TB) diagnosis in vulnerable populations a TB outreach screening programme Romania. Design Descriptive study. Settings Prisons Bucharest other cities southern part Romania, homeless shelters services for problem drug users Bucharest, Roma Craiova. Participants 5510 individuals attended MXU service;...
Air pollution is a serious problem in Romania, with the country ranking 13th among most polluted countries Europe 2021 World Quality Report. Despite recognized impact of pollutants on health, there has been lack large-scale studies conducted Romania. This study investigated air patients chronic respiratory, cardiovascular, cerebrovascular, or metabolic diseases Bucharest and its metropolitan area from 20 August 2018 to 1 June 2022. The daily limit values for particulate matter PM10 PM2.5...
Background European-specific policies for tuberculosis (TB) elimination require identification of key populations that benefit from TB screening. Aim We aimed to identify groups foreign-born individuals residing in European countries most targeted prevention Methods The Tuberculosis Network Trials group collected, by cross-sectional survey, numbers patients Union (EU) countries, Iceland, Norway, Switzerland and the United Kingdom (UK) 2020 10 highest ranked origin terms cases each country...
Mental health comorbidities are common among tuberculosis patients, with higher prevalence people rifampicin-resistant/multidrug-resistant (RR/MDR) tuberculosis. TB and depression share risk factors adding to the overall disease burden. There is limited evidence about of anxiety symptoms patients in Romania. We assessed their evolution over course treatment RR/MDR-TB receiving in-patient care at National Institute Pneumonology (NIP) “Marius Nasta” Romania during May-September 2020. conducted...
Introduction: Tuberculosis (TB) remains a global health challenge, requiring enhanced active case finding (ACF) through screening strategies. This study assesses the effectiveness of such an approach in locating TB cases among vulnerable groups, as homeless persons, injecting drug users, those detained prison, and people living rural areas. Methods: The focuses on socio-economic characteristics detection rates across Romanian counties using modern techniques including computer-aided lesions...
A 66-year-old man, a 40-year smoker, was diagnosed with rheumatoid arthritis in 2018. He treated for one year methotrexate, and, later 2020, he interstitial pulmonary fibrosis. In 2022, treatment nintedanib initiated, clinical improvement being indicated but without showing functional or imaging benefit. The evolution of the disease rapidly progressive and unfavorable, death occurring due to thromboembolism. Following autopsy, triple lesions RA at lung level were confirmed: interstitial,...
Abstract Tuberculosis (TB) is still a leading cause of morbidity and mortality worldwide. The impact on patient’s life significant, to physical, mental social deconditioning, not only in active TB but also post sequela. Although with specific antituberculous treatment sputum negativity can be achieved, extrapulmonary symptoms such as cachexia, muscle weakness depression may persist for long time. pulmonary rehabilitation (PR) useful tool this therapy sequela phase. benefits PR are: reducing...
During the SARS-CoV-2 pandemic period, in treatment approved by WHO, along with antivirals, antibiotics, nonsteroidal anti-inflammatory drugs and anticoagulants, dexamethasone was always used. This study started from professional concern related to vasopressor effect of cortisone on blood pressure (BP). The group achieved selecting, a total 356 patients hospitalized clinic, known hypertensive status at admission for SARS-CoV-2. Dexamethasone part anti-COVID-19 treatment, an administration...
We present the case of a 35-year-old patient without pathological history who developed hemopneumothorax due to altitude barotrauma during commercial airline flight. The computed tomography chest identified presence emphysema "blebs" and bubbles, histopathological examination lung fragment obtained diagnostic therapeutic thoracoscopy elements suggestive for diagnosis respiratory bronchiolitis associated with desquamative interstitial pneumonia (DIP).
Evaluation of the inflammatory response based on Interleukin 4 and 6 levels in patients with acquired bronchiectasis (non-cystic fibrosis) healthy controls. The study was conducted a group 77 subjects, divided into 2 lots: first lot consisting 57 objectified by Computed Tomography 20 individuals. serum Interleukins were measured using ELISA biochemical spectrophotometry test. results are significant from statistical point view, especially when it comes to mean value that much higher control...
Obesity and Overweight have the highest rate of incidence prevalence in past 3 decades, as global pathologies. The purpose this study was to evaluate cardiovascular, classic modern risk factors overweight obese patients by studying lipid metabolism (total cholesterol, HDL-cholesterol, non-HDL-cholesterol, LDL-cholesterol, serum triglycerides), glucose metabolism, insulin resistance sensitivity, hypertension (HBP) metabolic syndrome (MS). This analytical performed on 111 subjects divided...