Helena Liira

ORCID: 0000-0001-6577-3109
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About
Contact & Profiles
Research Areas
  • Research in Social Sciences
  • Primary Care and Health Outcomes
  • Sinusitis and nasal conditions
  • Pharmaceutical Practices and Patient Outcomes
  • Maternal Mental Health During Pregnancy and Postpartum
  • Musculoskeletal pain and rehabilitation
  • Healthcare Systems and Technology
  • Interprofessional Education and Collaboration
  • Antibiotic Use and Resistance
  • Pneumonia and Respiratory Infections
  • Long-Term Effects of COVID-19
  • Cardiac Health and Mental Health
  • Physical Activity and Health
  • Health Sciences Research and Education
  • Health Systems, Economic Evaluations, Quality of Life
  • Workplace Health and Well-being
  • Psychosomatic Disorders and Their Treatments
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Innovations in Medical Education
  • Medication Adherence and Compliance
  • Drug-Induced Adverse Reactions
  • Pregnancy and Medication Impact
  • Pain Mechanisms and Treatments
  • Health and Wellbeing Research
  • Infection Control in Healthcare

University of Helsinki
2014-2025

Helsinki University Hospital
2015-2025

The University of Western Australia
2015-2023

Primary Health Care
2010-2020

Tampere University
2013

Children's Hospital of Eastern Ontario
2013

Izaak Walton Killam Health Centre
2010

General practitioners (GPs) manage the drug therapies of people with chronic diseases, and poor adherence to medication remains a major challenge.This qualitative study examined GPs' insights into non-adherence ways overcoming this problem.We ran four focus groups comprising 16 GPs at Kirkkonummi Health Centre (Southern Finland). Interviews were audiotaped, transcribed verbatim analysed by inductive content analysis.The two main themes in discussions care disease increased need for medicine...

10.1136/bmjopen-2016-015332 article EN cc-by-nc BMJ Open 2018-01-01

The 'Oslo Chronic Fatigue Consortium' consists of researchers and clinicians who question the current narrative that chronic fatigue syndromes, including post-covid conditions, are incurable diseases. Instead, we propose an alternative view, based on research, which offers more hope to patients. Whilst regard symptoms these conditions as real, they likely reflect brain's response a range biological, psychological, social factors, rather than specific disease process. Possible causes include...

10.1080/02813432.2023.2235609 article EN cc-by Scandinavian Journal of Primary Health Care 2023-09-23

Background Persistent somatic symptoms unexplained by a defined medical or psychiatric condition often include component of central sensitization. Many treatment options are based on cognitive behavioral therapy. Effective widely available therapies scarce. There self-management programs and e-therapies that aim at overcoming the sensitization modifying interoceptive neural networks in brain. Objectives This study aims to investigate effect mindfulness-based amygdala insula retraining (AIR)...

10.1371/journal.pone.0316169 article EN cc-by PLoS ONE 2025-02-12

Background The mechanisms underlying persistent symptoms after non-severe COVID-19 remain unclear. This study aimed to investigate transcriptomic changes in peripheral blood cells of patients with post-COVID-19 condition (PCC) and assess if distinct clinical subtypes specific gene signatures could be identified. Methods cohort included 111 PCC from the SARS-CoV-2 Omicron variant era, 57 recovered (Recov) 54 having prolonged indicative PCC. results were compared 63 healthy controls (Ctrl)...

10.3389/fimmu.2025.1500997 article EN cc-by Frontiers in Immunology 2025-03-21

Objective: To present the occurrence, characteristics, etiology, interference, and medication of chronic pain among elderly living independently at home. Design/setting: A total 460 subjects in three cohorts aged 75, 80 85 years respectively received visits by communal home-care department nurses for a cross-sectional survey. Of them, 175 had (duration ≥ 3 months) with an average intensity 4/10 and/or moderate interference daily life. Main outcome measures: Clinical assessment was performed...

10.3109/02813432.2016.1160628 article EN cc-by-nc Scandinavian Journal of Primary Health Care 2016-04-02

Objectives The aim of this study was to assess the effect an ergonomic intervention on pain and sickness absence caused by upper-extremity musculoskeletal disorders. Methods In randomized controlled study, subjects aged 18–60 years (N=177) seeking medical advice due symptoms were included if their symptoms, or exacerbation had started <30 days prior consultation imme­diate sick leave not required. Workplace improvements made in group. Data absences gathered during one-year follow-up. Results...

10.5271/sjweh.3141 article EN cc-by Scandinavian Journal of Work Environment & Health 2011-01-10

Although a number of studies have evaluated the effectiveness computerized decision-support systems (CDSS), there is lack data on user perspectives, barriers, and facilitators to implementation CDSSs in real-life surroundings. The aim this study was assess individually perceived ideas influencing CDSS usability. In qualitative study, five focus groups were carried out with physicians nurses separately at Tampere City Health Center, Finland. participants end-users EBMeDS decision support...

10.1186/s12911-016-0245-z article EN cc-by BMC Medical Informatics and Decision Making 2015-12-01

Hazardous and harmful alcohol use high blood pressure are central risk factors related to premature non-communicable disease (NCD) mortality worldwide. A reduction in the prevalence of both has been suggested as a route reach global NCD targets. This study aims highlight that screening interventions for hypertension hazardous primary healthcare can contribute substantially achieving targets.A consensus conference based on systematic reviews, meta-analyses, clinical guidelines, experimental...

10.1186/s12916-017-0934-1 article EN cc-by BMC Medicine 2017-09-21

Objective. To explore medical students’ potential interest in family medicine the future and their perceptions of a GP's work. Design. A cross-sectional survey 2008–2010. Setting subjects. Fifth-year students prior to main course General Practice at University Helsinki. Main outcome measures. The opinions regarding work aims Results. 309/359 (mean age 25.7 years, 64% females) responded survey. Among students, 76% considered most attractive feature be that it is versatile challenging. least...

10.3109/02813432.2012.654194 article EN cc-by Scandinavian Journal of Primary Health Care 2012-02-19

We aimed to identify clinically relevant clusters among patients with post-Covid-19 condition (PCC) and assess prognosis overall within clusters. Prospective cohort study of PCC attending a rehabilitation clinic. monitored patient reported outcome measures (PROMs): EuroHIS quality life symptoms. Unsupervised hierarchical cluster analyses were performed different quantity symptoms, symptoms presenting together. Preliminary findings on symptom prevalence at 12 months are reported. Among 409...

10.1016/j.jpsychores.2024.111808 article EN cc-by Journal of Psychosomatic Research 2024-05-21

Background. Evidence-based clinical guidelines could support shared decision-making and help patients to participate actively in their care. However, it is not well known how view as a source of health information. This qualitative study aimed assess what know about guidelines, they think presentation formats. Research question. What the role information for implementation evidence-based be improved? Methods. A with focus groups that were built around semi-structured topic guide. Focus...

10.3109/02813432.2015.1067517 article EN cc-by-nc Scandinavian Journal of Primary Health Care 2015-07-03

Aims: We examined the associations of physical activity (PA) frequency with self-rated health (SRH), well-being (SRW) and depressive symptoms, in middle-aged men Finland. Methods: The cross-sectional study comprised 665 (mean age 41 ± 3 SD years; body mass index (BMI) 26.8 4.2 kg/m 2 ), who had completed screening questionnaire an intervention for cardiovascular risk factors. Their weekly PA was assessed by a questionnaire, SRH SRW visual analog scales (VAS), symptoms Patient Health...

10.1177/1403494814561820 article EN Scandinavian Journal of Public Health 2014-12-12

Background Psychotropic medication use occurs in 8% of pregnancies, with rates increasing, and often multiple medications prescribed. Aims This study aims to determine if the psychotropic medication, a cohort women severe mental illness, increases special care nursery admission reports differences between antidepressant antipsychotic either alone or combination. Methods A retrospective database analysis from illness pregnancy identified 268 pregnant who were grouped according type....

10.1111/ajo.12621 article EN Australian and New Zealand Journal of Obstetrics and Gynaecology 2017-04-07

Introduction: Lithium treatment in pregnancy represents a significant dilemma for women and treating health professionals alike. The complexity of risk-benefit analysis is impacted by limited information.Methods: A cohort study 33 with severe mental illness, who were prescribed lithium at any time during the pregnancy, gave birth between December 2007 January 2015 specialist antenatal clinic Western Australia. descriptive comparison continued throughout those ceased on discovery was...

10.1080/0167482x.2017.1337743 article EN Journal of Psychosomatic Obstetrics & Gynecology 2017-06-15

Introduction After COVID-19, many continue to experience persistent debilitating symptoms, that is, long COVID. Its most prevalent symptoms are chest pain, difficulties with breathing, painful muscles, ageusia or anosmia, tingling extremities and general tiredness. This paper describes the protocol of Long COVID Cohort Study assess prognosis prognostic determinants patients by implementing patient-reported outcome measures (PROMs), (PREMs) clinical examinations during a 1-year follow-up....

10.1136/bmjopen-2023-072935 article EN cc-by-nc BMJ Open 2023-10-01

Objective: Research and PhDs are relatively rare in family medicine primary care. To promote research, regular one-year research courses for care professionals with a focus on clinical epidemiology were started. This study explores the academic outcomes of first four cohorts surveys participants’ perspectives course. Design: An electronic survey was sent to course participants. All peer-reviewed scientific papers published by these students retrieved literature searches PubMed. Setting:...

10.3109/02813432.2015.1132893 article EN cc-by-nc Scandinavian Journal of Primary Health Care 2016-01-02
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