- Substance Abuse Treatment and Outcomes
- Social Policy and Reform Studies
- European Law and Migration
- Opioid Use Disorder Treatment
- Alcohol Consumption and Health Effects
- HIV, Drug Use, Sexual Risk
- Health and Medical Studies
- Hepatitis C virus research
- Mental Health Treatment and Access
- Health Policy Implementation Science
- Social Policies and Healthcare Reform
- Psychiatric care and mental health services
- Homelessness and Social Issues
- COVID-19 and Mental Health
- Virus-based gene therapy research
- Social and Demographic Issues in Germany
- Medical and Health Sciences Research
- European Socioeconomic and Political Studies
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- Schizophrenia research and treatment
- Chronic Disease Management Strategies
- Health Promotion and Cardiovascular Prevention
- Global Public Health Policies and Epidemiology
- Discrimination and Equality Law
University Medical Center Hamburg-Eppendorf
2015-2025
Universität Hamburg
2016-2025
Praxis für Humangenetik Tübingen
2024
Klinik und Poliklinik für Psychiatrie und Psychotherapie
2020-2022
Newcastle University
2021
General University Hospital in Prague
2021
Sechenov University
2021
TU Dresden
2021
Charles University
2021
Centre for Addiction and Mental Health
2021
To investigate changes in alcohol consumption during the first months of COVID-19 pandemic Europe as well its associations with income and experiences distress related to pandemic.Cross-sectional on-line survey conducted between 24 April 22 July 2020.Twenty-one European countries.A total 31 964 adults reporting past-year drinking.Changes were measured by asking respondents about over previous month their drinking frequency, quantity they consumed incidence heavy episodic events. Individual...
Highlights•Chronic HCV prevalence and treatment rates among PWID vary widely across Europe.•HCV scale-up is required in most sites to reduce transmission.•Increasing OST/NSP coverage enhances prevention benefit.Graphical abstractAbstractBackground & AimsPrevention of hepatitis C virus (HCV) transmission people who inject drugs (PWID) critical for eliminating Europe. We estimated the impact current scaled-up with without scaling up opioid substitution therapy (OST) needle syringe programmes...
SARS-CoV-2 reached Europe in early 2020 and disrupted the private public life of its citizens, with potential implications for substance use. The objective this study was to describe possible changes use first months pandemic Europe.Data were obtained from a cross-sectional online survey 36,538 adult users 21 European countries conducted between April 24 July 22 2020. Self-perceived measured by asking respondents whether their had decreased (slightly or substantially), increased not changed...
Zusammenfassung. Zielsetzung: Ziel der vorliegenden Studie war, die Veränderung des Alkoholkonsums während SARS-CoV-2 Pandemie in Deutschland zu untersuchen und mit derer anderer europäischer Länder vergleichen. Methodik: Analyse von soziodemographischen sozioökonomischen Daten sowie Angaben zur seit einer europaweiten Onlinebefragung (n=40.064) aus 21 Ländern. Zur Anpassung an Bevölkerungsverteilung den Ländern erfolgte eine Gewichtung anhand Geschlecht, Alter Bildungsabschluss. Ergebnisse:...
A variety of treatment options for people with alcohol use disorder (AUD) exist. Surveys estimate that 1 in 10 AUD utilise treatment, but real-world pathways remain covert. This data-linkage study seeks to characterise utilisation patterns identify gaps access and delivery Germany. Linking individual-level data from three sources (statutory health insurance, pension funds, outpatient addiction care services) identified seven alcohol-related types delivered (brief psychiatric consultation;...
Introduction: For people with alcohol use disorder (AUD), the German treatment guidelines recommend inpatient qualified withdrawal (QWT; physical plus psychosocial to enhance motivation abstain from drinking) and post-acute rehabilitation treatment. This study is first (a) evaluate re-hospitalisation among AUD patients receiving different treatments (b) model avoided if more were receive treatment.Methods: Electronic health records (2016-2021) living in city-state of Hamburg (Germany)...
Gastrointestinal stromal tumors (GIST) are the most frequent mesenchymal of gastrointestinal tract. The biological appearance these reaches from small lesions with benign to aggressive sarcomas. Only 3–5% GISTs localized in duodenum. There is a controversy, if duodenal should be treated by duodenopancreatectomy or limited resection A 29-year-old man presented an acute upper bleeding submucosal tumor located proximal part III duodenum, 3 cm distal papilla Vater. After emergency laparotomy...
Opioid addiction is one of the most common substance-related disorders worldwide, and morbidity mortality due to opioid place a heavy burden on society. Knowing size population that addicted opioids prerequisite for development implementation appropriate health-policy measures.Our estimate Germany 2016 based an enumeration opioid-addicted persons who were entered in registry receiving substitution therapy, outpatient inpatient care without extrapolation all facilities, estimation number not...
Abstract Background According to the German guidelines, people with severe alcohol use disorders (AUDs) should receive withdrawal treatment. Compared somatic treatment (SWT), extended duration and psychosocial elements of so-called “qualified treatment” (QWT) aim reduce relapse rates. Despite promising results prospective studies on QWT, only few inpatients seeking QWT. We estimated potential effects mortality morbidity for higher proportions treatment-seeking patients receiving QWT rather...
Collaborative and stepped care (CSC) models are recommended in guidelines because of their documented effectiveness treating depression anxiety disorders. The evidence for efficacy against other mental disorders is limited. In this study, we evaluated the a collaborative model (COMET) patients with depressive, anxiety, somatoform and/or alcohol-related related comorbidities outpatient setting Germany. We conducted prospective, cluster-randomized, controlled, parallel-group superiority trial;...
Knowledge of health-related quality life (HRQOL) patients receiving opioid substitution treatment (OST) is limited and fragmented. The present study examines the HRQOL a large national sample OST in Germany sociodemographic clinical correlates. Cross-sectional data on 2176 was compared with German general population norms. Patients were recruited from 63 practices across Germany. To identify correlates HRQOL, as measured SF-12, we performed bi- multivariate analyses variables, including...
Hazardous and harmful alcohol use high blood pressure are central risk factors related to premature non-communicable disease (NCD) mortality worldwide. A reduction in the prevalence of both has been suggested as a route reach global NCD targets. This study aims highlight that screening interventions for hypertension hazardous primary healthcare can contribute substantially achieving targets.A consensus conference based on systematic reviews, meta-analyses, clinical guidelines, experimental...
Abstract Background The coronavirus disease 2019 pandemic has been linked to changes in alcohol consumption, access healthcare services and alcohol-attributable harm. In this contribution, we quantify alcohol-specific mortality hospitalizations at the onset of COVID-19 March 2020 Germany. Methods We obtained monthly counts deaths hospital discharges between January 2013 December (n = 96 months). Alcohol-specific (International Classification Diseases, tenth revision codes: F10.X; G31.2,...